SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3asp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 LEU A 256
TYR A 431
PRO A 423
VAL A 531
 None
 1.07A 1fduB-3aspA:
undetectable		 1fduB-3aspA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		4 / 5 ALA A 444
ASN A 440
ILE A 398
ASP A 397
 None
 1.14A 1yc2D-3aspA:
undetectable		 1yc2D-3aspA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		4 / 8 LEU A 490
ARG A 270
PRO A 423
VAL A 420
 None
 1.17A 2qd2A-3aspA:
undetectable		 2qd2A-3aspA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		3 / 3 MET A 333
CYH A 329
PRO A 324
 None
 1.33A 3h52C-3aspA:
undetectable		 3h52C-3aspA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		4 / 6 PHE A 360
PHE A 323
THR A 355
VAL A 353
 None
 1.27A 3lb3A-3aspA:
undetectable		 3lb3A-3aspA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		4 / 6 PHE A 360
PHE A 323
THR A 355
VAL A 353
 None
 1.30A 3lb3B-3aspA:
undetectable		 3lb3B-3aspA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		5 / 11 GLY A 293
ALA A 319
VAL A 291
PHE A 369
ILE A 295
 None
 1.45A 4j4vD-3aspA:
undetectable
4j4vE-3aspA:
undetectable		 4j4vD-3aspA:
21.96
4j4vE-3aspA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		4 / 7 LEU A 490
ARG A 270
PRO A 423
VAL A 420
 None
 1.10A 4klrA-3aspA:
undetectable		 4klrA-3aspA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_C_6ZPC902_1
(GLUTAMATE RECEPTOR 2)		 3asp CAPSID PROTEIN
(Norwalk
virus) 		4 / 7 PRO A 404
TYR A 406
PHE A 326
SER A 245
 None
 1.13A 5l1fC-3aspA:
undetectable		 5l1fC-3aspA:
16.25