SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3atb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3atb POTASSIUM
INWARDLY-RECTIFYING
CHANNEL, SUBFAMILY
J, MEMBER 6
(Mus
musculus) 		4 / 8 LEU A 299
SER A 295
LEU A 243
ILE A 213
 None
 0.80A 3ln1A-3atbA:
undetectable		 3ln1A-3atbA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3atb POTASSIUM
INWARDLY-RECTIFYING
CHANNEL, SUBFAMILY
J, MEMBER 6
(Mus
musculus) 		4 / 7 LEU A 299
SER A 295
LEU A 243
ILE A 213
 None
 0.81A 3ln1B-3atbA:
undetectable		 3ln1B-3atbA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3atb POTASSIUM
INWARDLY-RECTIFYING
CHANNEL, SUBFAMILY
J, MEMBER 6
(Mus
musculus) 		3 / 3 LYS A 202
ARG A  73
VAL A  72
 None
 0.91A 4x3uA-3atbA:
undetectable
4x3uB-3atbA:
undetectable		 4x3uA-3atbA:
18.36
4x3uB-3atbA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 3atb POTASSIUM
INWARDLY-RECTIFYING
CHANNEL, SUBFAMILY
J, MEMBER 6
(Mus
musculus) 		5 / 12 VAL A 351
ASP A  62
ASN A  71
GLU A 315
GLU A 203
 None
 1.44A 6gnfC-3atbA:
undetectable		 6gnfC-3atbA:
17.52