SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ap1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		5 / 12 LEU A 249
LEU A 253
VAL A 154
ARG A 153
VAL A  73
 None
 1.41A 1hrkB-3ap1A:
undetectable		 1hrkB-3ap1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifA-3ap1A:
undetectable		 1kifA-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifB-3ap1A:
undetectable		 1kifB-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifC-3ap1A:
undetectable		 1kifC-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifD-3ap1A:
undetectable		 1kifD-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifE-3ap1A:
undetectable		 1kifE-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifF-3ap1A:
undetectable		 1kifF-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifG-3ap1A:
undetectable		 1kifG-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 TYR A 325
TYR A 334
ARG A 186
GLY A 185
 None
 1.09A 1kifH-3ap1A:
2.2		 1kifH-3ap1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		3 / 3 ARG A  95
GLY A 275
SER A 261
 None
 0.64A 2xctB-3ap1A:
undetectable		 2xctB-3ap1A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_B_DXCB92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 5 VAL A 154
VAL A  94
ARG A 153
LYS A 250
 None
 1.21A 3rv5A-3ap1A:
undetectable
3rv5B-3ap1A:
0.0		 3rv5A-3ap1A:
12.69
3rv5B-3ap1A:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		5 / 12 MET A 181
LEU A 179
LEU A 241
ALA A  86
LEU A  88
 None
 1.31A 4m11A-3ap1A:
undetectable		 4m11A-3ap1A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 7 LYS A 164
LEU A 163
GLY A  75
GLY A  74
 None
 0.81A 5a06A-3ap1A:
undetectable		 5a06A-3ap1A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 7 LYS A 164
LEU A 163
GLY A  75
GLY A  74
 None
 0.79A 5a06B-3ap1A:
undetectable		 5a06B-3ap1A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 7 LYS A 164
LEU A 163
GLY A  75
GLY A  74
 None
 0.79A 5a06C-3ap1A:
undetectable		 5a06C-3ap1A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 7 LYS A 164
LEU A 163
GLY A  75
GLY A  74
 None
 0.79A 5a06E-3ap1A:
undetectable		 5a06E-3ap1A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 7 LYS A 164
LEU A 163
GLY A  75
GLY A  74
 None
 0.80A 5a06F-3ap1A:
undetectable		 5a06F-3ap1A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3ap1 PROTEIN-TYROSINE
SULFOTRANSFERASE 2
(Homo
sapiens) 		4 / 7 THR A  82
ASP A 287
ILE A 290
VAL A 289
 A3P  A   1 (-3.6A)
None
None
A3P  A   1 (-3.8A)
 0.82A 5ik1A-3ap1A:
undetectable		 5ik1A-3ap1A:
20.84