SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
HIS A 263
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.36A 1hrkA-3aqiA:
61.1		 1hrkA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 8 MET A  99
ARG A 114
LEU A 115
PRO A 266
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.34A 1hrkA-3aqiA:
61.1		 1hrkA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.38A 1hrkA-3aqiA:
61.1		 1hrkA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
HIS A 263
PRO A 266
VAL A 269
ARG A 272
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
FES  A 501 (-4.1A)
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.54A 1hrkB-3aqiA:
60.9		 1hrkB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 8 MET A  99
ARG A 114
LEU A 115
PRO A 266
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.37A 1hrkB-3aqiA:
60.9		 1hrkB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 101
PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.46A 1hrkB-3aqiA:
60.9		 1hrkB-3aqiA:
99.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_C_T44C128_1
(TRANSTHYRETIN)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 11 LEU A  74
ALA A 205
GLU A 178
ALA A 173
LEU A 169
 None
 1.06A 1ictA-3aqiA:
undetectable
1ictC-3aqiA:
undetectable		 1ictA-3aqiA:
14.16
1ictC-3aqiA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 6 THR A 338
GLN A 190
PHE A 377
PHE A 188
 None
 1.20A 1tt0A-3aqiA:
undetectable		 1tt0A-3aqiA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 6 THR A 338
GLN A 190
PHE A 377
PHE A 188
 None
 1.19A 1tt0B-3aqiA:
1.9		 1tt0B-3aqiA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 6 THR A 338
GLN A 190
PHE A 377
PHE A 188
 None
 1.19A 1tt0C-3aqiA:
undetectable		 1tt0C-3aqiA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 6 THR A 338
GLN A 190
PHE A 377
PHE A 188
 None
 1.20A 1tt0D-3aqiA:
2.4		 1tt0D-3aqiA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 7 ASP A  87
ARG A 164
LEU A 169
GLU A 171
 None
 0.82A 2cdqB-3aqiA:
1.5		 2cdqB-3aqiA:
22.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 ILE A 342
SER A 195
PRO A 266
VAL A 269
TRP A 310
 None
None
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 1.02A 2hrcA-3aqiA:
60.0		 2hrcA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
ILE A 119
SER A 197
HIS A 263
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
None
CHD  A   1 (-3.0A)
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.56A 2hrcA-3aqiA:
60.0		 2hrcA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 12 SER A 195
HIS A 263
LEU A 265
PRO A 266
VAL A 269
TRP A 310
 None
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 1.14A 2hrcA-3aqiA:
60.0		 2hrcA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 7 MET A  99
ARG A 114
LEU A 115
PRO A 266
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.26A 2hrcA-3aqiA:
60.0		 2hrcA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 7 MET A  99
LEU A  89
PRO A 266
TRP A 310
 CHD  A   2 (-4.0A)
None
CHD  A   2 ( 4.5A)
CHD  A   2 (-4.7A)
 1.22A 2hrcA-3aqiA:
60.0		 2hrcA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 101
PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.23A 2hrcA-3aqiA:
60.0		 2hrcA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_B_CHDB1603_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 5 MET A  99
ARG A 114
LEU A 115
PRO A 266
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
None
 0.47A 2hrcB-3aqiA:
60.7		 2hrcB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 101
PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.48A 2hrcB-3aqiA:
60.7		 2hrcB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
HIS A 263
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.42A 2hrcB-3aqiA:
60.7		 2hrcB-3aqiA:
99.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 HIS A 388
ILE A  71
LEU A  74
 None
 0.70A 2kceA-3aqiA:
undetectable		 2kceA-3aqiA:
20.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 12 LEU A 115
ILE A 119
HIS A 263
LEU A 265
PRO A 266
VAL A 269
 CHD  A   2 ( 4.8A)
None
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
 1.37A 2pnjA-3aqiA:
59.5		 2pnjA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  89
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
HIS A 263
LEU A 265
PRO A 266
VAL A 269
VAL A 305
 CHD  A   1 ( 3.8A)
None
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
 0.35A 2pnjA-3aqiA:
59.5		 2pnjA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 5 MET A  99
PRO A 266
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.14A 2pnjA-3aqiA:
59.5		 2pnjA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 ILE A 342
SER A 195
PRO A 266
VAL A 269
TRP A 310
 None
None
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 0.99A 2pnjB-3aqiA:
59.7		 2pnjB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
SER A 197
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-3.0A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.44A 2pnjB-3aqiA:
59.7		 2pnjB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 SER A 195
HIS A 263
PRO A 266
VAL A 269
TRP A 310
 None
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 1.14A 2pnjB-3aqiA:
59.7		 2pnjB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 7 MET A  99
ILE A 111
ARG A 114
PRO A 266
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.34A 2pnjB-3aqiA:
59.7		 2pnjB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 101
PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.37A 2pnjB-3aqiA:
59.7		 2pnjB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 ILE A 342
SER A 195
PRO A 266
VAL A 269
TRP A 310
 None
None
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 1.03A 2po5A-3aqiA:
60.6		 2po5A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
SER A 197
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-3.0A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.63A 2po5A-3aqiA:
60.6		 2po5A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 SER A 195
LEU A 265
PRO A 266
VAL A 269
TRP A 310
 None
None
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 1.16A 2po5A-3aqiA:
60.6		 2po5A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 8 MET A  99
LEU A 101
ARG A 114
LEU A 115
PRO A 266
VAL A 305
GLY A 306
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
 0.51A 2po5A-3aqiA:
60.6		 2po5A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		11 / 11 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
SER A 197
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
CHD  A   1 (-3.0A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.69A 2po5B-3aqiA:
60.3		 2po5B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 11 SER A 195
LEU A 265
PRO A 266
VAL A 269
TRP A 310
 None
None
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 1.17A 2po5B-3aqiA:
60.3		 2po5B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 8 MET A  99
LEU A 101
ARG A 114
LEU A 115
PRO A 266
VAL A 305
GLY A 306
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
 0.53A 2po5B-3aqiA:
60.3		 2po5B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 8 MET A  99
LEU A 101
LEU A  89
PRO A 266
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
None
CHD  A   2 ( 4.5A)
 0.88A 2po5B-3aqiA:
60.3		 2po5B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.25A 2po5B-3aqiA:
37.1		 2po5B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
ILE A 119
SER A 195
HIS A 263
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
None
None
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.45A 2po7A-3aqiA:
60.4		 2po7A-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO7_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		9 / 9 MET A  99
LEU A 101
ARG A 114
LEU A 115
PRO A 266
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.40A 2po7A-3aqiA:
60.4		 2po7A-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO7_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 9 MET A  99
LEU A 101
LEU A  89
PRO A 266
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
None
CHD  A   2 ( 4.5A)
CHD  A   2 (-4.7A)
 1.08A 2po7A-3aqiA:
60.4		 2po7A-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
SER A 195
HIS A 263
LEU A 265
PRO A 266
VAL A 269
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
None
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   2 (-4.7A)
 0.57A 2po7B-3aqiA:
60.0		 2po7B-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO7_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 9 LEU A  92
PRO A 266
VAL A 305
GLY A 306
TRP A 310
 CHD  A   1 (-4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
CHD  A   2 (-4.7A)
 1.32A 2po7B-3aqiA:
60.0		 2po7B-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO7_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		9 / 9 MET A  99
LEU A 101
ARG A 114
LEU A 115
PRO A 266
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.45A 2po7B-3aqiA:
60.0		 2po7B-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.20A 2po7B-3aqiA:
60.0		 2po7B-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 8 MET A  99
LEU A 101
PRO A 266
SER A 268
VAL A 305
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
None
 0.86A 2qd2A-3aqiA:
54.3		 2qd2A-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD2_B_CHDB1_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 10 MET A  99
LEU A 101
PRO A 266
SER A 268
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.78A 2qd2B-3aqiA:
53.8		 2qd2B-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 11 LEU A  89
LEU A  92
LEU A  98
ILE A 119
THR A 198
HIS A 263
VAL A 305
TRP A 310
 None
CHD  A   1 (-4.8A)
CHD  A   1 (-4.3A)
None
None
CHD  A   1 (-4.3A)
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.67A 2qd3A-3aqiA:
59.6		 2qd3A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 8 MET A  99
PRO A 266
SER A 268
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.36A 2qd3A-3aqiA:
59.6		 2qd3A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 6 MET A  99
ILE A 111
PRO A 266
SER A 268
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
None
 0.28A 2qd3B-3aqiA:
60.0		 2qd3B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		11 / 12 LEU A  92
PHE A  93
LEU A  98
GLN A 122
SER A 197
HIS A 263
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   1 ( 4.1A)
CHD  A   1 (-3.0A)
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.72A 2qd4A-3aqiA:
60.7		 2qd4A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 SER A 195
HIS A 263
LEU A 265
VAL A 269
TRP A 310
 None
CHD  A   1 (-4.3A)
None
None
CHD  A   2 (-4.7A)
 1.27A 2qd4A-3aqiA:
60.7		 2qd4A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD4_A_CHDA802_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 6 MET A  99
ARG A 114
PRO A 266
VAL A 305
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
None
 0.66A 2qd4A-3aqiA:
60.7		 2qd4A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 5 LEU A 101
PRO A 102
LEU A 107
ILE A 111
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
 0.73A 2qd4A-3aqiA:
60.7		 2qd4A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD4_B_CHDB926_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		9 / 10 MET A  99
LEU A 101
ILE A 111
ARG A 114
PRO A 266
SER A 268
VAL A 305
GLY A 306
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
 0.52A 2qd4B-3aqiA:
60.6		 2qd4B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   2 (-3.6A)
 0.44A 2qd4B-3aqiA:
60.6		 2qd4B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		11 / 12 LEU A  92
PHE A  93
LEU A  98
MET A  99
GLN A 122
HIS A 263
LEU A 265
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
CHD  A   1 ( 4.1A)
CHD  A   1 (-4.3A)
None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.41A 2qd4B-3aqiA:
60.6		 2qd4B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 8 MET A  99
LEU A 101
PRO A 266
SER A 268
VAL A 305
GLY A 306
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
 0.74A 2qd5A-3aqiA:
53.6		 2qd5A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   2 (-3.6A)
 0.52A 2qd5A-3aqiA:
53.6		 2qd5A-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 8 MET A  99
LEU A 101
ARG A 114
PRO A 266
SER A 268
VAL A 305
GLY A 306
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
 0.80A 2qd5B-3aqiA:
53.6		 2qd5B-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.47A 2qd5B-3aqiA:
53.6		 2qd5B-3aqiA:
99.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 7 GLN A 193
VAL A 284
ILE A 335
ALA A 262
THR A 283
 None
 1.27A 2xrzB-3aqiA:
undetectable		 2xrzB-3aqiA:
21.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 11 ILE A 342
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 None
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 1.17A 3aqiA-3aqiA:
63.2		 3aqiA-3aqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		11 / 11 MET A  76
LEU A  92
PHE A  93
MET A  99
ILE A 119
SER A 197
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-3.0A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.49A 3aqiA-3aqiA:
63.2		 3aqiA-3aqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 6 MET A  99
ARG A 114
PRO A 266
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.00A 3aqiA-3aqiA:
63.2		 3aqiA-3aqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.00A 3aqiA-3aqiA:
63.2		 3aqiA-3aqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 6 MET A  99
ARG A 114
PRO A 266
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.40A 3aqiB-3aqiA:
61.5		 3aqiB-3aqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.51A 3aqiB-3aqiA:
61.5		 3aqiB-3aqiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
SER A 197
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-3.0A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.30A 3aqiB-3aqiA:
61.5		 3aqiB-3aqiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 LEU A 371
ASN A 374
ALA A 382
THR A 283
VAL A 287
 None
 0.79A 3c6gA-3aqiA:
undetectable		 3c6gA-3aqiA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 LEU A 371
ASN A 374
ALA A 382
THR A 283
VAL A 287
 None
 0.81A 3c6gB-3aqiA:
undetectable		 3c6gB-3aqiA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 LEU A 371
ASN A 374
ALA A 382
THR A 283
VAL A 287
 None
 0.80A 3czhB-3aqiA:
undetectable		 3czhB-3aqiA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 6 TYR A 191
GLY A 162
THR A 189
GLU A 172
 None
 1.03A 3fpjA-3aqiA:
undetectable		 3fpjA-3aqiA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 THR A 338
TYR A 194
LEU A 203
ILE A 206
THR A 170
 None
 1.32A 3frqA-3aqiA:
undetectable		 3frqA-3aqiA:
22.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 7 MET A  99
LEU A 101
PRO A 266
SER A 268
GLY A 306
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   2 ( 3.8A)
 0.89A 3hcnA-3aqiA:
54.1		 3hcnA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCN_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 9 MET A  99
LEU A 101
ARG A 114
PRO A 266
SER A 268
VAL A 305
GLY A 306
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
 1.01A 3hcnB-3aqiA:
54.5		 3hcnB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCN_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 9 MET A  99
LEU A 101
PRO A 266
SER A 268
VAL A 305
GLY A 306
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
 0.87A 3hcnB-3aqiA:
54.5		 3hcnB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.65A 3hcnB-3aqiA:
54.5		 3hcnB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 101
PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.80A 3hcoA-3aqiA:
54.0		 3hcoA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCO_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 9 MET A  99
LEU A 101
PRO A 266
SER A 268
VAL A 305
GLY A 306
PRO A 307
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
None
 0.76A 3hcoA-3aqiA:
54.0		 3hcoA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 101
PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.49A 3hcoB-3aqiA:
54.4		 3hcoB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 10 MET A  99
LEU A 101
ARG A 114
PRO A 266
SER A 268
VAL A 305
GLY A 306
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
 0.90A 3hcoB-3aqiA:
54.4		 3hcoB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCO_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 10 MET A  99
LEU A 101
PRO A 266
SER A 268
VAL A 305
GLY A 306
PRO A 307
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
None
 0.69A 3hcoB-3aqiA:
54.4		 3hcoB-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCP_A_CHDA2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 9 LEU A 101
ARG A 114
PRO A 266
SER A 268
GLY A 306
PRO A 307
MET A 308
TRP A 310
 CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   2 ( 3.8A)
None
None
CHD  A   2 (-4.7A)
 0.89A 3hcpA-3aqiA:
59.9		 3hcpA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCP_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		9 / 10 MET A  99
LEU A 101
ILE A 111
ARG A 114
PRO A 266
SER A 268
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.61A 3hcpB-3aqiA:
60.5		 3hcpB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCP_B_CHDB4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 GLY A 127
PRO A 131
LEU A 345
 GOL  A 424 (-4.2A)
GOL  A 424 ( 4.8A)
None
 0.12A 3hcpB-3aqiA:
60.5		 3hcpB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 8 LEU A 101
ARG A 114
PRO A 266
GLY A 306
 CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 3.8A)
 0.78A 3hcrA-3aqiA:
53.5		 3hcrA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 8 LEU A 101
PRO A 266
GLY A 306
PRO A 307
 CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 3.8A)
None
 0.62A 3hcrA-3aqiA:
53.5		 3hcrA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 8 PRO A 266
SER A 268
GLY A 306
PRO A 307
MET A 308
 CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   2 ( 3.8A)
None
None
 0.25A 3hcrA-3aqiA:
53.5		 3hcrA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.47A 3hcrA-3aqiA:
53.5		 3hcrA-3aqiA:
99.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 7 LEU A 101
ARG A 114
PRO A 266
SER A 268
GLY A 306
MET A 308
 CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   2 ( 3.8A)
None
 0.83A 3hcrB-3aqiA:
53.6		 3hcrB-3aqiA:
99.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 8 ASP A 274
GLN A 193
PRO A 192
TYR A 191
 None
 1.10A 3oyaA-3aqiA:
undetectable		 3oyaA-3aqiA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_0
(2'-O-METHYL
TRANSFERASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 ASN A 374
GLY A 142
GLY A 373
LEU A 147
ASP A 148
 None
 1.46A 3r24A-3aqiA:
2.4		 3r24A-3aqiA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 TYR A 191
MET A  99
LEU A  92
 None
CHD  A   2 (-4.0A)
CHD  A   1 (-4.8A)
 0.70A 3vw1D-3aqiA:
undetectable		 3vw1D-3aqiA:
19.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		12 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
MET A  99
ILE A 119
SER A 197
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   2 (-4.0A)
None
CHD  A   1 (-3.0A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.43A 3w1wA-3aqiA:
60.5		 3w1wA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_A_CHDA1503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 8 MET A  99
ILE A 111
ARG A 114
LEU A 115
VAL A 305
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.26A 3w1wA-3aqiA:
60.5		 3w1wA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 PRO A 102
LEU A 107
ILE A 111
ARG A 114
 CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
 0.41A 3w1wA-3aqiA:
60.5		 3w1wA-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_A_SALA1505_1
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 9 VAL A 270
PRO A 277
SER A 281
TRP A 301
LEU A 311
 None
 0.19A 3w1wA-3aqiA:
60.5
3w1wB-3aqiA:
60.3		 3w1wA-3aqiA:
99.72
3w1wB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		9 / 9 MET A  99
ILE A 111
ARG A 114
LEU A 115
PRO A 266
SER A 268
GLY A 306
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.8A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   2 ( 3.8A)
None
CHD  A   2 (-4.7A)
 0.33A 3w1wB-3aqiA:
60.3		 3w1wB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.38A 3w1wB-3aqiA:
60.3		 3w1wB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		11 / 12 MET A  76
LEU A  92
PHE A  93
LEU A  98
ILE A 119
GLN A 122
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
None
CHD  A   1 ( 4.1A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.41A 3w1wB-3aqiA:
60.3		 3w1wB-3aqiA:
99.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 12 MET A  76
LEU A  98
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
GLU A 343
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.3A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
None
 0.96A 3w1wB-3aqiA:
60.3		 3w1wB-3aqiA:
99.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 ASN A 408
ASP A  97
ASN A 204
 None
 0.77A 4agaA-3aqiA:
undetectable		 4agaA-3aqiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 348
GLU A 351
SER A 353
 None
 0.67A 4ccqA-3aqiA:
undetectable		 4ccqA-3aqiA:
22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 12 LEU A  89
LEU A  92
LEU A  98
ILE A 119
GLN A 122
THR A 198
HIS A 263
VAL A 305
 None
CHD  A   1 (-4.8A)
CHD  A   1 (-4.3A)
None
CHD  A   1 ( 4.1A)
None
CHD  A   1 (-4.3A)
CHD  A   1 ( 4.9A)
 0.60A 4f4dA-3aqiA:
60.3		 4f4dA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 7 MET A  99
ILE A 111
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.32A 4f4dA-3aqiA:
60.3		 4f4dA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 8 MET A  99
ILE A 111
PRO A 266
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   2 ( 4.5A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.21A 4f4dB-3aqiA:
60.7		 4f4dB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 101
PRO A 102
LEU A 107
ILE A 111
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 ( 4.7A)
 0.34A 4f4dB-3aqiA:
60.7		 4f4dB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		9 / 12 LEU A  89
LEU A  92
LEU A  98
ILE A 119
SER A 197
THR A 198
HIS A 263
VAL A 305
TRP A 310
 None
CHD  A   1 (-4.8A)
CHD  A   1 (-4.3A)
None
CHD  A   1 (-3.0A)
None
CHD  A   1 (-4.3A)
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.45A 4f4dB-3aqiA:
60.7		 4f4dB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 12 LEU A  89
LEU A  92
LEU A  98
LYS A 118
ILE A 119
SER A 197
VAL A 305
TRP A 310
 None
CHD  A   1 (-4.8A)
CHD  A   1 (-4.3A)
None
None
CHD  A   1 (-3.0A)
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.93A 4f4dB-3aqiA:
60.7		 4f4dB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KLA_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 7 MET A  99
LYS A 118
SER A 268
MET A 308
 CHD  A   2 (-4.0A)
None
CHD  A   2 ( 4.4A)
None
 1.16A 4klaA-3aqiA:
59.2		 4klaA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KLA_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 7 MET A  99
SER A 268
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.29A 4klaA-3aqiA:
59.2		 4klaA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KLA_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 5 MET A  99
ARG A 114
PRO A 266
MET A 308
 CHD  A   2 (-4.0A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
None
 0.57A 4klaB-3aqiA:
59.2		 4klaB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 7 LEU A 101
ARG A 114
PRO A 266
SER A 268
VAL A 305
MET A 308
 CHD  A   3 ( 4.9A)
CHD  A   2 (-3.6A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
None
 0.91A 4klrA-3aqiA:
53.6		 4klrA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 5 LEU A 101
PRO A 102
LEU A 107
ILE A 111
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 ( 4.7A)
 0.52A 4klrA-3aqiA:
53.6		 4klrA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 8 LEU A 101
PRO A 266
SER A 268
GLY A 306
 CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   2 ( 3.8A)
 0.73A 4klrB-3aqiA:
52.9		 4klrB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 7 MET A  99
PRO A 266
SER A 268
VAL A 305
MET A 308
TRP A 310
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
CHD  A   1 ( 4.9A)
None
CHD  A   2 (-4.7A)
 0.29A 4kmmA-3aqiA:
59.7		 4kmmA-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 5 MET A  99
LEU A 101
PRO A 266
SER A 268
 CHD  A   2 (-4.0A)
CHD  A   3 ( 4.9A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
 0.46A 4kmmB-3aqiA:
59.5		 4kmmB-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		8 / 10 LEU A  89
LEU A  92
LEU A  98
ILE A 119
THR A 198
HIS A 263
VAL A 305
TRP A 310
 None
CHD  A   1 (-4.8A)
CHD  A   1 (-4.3A)
None
None
CHD  A   1 (-4.3A)
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.54A 4mk4A-3aqiA:
59.3		 4mk4A-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 10 LEU A  89
LEU A  92
LEU A  98
LYS A 118
ILE A 119
VAL A 305
TRP A 310
 None
CHD  A   1 (-4.8A)
CHD  A   1 (-4.3A)
None
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 1.10A 4mk4A-3aqiA:
59.3		 4mk4A-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		7 / 8 MET A  99
PRO A 266
SER A 268
VAL A 269
ARG A 272
VAL A 305
GLY A 306
 CHD  A   2 (-4.0A)
CHD  A   2 ( 4.5A)
CHD  A   2 ( 4.4A)
None
FES  A 501 (-4.1A)
CHD  A   1 ( 4.9A)
CHD  A   2 ( 3.8A)
 0.33A 4mk4A-3aqiA:
59.3		 4mk4A-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 6 PHE A  93
MET A  99
ILE A 111
ARG A 114
VAL A 305
 CHD  A   1 ( 4.7A)
CHD  A   2 (-4.0A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
CHD  A   1 ( 4.9A)
 0.59A 4mk4B-3aqiA:
59.3		 4mk4B-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		9 / 11 MET A  76
LEU A  92
PHE A  93
LEU A  98
HIS A 263
PRO A 266
VAL A 269
VAL A 305
TRP A 310
 CHD  A   1 ( 3.8A)
CHD  A   1 (-4.8A)
CHD  A   1 ( 4.7A)
CHD  A   1 (-4.3A)
CHD  A   1 (-4.3A)
CHD  A   2 ( 4.5A)
None
CHD  A   1 ( 4.9A)
CHD  A   2 (-4.7A)
 0.27A 4mk4B-3aqiA:
59.3		 4mk4B-3aqiA:
99.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 LEU A 107
ILE A 111
ARG A 114
 CHD  A   3 ( 4.6A)
CHD  A   2 ( 4.7A)
CHD  A   2 (-3.6A)
 0.65A 4mk4B-3aqiA:
59.3		 4mk4B-3aqiA:
99.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 3aqi FERROCHELATASE
(Homo
sapiens) 		5 / 12 MET A  73
LEU A  74
THR A 136
ILE A 161
PHE A 163
 None
 1.49A 4udcA-3aqiA:
undetectable		 4udcA-3aqiA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 3aqi FERROCHELATASE
(Homo
sapiens) 		4 / 4 LEU A 147
ILE A 389
HIS A 386
VAL A 385
 None
 1.30A 4xyzA-3aqiA:
undetectable		 4xyzA-3aqiA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		6 / 12 PRO A 131
TRP A 135
GLY A  77
THR A 136
ILE A 126
ILE A 342
 GOL  A 424 ( 4.8A)
None
None
None
None
None
 1.31A 6emuA-3aqiA:
3.4		 6emuA-3aqiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 HIS A 388
ARG A 184
ILE A 186
 None
 0.86A 6fgdA-3aqiA:
6.4		 6fgdA-3aqiA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3aqi FERROCHELATASE
(Homo
sapiens) 		3 / 3 ASP A  95
LEU A  98
ARG A 272
 None
CHD  A   1 (-4.3A)
FES  A 501 (-4.1A)
 0.83A 7dfrA-3aqiA:
undetectable		 7dfrA-3aqiA:
18.05