SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3asi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 12 ILE A 905
GLN A 895
PHE A 896
LEU A1016
ALA A1017
HIS A 926
 None
 1.24A 1fbyA-3asiA:
undetectable		 1fbyA-3asiA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 LEU A 931
ASN A 982
ARG A 958
 None
 0.81A 2qhfA-3asiA:
undetectable		 2qhfA-3asiA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1170
ASP A1192
SER A1231
ILE A1117
LEU A1143
 None
 1.02A 3drcA-3asiA:
undetectable		 3drcA-3asiA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 9 ASP A 930
ASN A 913
GLY A 912
ASP A 914
ASP A 911
 None
 1.47A 3sfuA-3asiA:
undetectable		 3sfuA-3asiA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 GLN A1064
PHE A1068
GLY A1067
GLY A1059
ASN A1083
 None
 1.31A 3v3nA-3asiA:
undetectable		 3v3nA-3asiA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 GLN A1064
PHE A1068
GLY A1067
GLY A1059
ASN A1083
 None
 1.31A 3v3nD-3asiA:
undetectable		 3v3nD-3asiA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 GLN A1064
PHE A1068
GLY A1067
GLY A1059
ASN A1083
 None
 1.27A 3v3oB-3asiA:
undetectable		 3v3oB-3asiA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 9 GLY A 910
LEU A 983
ASN A 913
ASN A 908
ILE A 916
 None
 1.40A 3wdmA-3asiA:
undetectable		 3wdmA-3asiA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 9 GLY A 910
LEU A 983
ASP A 930
ASN A 913
ILE A 916
 None
 1.21A 3wdmA-3asiA:
undetectable		 3wdmA-3asiA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 9 GLY A 910
LEU A 983
ASP A 930
ASN A 913
ILE A 916
 None
 1.17A 3wdmC-3asiA:
undetectable		 3wdmC-3asiA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 GLN A1064
PHE A1068
GLY A1067
GLY A1059
ASN A1083
 None
 1.22A 4a6nA-3asiA:
undetectable		 4a6nA-3asiA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 GLN A1064
PHE A1068
GLY A1067
GLY A1059
ASN A1083
 None
 1.38A 4a99D-3asiA:
undetectable		 4a99D-3asiA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1170
ASP A1192
SER A1231
ILE A1117
LEU A1143
 None
 1.02A 4dfrA-3asiA:
undetectable		 4dfrA-3asiA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 ARG A1258
ILE A1098
PHE A1091
LEU A1241
 None
 0.89A 4mmcA-3asiA:
undetectable		 4mmcA-3asiA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		6 / 11 ILE A 905
GLN A 895
PHE A 896
LEU A1016
ALA A1017
HIS A 926
 None
 1.32A 4nqaA-3asiA:
undetectable		 4nqaA-3asiA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A 905
GLN A 895
LEU A1016
ALA A1017
HIS A 926
 None
 1.06A 4nqaH-3asiA:
undetectable		 4nqaH-3asiA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_1
(PROTEASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 GLY A1118
ILE A1217
VAL A1152
VAL A1240
ILE A1215
 None
 0.97A 4q5mA-3asiA:
undetectable		 4q5mA-3asiA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1170
ASP A1192
SER A1231
ILE A1117
LEU A1143
 None
 0.97A 4qi9A-3asiA:
undetectable		 4qi9A-3asiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1170
ASP A1192
SER A1231
ILE A1117
LEU A1143
 None
 1.04A 4qi9B-3asiA:
undetectable		 4qi9B-3asiA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 11 ILE A1170
ASP A1192
SER A1231
ILE A1117
LEU A1143
 None
 1.04A 4qleB-3asiA:
undetectable		 4qleB-3asiA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 9 ILE A1098
PHE A1091
GLY A1096
ILE A1253
ALA A1252
 None
 1.38A 4yp2B-3asiA:
undetectable		 4yp2B-3asiA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 9 ILE A1098
PHE A1091
GLY A1096
ILE A1253
ALA A1252
 None
 1.39A 5cf9B-3asiA:
undetectable		 5cf9B-3asiA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		5 / 12 ILE A1170
ASP A1192
SER A1231
ILE A1117
LEU A1143
 None
 0.99A 5hi6A-3asiA:
undetectable		 5hi6A-3asiA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 ILE A1170
HIS A1144
LEU A1128
ALA A1126
 None
 0.87A 5hrqE-3asiA:
undetectable
5hrqF-3asiA:
undetectable
5hrqJ-3asiA:
undetectable		 5hrqE-3asiA:
4.32
5hrqF-3asiA:
8.37
5hrqJ-3asiA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		3 / 3 ARG A1024
PHE A 894
LEU A 989
 None
 0.56A 5x1bC-3asiA:
undetectable		 5x1bC-3asiA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 6 PHE A1209
ARG A1182
ASN A1236
ASP A1113
 None
 1.28A 6dhbA-3asiA:
undetectable		 6dhbA-3asiA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3asi NEUREXIN-1-ALPHA
(Bos
taurus) 		4 / 7 ALA A1008
GLU A 919
ILE A 905
ILE A 991
 None
 0.92A 6fbnA-3asiA:
undetectable		 6fbnA-3asiA:
22.51