SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3aw8'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DVT_A_FLPA125_1 (TRANSTHYRETIN)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	4 / 8	LEU A  21 ALA A  17 LEU A  23 LEU A  28	None	0.98A	1dvtA-3aw8A: undetectable 1dvtB-3aw8A: undetectable	1dvtA-3aw8A: 15.26 1dvtB-3aw8A: 15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_B_SAMB200_0 (METHIONINE REPRESSOR)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 11	GLU A 172 GLY A 173 GLU A 253 LEU A 255 PRO A 110	AMP  A 370 (-4.4A) None None None None	1.36A	1mjqA-3aw8A: undetectable 1mjqB-3aw8A: undetectable	1mjqA-3aw8A: 14.16 1mjqB-3aw8A: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_A_1FLA2003_1 (SERUM ALBUMIN)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 9	LEU A 245 PHE A 256 LEU A 243 LEU A 237 ALA A  94	None	1.31A	2bxeA-3aw8A: undetectable	2bxeA-3aw8A: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXE_B_1FLB2003_1 (SERUM ALBUMIN)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 10	TYR A  65 LEU A 245 PHE A 256 LEU A 237 ALA A  94	None	1.14A	2bxeB-3aw8A: undetectable	2bxeB-3aw8A: 21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJF_B_ADNB2002_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	4 / 6	ARG A 140 GLU A  68 PRO A 261 ALA A  90	None	1.31A	2ejfB-3aw8A: undetectable	2ejfB-3aw8A: 23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_A_ADNA1501_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	4 / 7	ARG A 140 GLU A  68 PRO A 261 ALA A  90	None	1.34A	2ejgA-3aw8A: undetectable	2ejgA-3aw8A: 23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNI_A_MTKA501_1 (CYTOCHROME P450 2C8)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 12	SER A 211 SER A 266 SER A 182 VAL A 242 ALA A 185	None	1.29A	2nniA-3aw8A: undetectable	2nniA-3aw8A: 20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_A_CHDA3_0 (FERROCHELATASE)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	3 / 3	PRO A 261 LEU A 243 ARG A 187	None	0.84A	3aqiA-3aw8A: 2.2	3aqiA-3aw8A: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OGP_B_017B200_2 (FIV PROTEASE)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 9	GLY A  18 ALA A  17 ILE A 271 GLY A  11 ILE A   4	None	0.94A	3ogpB-3aw8A: undetectable	3ogpB-3aw8A: 13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SI7_D_ACTD4_0 (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	4 / 5	LEU A 287 LEU A  21 GLY A  22 GLY A  18	None	0.81A	3si7C-3aw8A: undetectable 3si7D-3aw8A: undetectable	3si7C-3aw8A: 22.59 3si7D-3aw8A: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KIR_B_RCXB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 12	VAL A 181 ALA A 301 GLY A 217 ALA A 218 LEU A 222	None	1.07A	5kirB-3aw8A: undetectable	5kirB-3aw8A: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TWJ_A_SAMA201_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 12	LEU A  14 ILE A   4 GLY A  40 LEU A 283 LEU A  23	None	1.01A	5twjA-3aw8A: undetectable	5twjA-3aw8A: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TWJ_B_SAMB201_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 10	LEU A  14 ILE A   4 GLY A  40 LEU A 283 LEU A  23	None	1.02A	5twjB-3aw8A: undetectable	5twjB-3aw8A: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TWJ_D_SAMD201_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE H)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	5 / 11	LEU A 305 GLY A 307 GLY A 333 LEU A 363 VAL A 360	None	0.79A	5twjD-3aw8A: undetectable	5twjD-3aw8A: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AZ3_1_PAR11801_1 (RRNA ALPHA RIBOSOMAL PROTEIN EL18)	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	4 / 4	ARG A 342 ARG A 343 GLY A 352 ARG A 355	None	1.50A	6az3P-3aw8A: 0.0	6az3P-3aw8A: 12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CE2_B_SVRB202_1 ()	3aw8	PHOSPHORIBOSYLAMINOI MIDAZOLE CARBOXYLASE, ATPASE SUBUNIT (Thermus thermophilus)	4 / 8	LEU A  14 LEU A 289 GLY A 288 ARG A 189	None	0.92A	6ce2A-3aw8A: undetectable	6ce2A-3aw8A: 13.83