SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3asm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 8 GLY A 269
ILE A 271
VAL A 272
PRO A 265
 None
 0.97A 1rxcB-3asmA:
undetectable		 1rxcB-3asmA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A 269
ILE A 271
VAL A 272
PRO A 265
 None
 1.08A 1rxcD-3asmA:
undetectable		 1rxcD-3asmA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A 269
ILE A 271
VAL A 272
PRO A 265
 None
 0.97A 1rxcF-3asmA:
undetectable		 1rxcF-3asmA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 8 GLY A 269
ILE A 271
VAL A 272
PRO A 265
 None
 0.97A 1rxcK-3asmA:
undetectable		 1rxcK-3asmA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A 269
ILE A 271
VAL A 272
PRO A 265
 None
 0.97A 1rxcL-3asmA:
undetectable		 1rxcL-3asmA:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		5 / 10 ILE A 201
LYS A 176
VAL A 110
LEU A 184
TYR A 210
 None
 1.19A 1s1uA-3asmA:
2.7		 1s1uA-3asmA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		5 / 11 VAL A 109
VAL A 248
TYR A 247
GLU A  98
ILE A 244
 None
 1.34A 1t6zB-3asmA:
undetectable		 1t6zB-3asmA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		5 / 12 ILE A  94
GLY A  95
ALA A 231
ALA A 240
ILE A 201
 None
 1.05A 3jb1A-3asmA:
undetectable		 3jb1A-3asmA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_A_TPFA490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		5 / 8 PHE A 105
TYR A 104
ALA A 275
ALA A 277
LEU A 303
 None
 1.42A 3l4dA-3asmA:
undetectable		 3l4dA-3asmA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 6 ILE A 146
ILE A 201
GLY A  95
VAL A  99
 None
 0.95A 3n3iA-3asmA:
undetectable		 3n3iA-3asmA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A  74
LEU A  52
LEU A  33
 None
 0.70A 3ohtA-3asmA:
undetectable		 3ohtA-3asmA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A  74
LEU A  52
LEU A  33
 None
 0.71A 3ohtB-3asmA:
undetectable		 3ohtB-3asmA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 7 LYS A 176
VAL A 110
LEU A 184
TYR A 210
 None
 0.94A 4b3qA-3asmA:
4.3		 4b3qA-3asmA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 8 GLY A 269
ILE A 271
VAL A 272
PRO A 265
 None
 0.94A 4e1vA-3asmA:
undetectable		 4e1vA-3asmA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A 269
ILE A 271
VAL A 272
PRO A 265
 None
 0.99A 4e1vB-3asmA:
undetectable		 4e1vB-3asmA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		3 / 3 ILE A 221
ASP A 189
ARG A 224
 None
 0.84A 4pstA-3asmA:
undetectable		 4pstA-3asmA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 6 ILE A 201
PHE A 204
ARG A 182
THR A 155
 None
 1.02A 5b1aN-3asmA:
undetectable
5b1aW-3asmA:
undetectable		 5b1aN-3asmA:
19.81
5b1aW-3asmA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		3 / 3 GLU A 232
HIS A 235
VAL A 238
 None
 0.78A 5trqB-3asmA:
undetectable		 5trqB-3asmA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 5 ILE A 201
PHE A 204
ARG A 182
THR A 155
 None
 1.27A 5z84N-3asmA:
undetectable
5z84W-3asmA:
undetectable		 5z84N-3asmA:
19.81
5z84W-3asmA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3asm RIBONUCLEASE HIII
(Geobacillus
stearothermophil
us) 		4 / 9 LEU A 187
VAL A 115
SER A 237
ASP A 116
 None
 0.94A 6c2mD-3asmA:
undetectable		 6c2mD-3asmA:
12.34