SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3av3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		4 / 8 THR A 180
VAL A 181
LEU A 182
ALA A  21
 None
 0.87A 1fiqC-3av3A:
undetectable		 1fiqC-3av3A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		5 / 12 PHE A   7
GLY A  88
GLY A  10
ILE A  93
VAL A  43
 None
 0.96A 2hmyB-3av3A:
5.0		 2hmyB-3av3A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		4 / 6 SER A   9
PHE A  57
ILE A  72
PHE A  68
 None
 1.21A 2qeiA-3av3A:
undetectable		 2qeiA-3av3A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		4 / 7 VAL A  35
LEU A  33
TYR A  89
ILE A  93
 None
 1.01A 3avpA-3av3A:
undetectable		 3avpA-3av3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		4 / 8 THR A 180
VAL A 181
LEU A 182
ALA A  21
 None
 0.86A 3ax7A-3av3A:
undetectable		 3ax7A-3av3A:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		4 / 5 SER A   9
ARG A  38
PRO A  39
VAL A  56
 None
 1.39A 3sufC-3av3A:
undetectable		 3sufC-3av3A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		4 / 7 THR A 180
VAL A 181
LEU A 182
ALA A  21
 None
 0.91A 3uniA-3av3A:
undetectable		 3uniA-3av3A:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MHT_D_SAMD328_0
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI)		 3av3 PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Geobacillus
kaustophilus) 		5 / 12 PHE A   7
GLY A  88
GLY A  10
ILE A  93
VAL A  43
 None
 1.09A 6mhtA-3av3A:
4.5		 6mhtA-3av3A:
17.52