SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aqu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 VAL A 229
VAL A   3
TRP A 178
 None
 0.99A 1av2A-3aquA:
undetectable
1av2B-3aquA:
undetectable		 1av2A-3aquA:
4.41
1av2B-3aquA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 12 SER A  22
VAL A  17
LEU A  28
THR A  68
TRP A   9
 None
 1.12A 1dmyB-3aquA:
undetectable		 1dmyB-3aquA:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		6 / 9 TYR A   8
PHE A  32
GLY A  74
ASP A 114
ASP A 185
TRP A 324
 None
 0.96A 1e9lA-3aquA:
44.8		 1e9lA-3aquA:
30.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		7 / 9 TYR A   8
PHE A  32
GLY A  74
ASP A 114
MET A 182
TYR A 184
ASP A 185
 None
 0.77A 1e9lA-3aquA:
44.8		 1e9lA-3aquA:
30.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 12 GLU A 141
ILE A 100
LEU A 111
GLY A 110
ALA A  33
 None
 1.31A 1hvyB-3aquA:
undetectable		 1hvyB-3aquA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKV_A_EFZA2000_1
(POL POLYPROTEIN)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 9 LEU A 130
VAL A  42
TYR A  82
TRP A 115
LEU A 113
 None
 1.48A 1ikvA-3aquA:
undetectable		 1ikvA-3aquA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKW_A_EFZA2000_1
(POL POLYPROTEIN)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A  42
TYR A  82
TRP A 115
LEU A 113
 None
 1.44A 1ikwA-3aquA:
undetectable		 1ikwA-3aquA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 7 PHE A  29
VAL A 229
TRP A 178
ASN A 180
 None
 1.14A 1jqdA-3aquA:
undetectable		 1jqdA-3aquA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 12 TYR A 312
SER A 210
SER A 159
ALA A 228
ILE A 219
 None
 1.21A 1nt2A-3aquA:
undetectable		 1nt2A-3aquA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 VAL A 229
VAL A   3
TRP A 178
 None
 0.84A 1w5uA-3aquA:
undetectable
1w5uB-3aquA:
undetectable		 1w5uA-3aquA:
4.41
1w5uB-3aquA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		10 / 11 TYR A   8
PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.54A 2a3aA-3aquA:
41.3		 2a3aA-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 9 GLY A  75
GLU A 116
MET A 182
TYR A 184
TRP A 324
 None
 1.21A 2a3aB-3aquA:
41.5		 2a3aB-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		8 / 9 PHE A  32
GLY A  74
GLU A 116
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.43A 2a3aB-3aquA:
41.5		 2a3aB-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		8 / 11 TYR A   8
PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
TRP A 324
 None
 0.68A 2a3bA-3aquA:
41.3		 2a3bA-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		9 / 11 TYR A   8
PHE A  32
GLY A  74
ASP A 114
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.50A 2a3bA-3aquA:
41.3		 2a3bA-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		8 / 10 PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
ASP A 185
TRP A 324
 None
 0.61A 2a3bB-3aquA:
41.4		 2a3bB-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		8 / 10 PHE A  32
GLY A  74
ASP A 114
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.36A 2a3bB-3aquA:
41.4		 2a3bB-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		9 / 12 TYR A   8
PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
ASP A 185
TRP A 324
 None
 0.69A 2a3cA-3aquA:
41.2		 2a3cA-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		9 / 12 TYR A   8
PHE A  32
GLY A  74
ASP A 114
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.50A 2a3cA-3aquA:
41.2		 2a3cA-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		8 / 12 PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
ASP A 185
TRP A 324
 None
 0.62A 2a3cB-3aquA:
41.5		 2a3cB-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		8 / 12 PHE A  32
GLY A  74
ASP A 114
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.38A 2a3cB-3aquA:
41.5		 2a3cB-3aquA:
27.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 LYS A 309
ASP A 185
ASP A 261
 None
 0.88A 2br4A-3aquA:
undetectable		 2br4A-3aquA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 12 TYR A 290
ALA A 238
PRO A 198
GLY A 188
GLY A 262
 FLC  A 356 (-4.6A)
None
None
None
None
 1.04A 2igtA-3aquA:
undetectable		 2igtA-3aquA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 12 TYR A 290
ALA A 238
PRO A 198
GLY A 188
GLY A 262
 FLC  A 356 (-4.6A)
None
None
None
None
 1.06A 2igtB-3aquA:
undetectable		 2igtB-3aquA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 TRP A 218
ALA A 155
VAL A 179
 None
 0.82A 2izqA-3aquA:
undetectable
2izqB-3aquA:
undetectable		 2izqA-3aquA:
4.41
2izqB-3aquA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 VAL A   3
TRP A 178
VAL A 229
 None
 0.89A 2izqC-3aquA:
undetectable
2izqD-3aquA:
undetectable		 2izqC-3aquA:
4.41
2izqD-3aquA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 6 ALA A 154
ASP A 112
TRP A 134
MET A 124
 None
 1.40A 2ouzA-3aquA:
undetectable		 2ouzA-3aquA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 5 VAL A 307
THR A 308
VAL A 287
GLY A 288
 None
 1.09A 2p2fA-3aquA:
undetectable		 2p2fA-3aquA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 4 VAL A 307
THR A 308
VAL A 287
GLY A 288
 None
 1.14A 2p2fB-3aquA:
undetectable		 2p2fB-3aquA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		7 / 9 TYR A   8
PHE A  32
GLY A  74
ASP A 114
GLU A 116
TYR A 184
TRP A 324
 None
 0.79A 2uy4A-3aquA:
18.8		 2uy4A-3aquA:
25.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		7 / 11 TYR A   8
PHE A  32
GLY A  74
ASP A 114
GLU A 116
TYR A 184
TRP A 324
 None
 0.95A 2xtkA-3aquA:
19.5		 2xtkA-3aquA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		7 / 10 TYR A   8
PHE A  32
GLY A  74
ASP A 114
GLU A 116
TYR A 184
TRP A 324
 None
 0.85A 2xtkB-3aquA:
19.7		 2xtkB-3aquA:
23.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		10 / 11 TYR A   8
PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.56A 3g6mA-3aquA:
41.4		 3g6mA-3aquA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA427_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 5 TYR A 117
MET A 182
ASP A 185
TRP A 191
 None
 0.69A 3g6mA-3aquA:
41.4		 3g6mA-3aquA:
30.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 LEU A 181
LEU A 230
ARG A 316
 None
 0.59A 3hcnB-3aquA:
undetectable		 3hcnB-3aquA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 12 TYR A 312
ALA A 213
SER A 159
ALA A 228
ILE A 219
 None
 1.18A 3id6C-3aquA:
undetectable		 3id6C-3aquA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 ALA A 155
VAL A 179
TRP A 218
 None
 0.79A 3l8lA-3aquA:
undetectable
3l8lB-3aquA:
undetectable		 3l8lA-3aquA:
4.41
3l8lB-3aquA:
3.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		3 / 3 ASN A 296
ALA A 257
ARG A 240
 None
 0.90A 3tj7C-3aquA:
undetectable
3tj7D-3aquA:
undetectable		 3tj7C-3aquA:
19.37
3tj7D-3aquA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		7 / 11 GLY A  75
GLU A 116
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 1.09A 3wqvA-3aquA:
43.9		 3wqvA-3aquA:
27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		9 / 11 PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.71A 3wqvA-3aquA:
43.9		 3wqvA-3aquA:
27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		7 / 11 GLY A  75
GLU A 116
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 1.09A 3wqwA-3aquA:
44.0		 3wqwA-3aquA:
27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		9 / 11 PHE A  32
GLY A  74
ASP A 114
GLU A 116
MET A 182
TYR A 184
ASP A 185
TYR A 235
TRP A 324
 None
 0.73A 3wqwA-3aquA:
44.0		 3wqwA-3aquA:
27.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 5 GLN A 340
SER A 339
ASP A  21
ASP A  19
 None
 1.45A 4qtuB-3aquA:
undetectable		 4qtuB-3aquA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 4 PHE A  32
ASP A 112
GLY A  74
SER A  71
 None
 1.36A 4xp9C-3aquA:
undetectable		 4xp9C-3aquA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 8 GLY A  75
GLU A 116
TYR A 184
ASP A 185
TRP A 324
 None
 1.35A 5gqbA-3aquA:
41.1		 5gqbA-3aquA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		6 / 8 PHE A  32
GLY A  74
GLU A 116
TYR A 184
ASP A 185
TRP A 324
 None
 0.56A 5gqbA-3aquA:
41.1		 5gqbA-3aquA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 6 LEU A 176
VAL A 179
LEU A 223
VAL A 156
 None
 0.91A 5x7zA-3aquA:
undetectable		 5x7zA-3aquA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A  42
TYR A  82
TRP A 115
LEU A 113
 None
 1.41A 6bsgA-3aquA:
undetectable		 6bsgA-3aquA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A  42
TYR A  82
TRP A 115
LEU A 113
 None
 1.36A 6bsiA-3aquA:
undetectable		 6bsiA-3aquA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 10 LEU A 130
VAL A  42
TYR A  82
TRP A 115
LEU A 113
 None
 1.42A 6bsjA-3aquA:
undetectable		 6bsjA-3aquA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		4 / 6 TYR A 321
ASP A 329
VAL A 326
ALA A 341
 None
 1.02A 6djzB-3aquA:
undetectable		 6djzB-3aquA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F8C_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 6 ALA A 251
SER A 192
GLY A 188
ILE A 298
PHE A 272
 None
 1.26A 6f8cA-3aquA:
undetectable		 6f8cA-3aquA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)		 3aqu AT4G19810
(Arabidopsis
thaliana) 		5 / 11 PHE A  52
ASN A 180
LEU A 111
GLY A 110
PHE A 108
 None
 1.21A 6r2eG-3aquA:
undetectable		 6r2eG-3aquA:
20.05