SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aqs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 LEU A 114
GLY A 109
LEU A 175
SER A 174
 None
 0.96A 3aiaA-3aqsA:
undetectable		 3aiaA-3aqsA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 LEU A  35
SER A  38
LEU A  42
LEU A  77
 None
 0.97A 3f33A-3aqsA:
undetectable		 3f33A-3aqsA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 8 LEU A 175
SER A 174
ILE A 179
PHE A 128
 None
 0.70A 3ln1A-3aqsA:
undetectable		 3ln1A-3aqsA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 7 LEU A 175
SER A 174
ILE A 179
PHE A 128
 None
 0.70A 3ln1B-3aqsA:
undetectable		 3ln1B-3aqsA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 PHE A 128
ALA A 134
GLY A 173
LEU A 138
 None
 0.88A 4dubA-3aqsA:
undetectable		 4dubA-3aqsA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 6 PHE A 128
ALA A 134
GLY A 173
LEU A 138
 None
 0.86A 4dubB-3aqsA:
undetectable		 4dubB-3aqsA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 7 PHE A 128
ALA A  85
LEU A 142
LEU A 138
 None
 0.91A 4ejgC-3aqsA:
undetectable		 4ejgC-3aqsA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		3 / 3 PHE A 159
VAL A 207
GLU A 211
 None
 0.83A 4fvqA-3aqsA:
undetectable		 4fvqA-3aqsA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 8 PHE A 159
ARG A 203
ALA A 212
LEU A 202
 None
 0.97A 4rkuA-3aqsA:
undetectable
4rkuJ-3aqsA:
undetectable		 4rkuA-3aqsA:
15.26
4rkuJ-3aqsA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 7 PHE A 159
ARG A 203
ALA A 212
LEU A 202
 None
 1.01A 4xk8A-3aqsA:
undetectable		 4xk8A-3aqsA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		4 / 8 PHE A 159
ARG A 203
ALA A 212
LEU A 202
 None
 1.02A 4xk8a-3aqsA:
undetectable		 4xk8a-3aqsA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		5 / 11 ILE A  56
VAL A  51
GLU A  75
ASP A  73
ALA A  80
 None
 1.13A 5lg3A-3aqsA:
3.1		 5lg3A-3aqsA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 3aqs BACTERIAL REGULATORY
PROTEINS, TETR
FAMILY
(Corynebacterium
glutamicum) 		3 / 3 ARG A 116
PHE A  86
LEU A  93
 None
 0.87A 5veuA-3aqsA:
undetectable		 5veuA-3aqsA:
19.92