SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3att'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 PHE A 212
TYR A  93
PRO A  91
 None
 1.05A 1mcnA-3attA:
undetectable
1mcnB-3attA:
undetectable
1mcnP-3attA:
undetectable		 1mcnA-3attA:
22.56
1mcnB-3attA:
22.56
1mcnP-3attA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 338
VAL A 340
TRP A 209
 None
 0.81A 1nt5A-3attA:
undetectable		 1nt5A-3attA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ALA A 338
VAL A 340
TRP A 209
 None
 0.81A 1nt5B-3attA:
undetectable		 1nt5B-3attA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 250
GLN A 316
LEU A 323
LEU A 173
ARG A 312
 None
 1.34A 2ceoB-3attA:
undetectable		 2ceoB-3attA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_A_TP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A 244
LEU A 326
GLU A 277
ALA A 250
TYR A 315
 None
 1.24A 3apvA-3attA:
undetectable		 3apvA-3attA:
20.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ATT_A_ACTA1209_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 ASP A 249
ARG A 251
ASP A 267
GLU A 269
 ACT  A1209 (-3.3A)
ATP  A 510 ( 4.9A)
MG  A   1 (-2.1A)
MG  A   1 ( 3.0A)
 0.03A 3attA-3attA:
59.2		 3attA-3attA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 GLU A 277
THR A 198
ALA A 238
ALA A 239
 None
 1.00A 3ax9B-3attA:
undetectable		 3ax9B-3attA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 VAL A 113
VAL A 116
TRP A 268
 None
 0.86A 3l8lA-3attA:
undetectable
3l8lB-3attA:
undetectable		 3l8lA-3attA:
9.03
3l8lB-3attA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 GLU A 277
THR A 198
ALA A 238
ALA A 239
 None
 1.12A 3ns1C-3attA:
undetectable		 3ns1C-3attA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 PHE A 149
ASN A 152
PHE A 154
PRO A 303
GLN A 291
 None
 1.43A 4ac0A-3attA:
3.4		 4ac0A-3attA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3att PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 ASN A 152
ALA A 155
GLY A 150
THR A 148
 None
 1.13A 4bboC-3attA:
undetectable		 4bboC-3attA:
15.06