SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aps'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3aps DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		4 / 7 ASP A 694
PHE A 706
TYR A 743
PRO A 744
 None
None
GOL  A 790 (-4.4A)
None
 1.29A 2q6kA-3apsA:
undetectable		 2q6kA-3apsA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 3aps DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		5 / 9 ILE A 771
ILE A 775
LYS A 778
LEU A 748
GLU A 761
 None
 0.97A 3f78A-3apsA:
undetectable		 3f78A-3apsA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3aps DNAJ HOMOLOG
SUBFAMILY C MEMBER
10
(Mus
musculus) 		4 / 7 PHE A 706
VAL A 746
ILE A 771
SER A 672
 None
 0.95A 3pglA-3apsA:
undetectable		 3pglA-3apsA:
22.51