SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3apq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		4 / 6 LEU A 192
ILE A 132
TRP A 168
TYR A 154
 None
 1.03A 1db1A-3apqA:
1.5		 1db1A-3apqA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		5 / 11 ASN A 152
VAL A 151
PHE A 150
ASN A 217
ALA A 213
 None
 1.13A 2iyfA-3apqA:
undetectable		 2iyfA-3apqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		5 / 12 ASN A 152
VAL A 151
PHE A 150
ASN A 217
ALA A 213
 None
 1.15A 2iyfB-3apqA:
2.9		 2iyfB-3apqA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_C_P77C203_1
(PROTEIN S100-A4)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		5 / 10 ASP A 176
PHE A 171
PHE A 228
ILE A 206
LEU A 148
 None
 1.46A 3m0wC-3apqA:
undetectable
3m0wD-3apqA:
undetectable
3m0wE-3apqA:
undetectable
3m0wF-3apqA:
undetectable		 3m0wC-3apqA:
19.76
3m0wD-3apqA:
19.76
3m0wE-3apqA:
19.76
3m0wF-3apqA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_H_P77H203_1
(PROTEIN S100-A4)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		5 / 10 LEU A 148
PHE A 228
ILE A 206
PHE A 171
ASP A 176
 None
 1.45A 3m0wE-3apqA:
undetectable
3m0wF-3apqA:
undetectable
3m0wG-3apqA:
undetectable
3m0wH-3apqA:
undetectable		 3m0wE-3apqA:
19.76
3m0wF-3apqA:
19.76
3m0wG-3apqA:
19.76
3m0wH-3apqA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_I_P77I203_1
(PROTEIN S100-A4)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		5 / 10 LEU A 148
PHE A 228
ILE A 206
ASP A 176
PHE A 171
 None
 1.48A 3m0wA-3apqA:
undetectable
3m0wB-3apqA:
undetectable
3m0wI-3apqA:
undetectable
3m0wJ-3apqA:
undetectable		 3m0wA-3apqA:
19.76
3m0wB-3apqA:
19.76
3m0wI-3apqA:
19.76
3m0wJ-3apqA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		5 / 11 ASN A 152
VAL A 151
PHE A 150
ASN A 217
ALA A 213
 None
 1.11A 4m83A-3apqA:
undetectable		 4m83A-3apqA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		4 / 6 TYR A 154
ASP A 126
TYR A 117
TYR A  84
 None
 1.35A 5igyA-3apqA:
undetectable		 5igyA-3apqA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 3apq DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		4 / 8 LEU A  39
LEU A  40
LEU A  78
GLY A 110
 None
 0.94A 6ce2A-3apqA:
1.3		 6ce2A-3apqA:
19.14