SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AX8_A_SAMA1474_0 (WBDD)	3aq4	ADP-RIBOSYLATION FACTOR 1 (Arabidopsis thaliana)	5 / 12	GLY A 29 ALA A 27 ILE A 33 VAL A 91 ILE A 89	GDP A 183 (-3.3A) GDP A 183 (-4.3A) None None None	0.87A	4ax8A-3aq4A: undetectable	4ax8A-3aq4A: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZT_A_SAMA1472_0 (METHYLTRANSFERASE WBDD)	3aq4	ADP-RIBOSYLATION FACTOR 1 (Arabidopsis thaliana)	5 / 12	GLY A 29 ALA A 27 ILE A 33 VAL A 91 ILE A 89	GDP A 183 (-3.3A) GDP A 183 (-4.3A) None None None	0.89A	4aztA-3aq4A: undetectable	4aztA-3aq4A: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZV_A_SAMA1474_0 (WBDD)	3aq4	ADP-RIBOSYLATION FACTOR 1 (Arabidopsis thaliana)	5 / 12	GLY A 29 ALA A 27 ILE A 33 VAL A 91 ILE A 89	GDP A 183 (-3.3A) GDP A 183 (-4.3A) None None None	0.87A	4azvA-3aq4A: 2.0	4azvA-3aq4A: 15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UW0_A_SAMA1506_0 (WBDD)	3aq4	ADP-RIBOSYLATION FACTOR 1 (Arabidopsis thaliana)	5 / 12	GLY A 29 ALA A 27 ILE A 33 VAL A 91 ILE A 89	GDP A 183 (-3.3A) GDP A 183 (-4.3A) None None None	0.96A	4uw0A-3aq4A: undetectable	4uw0A-3aq4A: 16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CZY_A_SAMA603_0 (LEGIONELLA EFFECTOR LEGAS4)	3aq4	ADP-RIBOSYLATION FACTOR 1 (Arabidopsis thaliana)	5 / 12	LEU A 145 GLY A 144 ARG A 104 SER A 94 LEU A 121	None	1.22A	5czyA-3aq4A: undetectable	5czyA-3aq4A: 15.98

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4AX8_A_SAMA1474_0","WBDD","3aq4","ADP-RIBOSYLATION FACTOR 1","Arabidopsis thaliana",5,"GLY A  29;ALA A  27;ILE A  33;VAL A  91;ILE A  89","GDP A 183 (-3.3A);GDP A 183 (-4.3A);None;None;None","0.87A","4ax8A-3aq4A:undetectable","4ax8A-3aq4A:15.04"],["4AZT_A_SAMA1472_0","METHYLTRANSFERASE WBDD","3aq4","ADP-RIBOSYLATION FACTOR 1","Arabidopsis thaliana",5,"GLY A  29;ALA A  27;ILE A  33;VAL A  91;ILE A  89","GDP A 183 (-3.3A);GDP A 183 (-4.3A);None;None;None","0.89A","4aztA-3aq4A:undetectable","4aztA-3aq4A:15.04"],["4AZV_A_SAMA1474_0","WBDD","3aq4","ADP-RIBOSYLATION FACTOR 1","Arabidopsis thaliana",5,"GLY A  29;ALA A  27;ILE A  33;VAL A  91;ILE A  89","GDP A 183 (-3.3A);GDP A 183 (-4.3A);None;None;None","0.87A","4azvA-3aq4A:2.0","4azvA-3aq4A:15.04"],["4UW0_A_SAMA1506_0","WBDD","3aq4","ADP-RIBOSYLATION FACTOR 1","Arabidopsis thaliana",5,"GLY A  29;ALA A  27;ILE A  33;VAL A  91;ILE A  89","GDP A 183 (-3.3A);GDP A 183 (-4.3A);None;None;None","0.96A","4uw0A-3aq4A:undetectable","4uw0A-3aq4A:16.50"],["5CZY_A_SAMA603_0","LEGIONELLA EFFECTOR LEGAS4","3aq4","ADP-RIBOSYLATION FACTOR 1","Arabidopsis thaliana",5,"LEU A 145;GLY A 144;ARG A 104;SER A  94;LEU A 121","None","1.22A","5czyA-3aq4A:undetectable","5czyA-3aq4A:15.98"]]