SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ax1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 3ax1 SERRATE RNA EFFECTOR
MOLECULE
(Arabidopsis
thaliana) 		4 / 8 ASP A 452
TYR A 419
ARG A 434
THR A 341
 None
 1.35A 1ceaA-3ax1A:
undetectable
1ceaB-3ax1A:
undetectable		 1ceaA-3ax1A:
12.43
1ceaB-3ax1A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3ax1 SERRATE RNA EFFECTOR
MOLECULE
(Arabidopsis
thaliana) 		4 / 5 VAL A 363
ASN A 362
VAL A 386
ILE A 388
 None
 1.01A 1z2bC-3ax1A:
undetectable		 1z2bC-3ax1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3ax1 SERRATE RNA EFFECTOR
MOLECULE
(Arabidopsis
thaliana) 		4 / 7 VAL A 467
MET A 468
ALA A 470
TYR A 539
 None
 1.07A 4lb2A-3ax1A:
undetectable		 4lb2A-3ax1A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 3ax1 SERRATE RNA EFFECTOR
MOLECULE
(Arabidopsis
thaliana) 		3 / 3 ARG A 458
GLN A 462
GLU A 356
 None
 0.91A 4tvtA-3ax1A:
undetectable		 4tvtA-3ax1A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 3ax1 SERRATE RNA EFFECTOR
MOLECULE
(Arabidopsis
thaliana) 		3 / 3 ASN A 289
LEU A 262
PHE A 270
 None
 0.81A 5dsgA-3ax1A:
undetectable		 5dsgA-3ax1A:
21.95