SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3auv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		3 / 3 ALA A 240
VAL A 234
TRP A 167
 None
 0.76A 1c4dA-3auvA:
undetectable
1c4dB-3auvA:
undetectable		 1c4dA-3auvA:
7.69
1c4dB-3auvA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		3 / 3 TRP A 167
ALA A 240
VAL A 234
 None
 0.95A 1c4dA-3auvA:
undetectable
1c4dB-3auvA:
undetectable		 1c4dA-3auvA:
7.69
1c4dB-3auvA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		3 / 3 ALA A 240
VAL A 234
TRP A 167
 None
 0.75A 1c4dC-3auvA:
undetectable
1c4dD-3auvA:
undetectable		 1c4dC-3auvA:
7.69
1c4dD-3auvA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		3 / 3 TRP A 167
ALA A 240
VAL A 234
 None
 0.79A 1c4dC-3auvA:
undetectable
1c4dD-3auvA:
undetectable		 1c4dC-3auvA:
7.69
1c4dD-3auvA:
7.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		4 / 7 ASP A 196
VAL A 198
GLY A 184
ILE A 185
 None
 0.80A 1t7iB-3auvA:
undetectable		 1t7iB-3auvA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		3 / 3 ALA A 240
VAL A 234
TRP A 167
 None
 0.88A 1tkqB-3auvA:
undetectable		 1tkqB-3auvA:
3.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		3 / 3 PHE A  82
TYR A 103
LEU A  58
 None
 0.72A 3keeB-3auvA:
undetectable		 3keeB-3auvA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		4 / 8 TYR A 193
TRP A 181
TRP A 167
PHE A 235
 None
 1.37A 4tzcB-3auvA:
undetectable
4tzcD-3auvA:
undetectable		 4tzcB-3auvA:
18.42
4tzcD-3auvA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		4 / 8 THR A  85
SER A  74
THR A  83
SER A  76
 None
 1.01A 5l4eA-3auvA:
undetectable
5l4eB-3auvA:
undetectable
5l4eC-3auvA:
undetectable
5l4eD-3auvA:
undetectable
5l4eE-3auvA:
undetectable		 5l4eA-3auvA:
20.50
5l4eB-3auvA:
20.50
5l4eC-3auvA:
20.50
5l4eD-3auvA:
20.50
5l4eE-3auvA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3auv SC-DSFV DERIVED FROM
THE G6-FAB
(Homo
sapiens) 		4 / 5 GLY A  79
ASP A  39
ARG A  35
GLN A 100
 None
 1.43A 5zrfB-3auvA:
undetectable		 5zrfB-3auvA:
16.16