SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aq0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 4 THR A 209
LEU A 208
VAL A 154
LEU A 146
None
1.05A 1fbmB-3aq0A:
undetectable
1fbmB-3aq0A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
7 / 11 SER A 103
LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
FPP  A1002 (-4.2A)
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.66A 1rqjA-3aq0A:
29.3
1rqjA-3aq0A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
7 / 11 SER A 103
LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
FPP  A1002 (-4.2A)
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.65A 1rqjB-3aq0A:
29.1
1rqjB-3aq0A:
28.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 LEU A 158
ALA A 156
LEU A 146
LYS A 203
ALA A 204
None
1.36A 1sn0A-3aq0A:
undetectable
1sn0C-3aq0A:
undetectable
1sn0A-3aq0A:
15.52
1sn0C-3aq0A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 11 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.71A 1yhlA-3aq0A:
23.8
1yhlA-3aq0A:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 11 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.61A 1yq7A-3aq0A:
25.1
1yq7A-3aq0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.72A 1yv5A-3aq0A:
25.3
1yv5A-3aq0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.81A 1zw5A-3aq0A:
25.8
1zw5A-3aq0A:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 12 LEU A 197
ALA A 102
LEU A 139
LEU A 165
VAL A 166
None
FPP  A1002 (-4.1A)
None
FPP  A1002 ( 4.6A)
FPP  A1002 ( 4.1A)
1.02A 2c12C-3aq0A:
undetectable
2c12C-3aq0A:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.69A 2e91A-3aq0A:
22.5
2e91A-3aq0A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.69A 2e91B-3aq0A:
21.3
2e91B-3aq0A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.70A 2f89F-3aq0A:
26.4
2f89F-3aq0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 11 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.76A 2f8cF-3aq0A:
26.0
2f8cF-3aq0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.75A 2f8zF-3aq0A:
26.4
2f8zF-3aq0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 12 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.61A 2f94F-3aq0A:
25.8
2f94F-3aq0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.73A 2f9kF-3aq0A:
25.8
2f9kF-3aq0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 9 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.57A 2o1oA-3aq0A:
23.7
2o1oA-3aq0A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.81A 2o1oB-3aq0A:
25.6
2o1oB-3aq0A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.85A 2q58A-3aq0A:
24.0
2q58A-3aq0A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.91A 2q58B-3aq0A:
25.3
2q58B-3aq0A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.54A 2qisA-3aq0A:
25.8
2qisA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 6 LEU A 165
ALA A 102
LEU A 139
ALA A 142
FPP  A1002 ( 4.6A)
FPP  A1002 (-4.1A)
None
None
0.86A 2vcvB-3aq0A:
undetectable
2vcvB-3aq0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_B_ASDB1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 6 LEU A 197
ALA A 102
LEU A 139
ALA A 142
None
FPP  A1002 (-4.1A)
None
None
0.86A 2vcvB-3aq0A:
undetectable
2vcvB-3aq0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 6 LEU A 165
ALA A 102
LEU A 139
ALA A 142
FPP  A1002 ( 4.6A)
FPP  A1002 (-4.1A)
None
None
0.91A 2vcvK-3aq0A:
1.0
2vcvK-3aq0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_K_ASDK1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 6 LEU A 197
ALA A 102
LEU A 139
ALA A 142
None
FPP  A1002 (-4.1A)
None
None
0.87A 2vcvK-3aq0A:
1.0
2vcvK-3aq0A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.68A 3ez3A-3aq0A:
25.8
3ez3A-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.72A 3ez3B-3aq0A:
25.5
3ez3B-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.71A 3ez3C-3aq0A:
25.8
3ez3C-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.68A 3ez3D-3aq0A:
25.2
3ez3D-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 10 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.64A 3ibaA-3aq0A:
25.2
3ibaA-3aq0A:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.69A 3ldwA-3aq0A:
25.7
3ldwA-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.75A 3ldwB-3aq0A:
25.5
3ldwB-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.71A 3ldwC-3aq0A:
25.7
3ldwC-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.76A 3ldwD-3aq0A:
25.3
3ldwD-3aq0A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 11 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.74A 3n45F-3aq0A:
25.8
3n45F-3aq0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.74A 3n46F-3aq0A:
25.7
3n46F-3aq0A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 LEU A 246
PHE A 239
ILE A 254
GLY A 299
LYS A 298
None
1.48A 3oshA-3aq0A:
undetectable
3oshA-3aq0A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ALA A 219
GLY A 223
LEU A 336
LEU A 226
ASN A 225
None
1.42A 3wdmA-3aq0A:
undetectable
3wdmA-3aq0A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.50A 4kfaA-3aq0A:
25.5
4kfaA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.67A 4kpdA-3aq0A:
26.3
4kpdA-3aq0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 9 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.70A 4kpjA-3aq0A:
25.4
4kpjA-3aq0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.71A 4kq5A-3aq0A:
25.4
4kq5A-3aq0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.69A 4kqsA-3aq0A:
26.2
4kqsA-3aq0A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
ISY  A1003 (-4.7A)
0.75A 4n9uA-3aq0A:
25.8
4n9uA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
ISY  A1003 (-4.7A)
1.31A 4n9uA-3aq0A:
25.8
4n9uA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 12 LEU A 104
ASP A 107
ASP A 111
ARG A 116
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
ISY  A1003 (-4.7A)
0.61A 4ng6A-3aq0A:
26.0
4ng6A-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 12 LEU A 104
ASP A 107
ASP A 111
ARG A 116
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
ISY  A1003 (-4.7A)
1.29A 4ng6A-3aq0A:
26.0
4ng6A-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.68A 4nkeA-3aq0A:
25.5
4nkeA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.58A 4nkfA-3aq0A:
25.9
4nkfA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 LEU A 104
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.75A 4nkfA-3aq0A:
25.9
4nkfA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.69A 4nuaA-3aq0A:
25.8
4nuaA-3aq0A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 9 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.75A 4oguA-3aq0A:
25.6
4oguA-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
3 / 3 VAL A  29
ALA A  37
PHE A 137
None
0.86A 4olbA-3aq0A:
undetectable
4olbA-3aq0A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.81A 4p0vA-3aq0A:
26.4
4p0vA-3aq0A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 11 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.76A 4p0wA-3aq0A:
26.3
4p0wA-3aq0A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 10 LEU A 197
LEU A 165
ALA A 161
LEU A 139
LEU A 158
None
FPP  A1002 ( 4.6A)
None
None
None
1.27A 4p65A-3aq0A:
undetectable
4p65B-3aq0A:
undetectable
4p65F-3aq0A:
undetectable
4p65H-3aq0A:
undetectable
4p65A-3aq0A:
4.03
4p65B-3aq0A:
8.80
4p65F-3aq0A:
8.80
4p65H-3aq0A:
8.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.59A 4q23A-3aq0A:
25.3
4q23A-3aq0A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.67A 4rxdA-3aq0A:
24.5
4rxdA-3aq0A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.67A 4rxdB-3aq0A:
24.6
4rxdB-3aq0A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 10 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.66A 4rxdC-3aq0A:
24.7
4rxdC-3aq0A:
24.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 8 SER A 103
LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
FPP  A1002 (-4.2A)
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.65A 4umjA-3aq0A:
28.9
4umjA-3aq0A:
30.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
7 / 9 SER A 103
LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
FPP  A1002 (-4.2A)
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.61A 4umjB-3aq0A:
29.1
4umjB-3aq0A:
30.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
3 / 3 VAL A  29
ALA A  37
PHE A 137
None
0.86A 4w5nA-3aq0A:
undetectable
4w5nA-3aq0A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
3 / 3 VAL A  29
ALA A  37
PHE A 137
None
0.86A 4z4iA-3aq0A:
undetectable
4z4iA-3aq0A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 12 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.67A 5cg5A-3aq0A:
25.2
5cg5A-3aq0A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
6 / 12 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
THR A 194
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
ISY  A1003 (-4.7A)
0.65A 5cg6A-3aq0A:
25.7
5cg6A-3aq0A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
3 / 3 ASP A 234
LEU A 104
ARG A 116
None
None
FPP  A1002 (-2.9A)
0.54A 5e8qA-3aq0A:
undetectable
5e8qA-3aq0A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
5 / 9 LEU A 104
ASP A 107
ASP A 111
ARG A 116
LYS A 193
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.74A 5eroA-3aq0A:
25.6
5eroA-3aq0A:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
3 / 3 VAL A  29
ALA A  37
PHE A 137
None
0.83A 5js1A-3aq0A:
undetectable
5js1A-3aq0A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 4 LEU A 339
ASP A   9
PRO A  10
ARG A 342
None
1.26A 6fgdA-3aq0A:
undetectable
6fgdA-3aq0A:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 7 ASP A 107
ASP A 111
ARG A 116
LYS A 193
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.79A 6g31A-3aq0A:
25.6
6g31A-3aq0A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 5 ASP A 107
ASP A 111
ARG A 116
LYS A 193
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.79A 6g31C-3aq0A:
25.8
6g31C-3aq0A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 7 LEU A 104
ASP A 107
ASP A 111
ARG A 116
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
0.46A 6g31D-3aq0A:
25.0
6g31D-3aq0A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 4 LEU A 104
ASP A 107
ASP A 111
ARG A 116
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
0.43A 6g31E-3aq0A:
19.1
6g31E-3aq0A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 7 ASP A 107
ASP A 111
ARG A 116
LYS A 193
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
FPP  A1002 (-2.5A)
0.69A 6g31G-3aq0A:
24.8
6g31G-3aq0A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
3aq0 GERANYL DIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana)
4 / 6 LEU A 104
ASP A 107
ASP A 111
ARG A 116
None
MG  A1000 (-2.9A)
MG  A1001 (-2.8A)
FPP  A1002 (-2.9A)
0.69A 6g31J-3aq0A:
25.8
6g31J-3aq0A:
13.17