SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 THR A 266
PRO A 269
THR A 268
 None
 0.87A 1a7yB-3aupA:
undetectable		 1a7yB-3aupA:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 LEU A  12
LEU A  27
ALA A  25
ILE A 264
THR A 266
 None
 0.91A 1crbA-3aupA:
undetectable		 1crbA-3aupA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 THR A 266
PRO A 269
THR A 268
 None
 0.84A 1dscC-3aupA:
undetectable		 1dscC-3aupA:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 8 LEU A 168
PRO A 152
VAL A  38
GLY A 157
 None
 0.97A 1hrkA-3aupA:
undetectable		 1hrkA-3aupA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 8 LEU A 168
PRO A 152
VAL A  38
GLY A 157
 None
 0.98A 1hrkB-3aupA:
undetectable		 1hrkB-3aupA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 ASN A   8
GLY A 199
GLN A 181
ARG A 377
LEU A   9
 None
 1.28A 1m2zA-3aupA:
undetectable		 1m2zA-3aupA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 ASN A   8
GLY A 199
GLN A 181
ARG A 377
LEU A   9
 None
 1.29A 1m2zD-3aupA:
undetectable		 1m2zD-3aupA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 6 ASN A  16
ASP A  17
GLY A  18
THR A  20
 None
 0.79A 1n4fA-3aupA:
undetectable		 1n4fA-3aupA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 THR A 266
PRO A 269
THR A 268
 None
 0.86A 1ovfB-3aupA:
undetectable		 1ovfB-3aupA:
4.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 11 GLY A 362
SER A 265
ASP A  17
ASN A  16
HIS A  23
 None
 1.23A 2hmaA-3aupA:
undetectable		 2hmaA-3aupA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 8 LEU A 168
PRO A 152
VAL A  38
GLY A 157
 None
 0.92A 2po5A-3aupA:
undetectable		 2po5A-3aupA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 8 LEU A 168
PRO A 152
VAL A  38
GLY A 157
 None
 0.93A 2po5B-3aupA:
undetectable		 2po5B-3aupA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 GLY A 162
GLY A 160
ASP A  41
LEU A 168
LEU A 375
 None
 1.18A 2zw9B-3aupA:
undetectable		 2zw9B-3aupA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 6 HIS A  46
PHE A 139
LEU A  96
LEU A 111
 None
 0.94A 3bgdA-3aupA:
undetectable		 3bgdA-3aupA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 THR A 262
LEU A 361
VAL A 348
GLY A 347
LEU A 318
 None
 1.00A 3ijdA-3aupA:
undetectable		 3ijdA-3aupA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 8 ASP A 396
ALA A 395
SER A 192
TYR A 189
 None
 0.95A 3rodA-3aupA:
undetectable		 3rodA-3aupA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD2_1
(CYTOCHROME P450 2D6)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 9 LEU A 318
VAL A 234
LEU A 273
ILE A 359
PHE A 281
 None
 1.11A 3tbgD-3aupA:
undetectable		 3tbgD-3aupA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 THR A 225
ASN A 231
GLU A 229
 None
 0.43A 3v4tA-3aupA:
undetectable
3v4tC-3aupA:
undetectable		 3v4tA-3aupA:
22.55
3v4tC-3aupA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 7 ILE A 213
LEU A 387
LYS A 193
GLY A 194
 None
 1.04A 4hajA-3aupA:
undetectable		 4hajA-3aupA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 8 MET A 263
GLU A 229
THR A 360
VAL A 272
 None
 0.97A 4ik6B-3aupA:
undetectable		 4ik6B-3aupA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 SER A 167
ALA A 159
VAL A 158
 None
 0.50A 4o2bA-3aupA:
undetectable		 4o2bA-3aupA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 SER A 167
ALA A 159
VAL A 158
 None
 0.61A 4o2bC-3aupA:
undetectable		 4o2bC-3aupA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 LEU A 273
VAL A 348
ILE A 330
LEU A 335
LEU A 366
 None
 1.06A 4y0qA-3aupA:
undetectable		 4y0qA-3aupA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 ILE A 118
ALA A 120
ALA A 403
LEU A 131
PHE A 198
 None
 1.39A 4zo1X-3aupA:
undetectable		 4zo1X-3aupA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 VAL A 327
THR A 384
ARG A 329
 None
 0.74A 5b2sB-3aupA:
undetectable		 5b2sB-3aupA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		3 / 3 VAL A 327
THR A 384
ARG A 329
 None
 0.69A 5b2tB-3aupA:
undetectable		 5b2tB-3aupA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 7 VAL A 316
LEU A 318
LEU A 335
LEU A 346
 None
 0.44A 5jq7A-3aupA:
undetectable		 5jq7A-3aupA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		5 / 12 PRO A 169
LEU A 161
SER A 174
PHE A 198
GLY A 199
 None
 1.11A 5l6eA-3aupA:
undetectable		 5l6eA-3aupA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3aup BASIC 7S GLOBULIN
(Glycine
max) 		4 / 5 ASN A 369
VAL A 348
LEU A 346
SER A 331
 None
 1.03A 6a7pA-3aupA:
undetectable		 6a7pA-3aupA:
19.80