SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aw5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 9 LEU A  81
ILE A  69
VAL A  77
PHE A 120
MET A  79
 None
 1.48A 1gx8A-3aw5A:
undetectable		 1gx8A-3aw5A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.57A 1oe1A-3aw5A:
16.7		 1oe1A-3aw5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.56A 1oe2A-3aw5A:
3.8		 1oe2A-3aw5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 391
CYH A 460
PRO A 392
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
None
CU  A 701 (-3.4A)
 1.28A 1oe2A-3aw5A:
3.8		 1oe2A-3aw5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.60A 1oe3A-3aw5A:
16.7		 1oe3A-3aw5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.19A 1v55C-3aw5A:
undetectable
1v55N-3aw5A:
undetectable
1v55P-3aw5A:
undetectable		 1v55C-3aw5A:
18.91
1v55N-3aw5A:
22.18
1v55P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.21A 2fqdA-3aw5A:
45.3		 2fqdA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.15A 2fqeA-3aw5A:
45.4		 2fqeA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.21A 2fqeA-3aw5A:
45.4		 2fqeA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.83A 2fqeA-3aw5A:
45.4		 2fqeA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 459
HIS A 394
HIS A 396
HIS A 134
 C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.3A)
 1.35A 2fqeA-3aw5A:
45.4		 2fqeA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.16A 2fqfA-3aw5A:
45.2		 2fqfA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.17A 2fqfA-3aw5A:
45.2		 2fqfA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.81A 2fqfA-3aw5A:
45.2		 2fqfA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.17A 2fqgA-3aw5A:
45.3		 2fqgA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.20A 2fqgA-3aw5A:
45.3		 2fqgA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.82A 2fqgA-3aw5A:
45.3		 2fqgA-3aw5A:
29.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKC_A_TRPA1520_0
(FLAVIN-DEPENDENT
TRYPTOPHAN
HALOGENASE PRNA)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 10 PRO A 187
ILE A 193
HIS A 465
TYR A 185
ASN A 462
 None
None
CU  A 701 (-3.2A)
None
CU  A 701 ( 4.9A)
 1.22A 2jkcA-3aw5A:
0.0		 2jkcA-3aw5A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 HIS A 134
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.56A 2ozrF-3aw5A:
undetectable		 2ozrF-3aw5A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 ASP A 241
THR A 288
PRO A 289
 None
 0.61A 2pynB-3aw5A:
undetectable		 2pynB-3aw5A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 ASP A 241
THR A 288
PRO A 289
 None
 0.58A 2q64B-3aw5A:
undetectable		 2q64B-3aw5A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 ASP A 241
THR A 288
PRO A 289
 None
 0.61A 2qakB-3aw5A:
undetectable		 2qakB-3aw5A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A 134
HIS A 132
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
 1.07A 2wkoA-3aw5A:
undetectable		 2wkoA-3aw5A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.54A 2xxgA-3aw5A:
9.3		 2xxgA-3aw5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.57A 2xxgC-3aw5A:
11.7		 2xxgC-3aw5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 391
CYH A 460
PRO A 392
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
None
CU  A 701 (-3.4A)
 1.23A 2xxgC-3aw5A:
11.7		 2xxgC-3aw5A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.12A 3ablA-3aw5A:
undetectable
3ablC-3aw5A:
undetectable
3ablP-3aw5A:
undetectable		 3ablA-3aw5A:
22.18
3ablC-3aw5A:
18.91
3ablP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.15A 3ablC-3aw5A:
undetectable
3ablN-3aw5A:
undetectable
3ablP-3aw5A:
undetectable		 3ablC-3aw5A:
18.91
3ablN-3aw5A:
22.18
3ablP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.16A 3abmA-3aw5A:
undetectable
3abmC-3aw5A:
undetectable
3abmP-3aw5A:
undetectable		 3abmA-3aw5A:
22.18
3abmC-3aw5A:
18.91
3abmP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.15A 3asnC-3aw5A:
undetectable
3asnN-3aw5A:
undetectable
3asnP-3aw5A:
undetectable		 3asnC-3aw5A:
18.91
3asnN-3aw5A:
22.18
3asnP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.16A 3asoA-3aw5A:
undetectable
3asoC-3aw5A:
undetectable
3asoP-3aw5A:
undetectable		 3asoA-3aw5A:
22.18
3asoC-3aw5A:
18.91
3asoP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.16A 3asoC-3aw5A:
undetectable
3asoN-3aw5A:
undetectable
3asoP-3aw5A:
undetectable		 3asoC-3aw5A:
18.91
3asoN-3aw5A:
22.18
3asoP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 12 HIS A 461
THR A 432
GLU A 466
THR A 139
HIS A 396
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 4.5A)
None
C2O  A 702 ( 3.3A)
 1.42A 3ce6D-3aw5A:
undetectable		 3ce6D-3aw5A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 12 HIS A 371
GLY A 137
GLY A 469
MET A 471
HIS A 105
 None
 1.38A 3f8wB-3aw5A:
undetectable		 3f8wB-3aw5A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 HIS A 459
HIS A 394
HIS A 396
 C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.77A 3mihA-3aw5A:
undetectable		 3mihA-3aw5A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 ILE A 435
VAL A 441
ARG A 405
 None
 0.71A 3p73A-3aw5A:
2.3		 3p73A-3aw5A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 HIS A 134
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.26A 3qpkA-3aw5A:
27.6		 3qpkA-3aw5A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.16A 3qpkA-3aw5A:
27.6		 3qpkA-3aw5A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.85A 3qpkA-3aw5A:
27.6		 3qpkA-3aw5A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 HIS A 134
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.26A 3qpkB-3aw5A:
27.7		 3qpkB-3aw5A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.16A 3qpkB-3aw5A:
27.7		 3qpkB-3aw5A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.83A 3qpkB-3aw5A:
27.7		 3qpkB-3aw5A:
26.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 12 LEU A  85
LEU A  81
GLY A 146
LEU A 148
GLN A 147
 None
 1.32A 3tbgC-3aw5A:
undetectable		 3tbgC-3aw5A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 ASP A 241
THR A 288
PRO A 289
 None
 0.51A 3tkgD-3aw5A:
undetectable		 3tkgD-3aw5A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.17A 3wg7A-3aw5A:
undetectable
3wg7C-3aw5A:
undetectable
3wg7P-3aw5A:
undetectable		 3wg7A-3aw5A:
22.18
3wg7C-3aw5A:
18.91
3wg7P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.14A 3wg7C-3aw5A:
undetectable
3wg7N-3aw5A:
undetectable
3wg7P-3aw5A:
undetectable		 3wg7C-3aw5A:
18.91
3wg7N-3aw5A:
22.18
3wg7P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.17A 3x2qA-3aw5A:
undetectable
3x2qC-3aw5A:
undetectable
3x2qP-3aw5A:
undetectable		 3x2qA-3aw5A:
22.18
3x2qC-3aw5A:
18.91
3x2qP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.16A 3x2qC-3aw5A:
undetectable
3x2qN-3aw5A:
undetectable
3x2qP-3aw5A:
undetectable		 3x2qC-3aw5A:
18.91
3x2qN-3aw5A:
22.18
3x2qP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 391
CYH A 460
HIS A 465
MET A 470
 CU  A 701 (-3.1A)
CU  A 701 (-2.1A)
CU  A 701 (-3.2A)
CU  A 701 (-3.4A)
 0.18A 4ef3A-3aw5A:
45.2		 4ef3A-3aw5A:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  94
HIS A 132
HIS A 394
HIS A 461
 C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
 0.22A 4ef3A-3aw5A:
45.2		 4ef3A-3aw5A:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 396
HIS A 459
HIS A  92
HIS A 134
 C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.66A 4ef3A-3aw5A:
45.2		 4ef3A-3aw5A:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A  92
HIS A 134
HIS A 394
HIS A 396
HIS A 459
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.17A 4ef3A-3aw5A:
45.2		 4ef3A-3aw5A:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 394
HIS A 461
HIS A  92
HIS A  94
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.67A 4ef3A-3aw5A:
45.2		 4ef3A-3aw5A:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.20A 4ef3A-3aw5A:
45.2		 4ef3A-3aw5A:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.84A 4ef3A-3aw5A:
45.2		 4ef3A-3aw5A:
29.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 GLY A 215
GLY A 216
TYR A 218
ASN A 167
 None
 0.81A 4fgkB-3aw5A:
undetectable		 4fgkB-3aw5A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 136
THR A 139
GLU A 466
HIS A  92
 None
None
C2O  A 702 ( 4.5A)
CU  A 703 ( 3.0A)
 1.35A 4hvcB-3aw5A:
undetectable		 4hvcB-3aw5A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_1
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 136
THR A 139
GLU A 466
HIS A 396
 None
None
C2O  A 702 ( 4.5A)
C2O  A 702 ( 3.3A)
 0.98A 4hvcB-3aw5A:
undetectable		 4hvcB-3aw5A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 ILE A 173
VAL A 206
VAL A 201
ARG A 229
 None
 1.35A 4m6tA-3aw5A:
undetectable		 4m6tA-3aw5A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 9 ASP A  97
VAL A 153
ALA A 126
GLY A  95
GLY A 253
 None
 1.25A 4mm5A-3aw5A:
undetectable		 4mm5A-3aw5A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.18A 5b1aA-3aw5A:
undetectable
5b1aC-3aw5A:
undetectable
5b1aP-3aw5A:
undetectable		 5b1aA-3aw5A:
22.18
5b1aC-3aw5A:
18.91
5b1aP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.19A 5b3sA-3aw5A:
undetectable
5b3sC-3aw5A:
undetectable
5b3sP-3aw5A:
undetectable		 5b3sA-3aw5A:
22.18
5b3sC-3aw5A:
18.91
5b3sP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 ASP A 426
VAL A 250
LEU A 255
 None
 0.60A 5e5jB-3aw5A:
undetectable		 5e5jB-3aw5A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 12 LEU A 463
PHE A 143
ILE A 173
GLY A 225
HIS A 396
 None
None
None
None
C2O  A 702 ( 3.3A)
 1.23A 5fsaB-3aw5A:
undetectable		 5fsaB-3aw5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.12A 5iy5C-3aw5A:
undetectable
5iy5N-3aw5A:
undetectable
5iy5P-3aw5A:
undetectable		 5iy5C-3aw5A:
18.92
5iy5N-3aw5A:
22.18
5iy5P-3aw5A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 VAL A 276
LEU A 278
LEU A 220
LEU A 222
 None
 0.59A 5jq7A-3aw5A:
undetectable		 5jq7A-3aw5A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A  92
HIS A 134
HIS A 394
HIS A 396
HIS A 459
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.12A 5mejA-3aw5A:
13.3		 5mejA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 394
HIS A 461
HIS A  92
HIS A  94
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.66A 5mejA-3aw5A:
13.3		 5mejA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A  92
HIS A  94
HIS A 132
HIS A 394
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
 0.20A 5mejA-3aw5A:
13.3		 5mejA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A 394
HIS A 396
HIS A 459
HIS A  92
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.64A 5mejA-3aw5A:
13.3		 5mejA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 6 HIS A 394
HIS A 461
HIS A  92
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.78A 5mejA-3aw5A:
13.3		 5mejA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.13A 5mejA-3aw5A:
13.3		 5mejA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mejA-3aw5A:
13.3		 5mejA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A  92
HIS A 134
HIS A 394
HIS A 396
HIS A 459
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.14A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 394
HIS A 461
HIS A  92
HIS A  94
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.64A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 459
HIS A 394
HIS A 134
HIS A 396
HIS A  92
 C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
 1.46A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A  92
HIS A  94
HIS A 132
HIS A 394
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
 0.19A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A 394
HIS A 396
HIS A 459
HIS A  92
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.65A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 6 HIS A 394
HIS A 461
HIS A  92
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.77A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.13A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mewA-3aw5A:
13.2		 5mewA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A  92
HIS A 134
HIS A 394
HIS A 396
HIS A 459
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.15A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 394
HIS A 461
HIS A  92
HIS A  94
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.65A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 459
HIS A 394
HIS A 134
HIS A 396
HIS A  92
 C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
 1.47A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A  92
HIS A  94
HIS A 132
HIS A 394
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
 0.19A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A 394
HIS A 396
HIS A 459
HIS A  92
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.65A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 6 HIS A 394
HIS A 461
HIS A  92
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.78A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.11A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mhuA-3aw5A:
13.3		 5mhuA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A  92
HIS A 134
HIS A 394
HIS A 396
HIS A 459
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.16A 5mhvA-3aw5A:
31.6		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 394
HIS A 461
HIS A  92
HIS A  94
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.64A 5mhvA-3aw5A:
31.6		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 5 HIS A 459
HIS A 394
HIS A 134
HIS A 396
HIS A  92
 C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
 1.47A 5mhvA-3aw5A:
31.6		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A  92
HIS A  94
HIS A 132
HIS A 394
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
 0.18A 5mhvA-3aw5A:
31.5		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 6 HIS A 394
HIS A 396
HIS A 459
HIS A  92
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.66A 5mhvA-3aw5A:
31.5		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 6 HIS A 394
HIS A 461
HIS A  92
HIS A 132
 CU  A 703 ( 3.0A)
C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.3A)
 0.77A 5mhvA-3aw5A:
31.5		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.10A 5mhvA-3aw5A:
31.5		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mhvA-3aw5A:
31.5		 5mhvA-3aw5A:
27.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.18A 5mhwA-3aw5A:
31.5		 5mhwA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mhwA-3aw5A:
31.5		 5mhwA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.18A 5mhwA-3aw5A:
31.5		 5mhwA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5mhwA-3aw5A:
31.5		 5mhwA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5mhwA-3aw5A:
31.5		 5mhwA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.10A 5mhwA-3aw5A:
31.5		 5mhwA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mhwA-3aw5A:
31.5		 5mhwA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.18A 5mhxA-3aw5A:
13.2		 5mhxA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mhxA-3aw5A:
13.2		 5mhxA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5mhxA-3aw5A:
13.2		 5mhxA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5mhxA-3aw5A:
13.2		 5mhxA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5mhxA-3aw5A:
13.2		 5mhxA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.09A 5mhxA-3aw5A:
13.2		 5mhxA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mhxA-3aw5A:
13.2		 5mhxA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.19A 5mhyA-3aw5A:
13.2		 5mhyA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mhyA-3aw5A:
13.2		 5mhyA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5mhyA-3aw5A:
13.2		 5mhyA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5mhyA-3aw5A:
13.2		 5mhyA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5mhyA-3aw5A:
13.2		 5mhyA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.09A 5mhyA-3aw5A:
13.2		 5mhyA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mhyA-3aw5A:
13.2		 5mhyA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.20A 5mhzA-3aw5A:
31.6		 5mhzA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mhzA-3aw5A:
31.6		 5mhzA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5mhzA-3aw5A:
31.5		 5mhzA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.73A 5mhzA-3aw5A:
31.5		 5mhzA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5mhzA-3aw5A:
31.5		 5mhzA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.09A 5mhzA-3aw5A:
31.5		 5mhzA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mhzA-3aw5A:
31.5		 5mhzA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.20A 5mi1A-3aw5A:
13.2		 5mi1A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mi1A-3aw5A:
13.2		 5mi1A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5mi1A-3aw5A:
13.2		 5mi1A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5mi1A-3aw5A:
13.2		 5mi1A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5mi1A-3aw5A:
13.2		 5mi1A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.09A 5mi1A-3aw5A:
13.2		 5mi1A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mi1A-3aw5A:
13.2		 5mi1A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.20A 5mi2A-3aw5A:
13.2		 5mi2A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mi2A-3aw5A:
13.2		 5mi2A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5mi2A-3aw5A:
13.2		 5mi2A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5mi2A-3aw5A:
13.2		 5mi2A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5mi2A-3aw5A:
13.2		 5mi2A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.09A 5mi2A-3aw5A:
13.2		 5mi2A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mi2A-3aw5A:
13.2		 5mi2A-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.21A 5miaA-3aw5A:
13.2		 5miaA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.67A 5miaA-3aw5A:
13.2		 5miaA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5miaA-3aw5A:
13.2		 5miaA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5miaA-3aw5A:
13.2		 5miaA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5miaA-3aw5A:
13.2		 5miaA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.09A 5miaA-3aw5A:
13.2		 5miaA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5miaA-3aw5A:
13.2		 5miaA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.21A 5mibA-3aw5A:
13.2		 5mibA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mibA-3aw5A:
13.2		 5mibA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5mibA-3aw5A:
13.2		 5mibA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5mibA-3aw5A:
13.2		 5mibA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5mibA-3aw5A:
13.2		 5mibA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.08A 5mibA-3aw5A:
13.2		 5mibA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mibA-3aw5A:
13.2		 5mibA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.21A 5micA-3aw5A:
13.1		 5micA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5micA-3aw5A:
13.1		 5micA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5micA-3aw5A:
13.1		 5micA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.73A 5micA-3aw5A:
13.1		 5micA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.88A 5micA-3aw5A:
13.1		 5micA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.08A 5micA-3aw5A:
13.1		 5micA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5micA-3aw5A:
13.1		 5micA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.21A 5midA-3aw5A:
10.2		 5midA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5midA-3aw5A:
10.2		 5midA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5midA-3aw5A:
13.2		 5midA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.72A 5midA-3aw5A:
13.2		 5midA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.88A 5midA-3aw5A:
13.2		 5midA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.08A 5midA-3aw5A:
10.2		 5midA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5midA-3aw5A:
10.2		 5midA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 134
HIS A 394
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.21A 5mieA-3aw5A:
10.5		 5mieA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 461
HIS A  92
HIS A  94
HIS A 132
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
 0.68A 5mieA-3aw5A:
10.5		 5mieA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.19A 5mieA-3aw5A:
10.5		 5mieA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.73A 5mieA-3aw5A:
10.5		 5mieA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.88A 5mieA-3aw5A:
10.5		 5mieA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.08A 5mieA-3aw5A:
10.5		 5mieA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5mieA-3aw5A:
10.5		 5mieA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 HIS A 134
HIS A 396
HIS A 459
 C2O  A 702 (-3.3A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
 0.19A 5migA-3aw5A:
13.1		 5migA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A  92
HIS A  94
HIS A 132
HIS A 461
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
C2O  A 702 (-3.3A)
C2O  A 702 (-3.5A)
 0.20A 5migA-3aw5A:
13.1		 5migA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 394
HIS A 396
HIS A 459
HIS A 134
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
C2O  A 702 (-3.4A)
C2O  A 702 (-3.3A)
 0.73A 5migA-3aw5A:
13.1		 5migA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 5 HIS A 461
HIS A 394
HIS A 459
HIS A 396
 C2O  A 702 (-3.5A)
CU  A 703 ( 3.0A)
C2O  A 702 (-3.4A)
C2O  A 702 ( 3.3A)
 0.87A 5migA-3aw5A:
13.1		 5migA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A  92
HIS A  94
HIS A 394
HIS A 396
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
 0.08A 5migA-3aw5A:
13.1		 5migA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 HIS A 394
HIS A 396
HIS A  92
HIS A  94
 CU  A 703 ( 3.0A)
C2O  A 702 ( 3.3A)
CU  A 703 ( 3.0A)
C2O  A 702 ( 3.2A)
 0.79A 5migA-3aw5A:
13.1		 5migA-3aw5A:
26.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.16A 5w97A-3aw5A:
undetectable
5w97C-3aw5A:
undetectable
5w97c-3aw5A:
undetectable		 5w97A-3aw5A:
22.18
5w97C-3aw5A:
18.91
5w97c-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.19A 5w97C-3aw5A:
undetectable
5w97a-3aw5A:
undetectable
5w97c-3aw5A:
undetectable		 5w97C-3aw5A:
18.91
5w97a-3aw5A:
22.18
5w97c-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.17A 5wauC-3aw5A:
undetectable
5waua-3aw5A:
undetectable
5wauc-3aw5A:
undetectable		 5wauC-3aw5A:
18.91
5waua-3aw5A:
22.18
5wauc-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.15A 5x19A-3aw5A:
undetectable
5x19C-3aw5A:
undetectable
5x19P-3aw5A:
undetectable		 5x19A-3aw5A:
22.18
5x19C-3aw5A:
18.91
5x19P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.12A 5x1bA-3aw5A:
undetectable
5x1bC-3aw5A:
undetectable
5x1bP-3aw5A:
undetectable		 5x1bA-3aw5A:
22.18
5x1bC-3aw5A:
18.91
5x1bP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.14A 5x1fA-3aw5A:
undetectable
5x1fC-3aw5A:
undetectable
5x1fP-3aw5A:
undetectable		 5x1fA-3aw5A:
22.18
5x1fC-3aw5A:
18.91
5x1fP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.14A 5xdqA-3aw5A:
undetectable
5xdqC-3aw5A:
undetectable
5xdqP-3aw5A:
undetectable		 5xdqA-3aw5A:
22.18
5xdqC-3aw5A:
18.91
5xdqP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.13A 5xdqC-3aw5A:
undetectable
5xdqN-3aw5A:
undetectable
5xdqP-3aw5A:
undetectable		 5xdqC-3aw5A:
18.91
5xdqN-3aw5A:
22.18
5xdqP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.14A 5xdxC-3aw5A:
undetectable
5xdxN-3aw5A:
undetectable
5xdxP-3aw5A:
undetectable		 5xdxC-3aw5A:
18.91
5xdxN-3aw5A:
22.18
5xdxP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 THR A 139
GLU A 466
HIS A 396
 None
C2O  A 702 ( 4.5A)
C2O  A 702 ( 3.3A)
 0.88A 5xioA-3aw5A:
undetectable		 5xioA-3aw5A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 THR A 139
GLU A 466
HIS A 396
 None
C2O  A 702 ( 4.5A)
C2O  A 702 ( 3.3A)
 0.91A 5xiqB-3aw5A:
undetectable		 5xiqB-3aw5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		3 / 3 THR A 139
GLU A 466
HIS A 396
 None
C2O  A 702 ( 4.5A)
C2O  A 702 ( 3.3A)
 0.88A 5xiqD-3aw5A:
undetectable		 5xiqD-3aw5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		5 / 11 HIS A 459
HIS A 461
HIS A 134
VAL A  91
HIS A  94
 C2O  A 702 (-3.4A)
C2O  A 702 (-3.5A)
C2O  A 702 (-3.3A)
None
C2O  A 702 ( 3.2A)
 1.44A 5z0mA-3aw5A:
undetectable
5z0mB-3aw5A:
undetectable		 5z0mA-3aw5A:
13.55
5z0mB-3aw5A:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.18A 5z84A-3aw5A:
undetectable
5z84C-3aw5A:
undetectable
5z84P-3aw5A:
undetectable		 5z84A-3aw5A:
22.18
5z84C-3aw5A:
18.91
5z84P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.17A 5z84C-3aw5A:
undetectable
5z84N-3aw5A:
undetectable
5z84P-3aw5A:
undetectable		 5z84C-3aw5A:
18.91
5z84N-3aw5A:
22.18
5z84P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.19A 5z85A-3aw5A:
undetectable
5z85C-3aw5A:
undetectable
5z85P-3aw5A:
undetectable		 5z85A-3aw5A:
22.18
5z85C-3aw5A:
18.91
5z85P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 7 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.17A 5z85C-3aw5A:
undetectable
5z85N-3aw5A:
undetectable
5z85P-3aw5A:
undetectable		 5z85C-3aw5A:
18.91
5z85N-3aw5A:
22.18
5z85P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.17A 5z86A-3aw5A:
undetectable
5z86C-3aw5A:
undetectable
5z86P-3aw5A:
undetectable		 5z86A-3aw5A:
22.18
5z86C-3aw5A:
18.91
5z86P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.16A 5z86C-3aw5A:
undetectable
5z86N-3aw5A:
undetectable
5z86P-3aw5A:
undetectable		 5z86C-3aw5A:
18.91
5z86N-3aw5A:
22.18
5z86P-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.17A 5zcoA-3aw5A:
undetectable
5zcoC-3aw5A:
undetectable
5zcoP-3aw5A:
undetectable		 5zcoA-3aw5A:
22.18
5zcoC-3aw5A:
18.91
5zcoP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.17A 5zcoC-3aw5A:
undetectable
5zcoN-3aw5A:
undetectable
5zcoP-3aw5A:
undetectable		 5zcoC-3aw5A:
18.91
5zcoN-3aw5A:
22.18
5zcoP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.19A 5zcpA-3aw5A:
undetectable
5zcpC-3aw5A:
undetectable
5zcpP-3aw5A:
undetectable		 5zcpA-3aw5A:
22.18
5zcpC-3aw5A:
18.91
5zcpP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.18A 5zcpC-3aw5A:
undetectable
5zcpN-3aw5A:
undetectable
5zcpP-3aw5A:
undetectable		 5zcpC-3aw5A:
18.91
5zcpN-3aw5A:
22.18
5zcpP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 HIS A 461
THR A 139
HIS A  94
LEU A  85
 C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
None
 1.17A 5zcqA-3aw5A:
undetectable
5zcqC-3aw5A:
undetectable
5zcqP-3aw5A:
undetectable		 5zcqA-3aw5A:
22.18
5zcqC-3aw5A:
18.91
5zcqP-3aw5A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 ILE A 474
ASP A 103
HIS A 105
PRO A 106
 None
 0.62A 6ag0A-3aw5A:
2.2		 6ag0A-3aw5A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 ILE A 474
ASP A 103
HIS A 105
PRO A 106
 None
 0.63A 6ag0C-3aw5A:
2.3		 6ag0C-3aw5A:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 4 PRO A 258
LEU A 255
VAL A 274
ARG A 246
 None
 1.50A 6fgdA-3aw5A:
undetectable		 6fgdA-3aw5A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 6 MET A 471
GLY A 468
ALA A 140
LEU A 463
 None
 0.90A 6fosA-3aw5A:
undetectable		 6fosA-3aw5A:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3aw5 MULTICOPPER OXIDASE
(Pyrobaculum
aerophilum) 		4 / 8 LEU A  85
HIS A 461
THR A 139
HIS A  94
 None
C2O  A 702 (-3.5A)
None
C2O  A 702 ( 3.2A)
 1.16A 6nknC-3aw5A:
undetectable
6nknN-3aw5A:
undetectable
6nknP-3aw5A:
undetectable		 6nknC-3aw5A:
18.91
6nknN-3aw5A:
22.18
6nknP-3aw5A:
18.91