SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3au0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		4 / 4 SER A 425
LEU A 431
TYR A 468
GLY A 491
 None
 1.35A 1liiA-3au0A:
undetectable		 1liiA-3au0A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		4 / 6 SER A 276
ASN A 278
LEU A 301
ASP A 299
 None
 1.33A 1mxdA-3au0A:
undetectable		 1mxdA-3au0A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		4 / 6 SER A 337
SER A 443
ARG A 331
GLU A 444
 None
 1.38A 2c8aC-3au0A:
undetectable		 2c8aC-3au0A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		3 / 3 TYR A 359
ASP A 270
ASP A 272
 None
 0.88A 3ou6B-3au0A:
undetectable		 3ou6B-3au0A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		4 / 5 PHE A 309
ILE A 285
PHE A 307
PHE A 257
 None
 0.97A 3owxB-3au0A:
undetectable		 3owxB-3au0A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		5 / 12 GLY A 404
GLY A 479
ASP A 480
GLU A 507
ASN A 514
 None
 0.93A 3t7sA-3au0A:
undetectable		 3t7sA-3au0A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		5 / 12 GLY A 404
GLY A 479
ASP A 480
GLU A 507
ASN A 514
 None
 0.96A 3t7sB-3au0A:
undetectable		 3t7sB-3au0A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		5 / 12 GLY A 404
GLY A 479
ASP A 480
GLU A 507
ASN A 514
 None
 0.97A 3t7sD-3au0A:
undetectable		 3t7sD-3au0A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		5 / 11 THR A 439
VAL A 436
SER A 445
LEU A 488
VAL A 394
 None
 1.40A 3tbgA-3au0A:
undetectable		 3tbgA-3au0A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		4 / 8 ASN A 388
GLN A 387
GLY A 386
SER A 385
 None
 0.73A 4f93B-3au0A:
5.4		 4f93B-3au0A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		4 / 7 SER A 375
GLN A 377
TYR A 446
ASP A 232
 None
 1.11A 4hxyB-3au0A:
undetectable		 4hxyB-3au0A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 3au0 CLUMPING FACTOR B
(Staphylococcus
aureus) 		4 / 8 ALA A 334
THR A 393
VAL A 486
PHE A 395
 None
 1.04A 4ltwA-3au0A:
undetectable		 4ltwA-3au0A:
20.29