SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3atg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		3 / 3 ASN A  35
ALA A 211
ASN A 209
 None
None
GOL  A 262 ( 4.7A)
 0.83A 1n4fA-3atgA:
undetectable		 1n4fA-3atgA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		5 / 10 ARG A  72
GLY A 106
THR A  75
GLU A  27
SER A 117
 PO4  A 258 (-3.7A)
None
None
None
None
 1.50A 1z35A-3atgA:
undetectable		 1z35A-3atgA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		4 / 6 ASN A  47
SER A  48
ALA A  71
HIS A  26
 None
None
None
GOL  A 263 (-4.0A)
 1.32A 3aruA-3atgA:
undetectable		 3aruA-3atgA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		4 / 4 VAL A 232
PHE A 164
PHE A 160
VAL A 133
 None
 1.30A 3rv5C-3atgA:
undetectable
3rv5D-3atgA:
undetectable		 3rv5C-3atgA:
17.77
3rv5D-3atgA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		3 / 3 ASP A 233
GLY A  54
ASP A  51
 CA  A 301 (-3.4A)
CA  A 301 (-3.7A)
None
 0.63A 4xdtA-3atgA:
undetectable		 4xdtA-3atgA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		4 / 8 ILE A  58
LYS A 231
VAL A 210
GLN A  91
 None
 1.14A 5dqyA-3atgA:
undetectable		 5dqyA-3atgA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		4 / 6 ARG A  85
GLY A 182
THR A 166
GLU A  87
 None
 1.10A 5ny7A-3atgA:
undetectable		 5ny7A-3atgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3atg GLUCANASE
(Cellulosimicrobi
um
cellulans) 		4 / 7 GLU A  63
ALA A  30
GLY A  29
TYR A  41
 None
 1.07A 5uxdA-3atgA:
undetectable		 5uxdA-3atgA:
20.81