SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3axs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4Y_A_TPVA501_1 (PROTEIN (HIV-1 PROTEASE))	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	5 / 10	LEU A 43 ASP A 132 GLY A 64 ILE A 68 VAL A 56	None SFG A 501 (-3.7A) None None None	1.01A	1d4yA-3axsA: undetectable	1d4yA-3axsA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K4T_D_TTCD990_1 (DNA TOPOISOMERASE I)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 304 ARG A 66 ASP A 132 THR A 159	None SFG A 501 (-4.3A) SFG A 501 (-3.7A) None	1.39A	1k4tA-3axsA: 0.1	1k4tA-3axsA: 21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT2_A_SAMA301_0 (FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	5 / 12	ALA A 62 SER A 63 SER A 86 ALA A 114 ASP A 132	SFG A 501 (-3.4A) SFG A 501 ( 4.4A) SFG A 501 ( 4.7A) SFG A 501 (-3.6A) SFG A 501 (-3.7A)	0.75A	1nt2A-3axsA: 13.7	1nt2A-3axsA: 18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T7I_A_017A200_2 (POL POLYPROTEIN)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 7	ALA A 162 GLY A 190 ILE A 193 THR A 136	SO4 A 503 (-3.5A) None None None	0.68A	1t7iB-3axsA: undetectable	1t7iB-3axsA: 16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T7J_A_478A200_2 (POL POLYPROTEIN)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 7	ALA A 162 GLY A 190 ILE A 193 THR A 136	SO4 A 503 (-3.5A) None None None	0.74A	1t7jB-3axsA: undetectable	1t7jB-3axsA: 16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_2 (RETINOIC ACID RECEPTOR, BETA)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	LEU A 194 PHE A 221 ARG A 182	None	0.89A	1xdkB-3axsA: undetectable	1xdkB-3axsA: 21.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EJT_A_SAMA501_0 (N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	5 / 12	ASP A 58 ILE A 68 ASN A 83 ILE A 85 ALA A 114	SFG A 501 ( 4.6A) None SFG A 501 ( 4.7A) SFG A 501 (-3.7A) SFG A 501 (-3.6A)	1.18A	2ejtA-3axsA: 44.3	2ejtA-3axsA: 38.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2EJT_A_SAMA501_0 (N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	11 / 12	ASP A 58 LEU A 60 ALA A 62 ILE A 65 ARG A 66 ASN A 83 ILE A 85 SER A 86 ALA A 114 ASP A 132 PHE A 140	SFG A 501 ( 4.6A) SFG A 501 (-3.7A) SFG A 501 (-3.4A) None SFG A 501 (-4.3A) SFG A 501 ( 4.7A) SFG A 501 (-3.7A) SFG A 501 ( 4.7A) SFG A 501 (-3.6A) SFG A 501 (-3.7A) None	0.50A	2ejtA-3axsA: 44.3	2ejtA-3axsA: 38.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NMZ_B_ROCB401_2 (PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ARG A 192 VAL A 358 THR A 355	None	0.73A	2nmzA-3axsA: undetectable	2nmzA-3axsA: 15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NNK_A_ROCA401_2 (PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ARG A 192 VAL A 358 THR A 355	None	0.75A	2nnkA-3axsA: undetectable	2nnkA-3axsA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4P_A_TPVA300_1 (PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	5 / 11	LEU A 43 ASP A 132 GLY A 64 ILE A 68 VAL A 56	None SFG A 501 (-3.7A) None None None	1.06A	2o4pA-3axsA: undetectable	2o4pA-3axsA: 16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q9R_A_BEZA203_0 (PROTEIN OF UNKNOWN FUNCTION)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	LEU A 72 GLY A 7 ILE A 65 ILE A 68	None	0.77A	2q9rA-3axsA: undetectable	2q9rA-3axsA: 17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WM3_A_NFLA1301_1 (NMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 6	LEU A 146 ARG A 229 LEU A 201 ASP A 206	None	1.06A	2wm3A-3axsA: 2.1	2wm3A-3axsA: 20.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AXT_A_SAMA397_0 (PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	12 / 12	ARG A 36 LEU A 60 ALA A 62 ILE A 65 ARG A 66 ASP A 84 ILE A 85 SER A 86 GLU A 113 ALA A 114 ASP A 132 PHE A 134	SFG A 501 (-4.2A) SFG A 501 (-3.7A) SFG A 501 (-3.4A) None SFG A 501 (-4.3A) SFG A 501 (-2.8A) SFG A 501 (-3.7A) SFG A 501 ( 4.7A) SFG A 501 (-4.0A) SFG A 501 (-3.6A) SFG A 501 (-3.7A) SFG A 501 (-3.3A)	0.20A	3axtA-3axsA: 66.8	3axtA-3axsA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3AXT_A_SAMA397_0 (PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	5 / 12	ILE A 68 ASP A 84 ILE A 85 GLU A 113 ALA A 114	None SFG A 501 (-2.8A) SFG A 501 (-3.7A) SFG A 501 (-4.0A) SFG A 501 (-3.6A)	1.04A	3axtA-3axsA: 66.8	3axtA-3axsA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_B_ROCB201_2 (HIV-1 PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ARG A 192 VAL A 358 THR A 355	None	0.82A	3k4vA-3axsA: undetectable	3k4vA-3axsA: 14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K4V_D_ROCD201_4 (HIV-1 PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ARG A 192 VAL A 358 THR A 355	None	0.84A	3k4vD-3axsA: undetectable	3k4vD-3axsA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_C_ACTC800_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ASP A 130 ARG A 36 ALA A 39	None SFG A 501 (-4.2A) None	0.67A	3mbgC-3axsA: undetectable	3mbgC-3axsA: 12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NDU_D_ROCD100_3 (PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ARG A 192 VAL A 358 THR A 355	None	0.84A	3nduD-3axsA: undetectable	3nduD-3axsA: 14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWR_A_ROCA401_2 (PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ARG A 192 VAL A 358 THR A 355	None	0.73A	3pwrA-3axsA: undetectable	3pwrA-3axsA: 15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SMT_A_ACTA1001_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD3)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	LEU A 41 GLY A 42 PHE A 292 ARG A 300	None	0.67A	3smtA-3axsA: undetectable	3smtA-3axsA: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TL9_A_ROCA401_2 (PROTEASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	ARG A 192 VAL A 358 THR A 355	None	0.78A	3tl9A-3axsA: undetectable	3tl9A-3axsA: 14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FOX_E_D16E301_1 (THYMIDYLATE SYNTHASE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	5 / 12	HIS A 187 SER A 216 ILE A 191 TRP A 280 PHE A 221	None	1.40A	4foxE-3axsA: undetectable	4foxE-3axsA: 20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8Z_A_BBIA402_1 (NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	PHE A 213 PHE A 224 LEU A 194 PRO A 137	None	1.18A	4o8zA-3axsA: undetectable	4o8zA-3axsA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_C_29SC601_2 (ESTROGEN RECEPTOR)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 6	LEU A 38 ASP A 130 HIS A 217 PRO A 133	None	0.97A	4xi3C-3axsA: undetectable	4xi3C-3axsA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_A_ADNA501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.14A	5hm8A-3axsA: 2.8	5hm8A-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_B_ADNB501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.14A	5hm8B-3axsA: 2.8	5hm8B-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_C_ADNC501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.14A	5hm8C-3axsA: 2.5	5hm8C-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_D_ADND501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.14A	5hm8D-3axsA: 2.8	5hm8D-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_E_ADNE501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.14A	5hm8E-3axsA: 4.5	5hm8E-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_F_ADNF501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.14A	5hm8F-3axsA: 5.0	5hm8F-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_G_ADNG501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.21A	5hm8G-3axsA: 4.4	5hm8G-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HM8_H_ADNH501_2 (ADENOSYLHOMOCYSTEINA SE)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	4 / 5	GLU A 73 THR A 74 GLU A 296 LEU A 38	None	1.14A	5hm8H-3axsA: 4.9	5hm8H-3axsA: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N4T_B_BEZB306_0 (BETA-LACTAMASE VIM-2)	3axs	PROBABLE N(2),N(2)-DIMETHYLGU ANOSINE TRNA METHYLTRANSFERASE TRM1 (Aquifex aeolicus)	3 / 3	HIS A 110 ASN A 83 ALA A 57	SO4 A 506 (-3.8A) SFG A 501 ( 4.7A) None	0.78A	5n4tB-3axsA: 2.0	5n4tB-3axsA: 21.05

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D4Y_A_TPVA501_1","PROTEIN (HIV-1 PROTEASE)","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",5,"LEU A  43;ASP A 132;GLY A  64;ILE A  68;VAL A  56","None;SFG A 501 (-3.7A);None;None;None","1.01A","1d4yA-3axsA:undetectable","1d4yA-3axsA:14.93"],["1K4T_D_TTCD990_1","DNA TOPOISOMERASE I","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A 304;ARG A  66;ASP A 132;THR A 159","None;SFG A 501 (-4.3A);SFG A 501 (-3.7A);None","1.39A","1k4tA-3axsA:0.1","1k4tA-3axsA:21.56"],["1NT2_A_SAMA301_0","FIBRILLARIN-LIKE PRE-RRNA PROCESSING PROTEIN","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",5,"ALA A  62;SER A  63;SER A  86;ALA A 114;ASP A 132","SFG A 501 (-3.4A);SFG A 501 ( 4.4A);SFG A 501 ( 4.7A);SFG A 501 (-3.6A);SFG A 501 (-3.7A)","0.75A","1nt2A-3axsA:13.7","1nt2A-3axsA:18.69"],["1T7I_A_017A200_2","POL POLYPROTEIN;POL POLYPROTEIN","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"ALA A 162;GLY A 190;ILE A 193;THR A 136","SO4 A 503 (-3.5A);None;None;None","0.68A","1t7iB-3axsA:undetectable","1t7iB-3axsA:16.06"],["1T7J_A_478A200_2","POL POLYPROTEIN;POL POLYPROTEIN","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"ALA A 162;GLY A 190;ILE A 193;THR A 136","SO4 A 503 (-3.5A);None;None;None","0.74A","1t7jB-3axsA:undetectable","1t7jB-3axsA:16.06"],["1XDK_B_9CRB600_2","RETINOIC ACID RECEPTOR, BETA","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"LEU A 194;PHE A 221;ARG A 182","None","0.89A","1xdkB-3axsA:undetectable","1xdkB-3axsA:21.09"],["2EJT_A_SAMA501_0","N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",5,"ASP A  58;ILE A  68;ASN A  83;ILE A  85;ALA A 114","SFG A 501 ( 4.6A);None;SFG A 501 ( 4.7A);SFG A 501 (-3.7A);SFG A 501 (-3.6A)","1.18A","2ejtA-3axsA:44.3","2ejtA-3axsA:38.52"],["2EJT_A_SAMA501_0","N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",11,"ASP A  58;LEU A  60;ALA A  62;ILE A  65;ARG A  66;ASN A  83;ILE A  85;SER A  86;ALA A 114;ASP A 132;PHE A 140","SFG A 501 ( 4.6A);SFG A 501 (-3.7A);SFG A 501 (-3.4A);None;SFG A 501 (-4.3A);SFG A 501 ( 4.7A);SFG A 501 (-3.7A);SFG A 501 ( 4.7A);SFG A 501 (-3.6A);SFG A 501 (-3.7A);None","0.50A","2ejtA-3axsA:44.3","2ejtA-3axsA:38.52"],["2NMZ_B_ROCB401_2","PROTEASE;PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ARG A 192;VAL A 358;THR A 355","None","0.73A","2nmzA-3axsA:undetectable","2nmzA-3axsA:15.21"],["2NNK_A_ROCA401_2","PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ARG A 192;VAL A 358;THR A 355","None","0.75A","2nnkA-3axsA:undetectable","2nnkA-3axsA:14.93"],["2O4P_A_TPVA300_1","PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",5,"LEU A  43;ASP A 132;GLY A  64;ILE A  68;VAL A  56","None;SFG A 501 (-3.7A);None;None;None","1.06A","2o4pA-3axsA:undetectable","2o4pA-3axsA:16.06"],["2Q9R_A_BEZA203_0","PROTEIN OF UNKNOWN FUNCTION","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"LEU A  72;GLY A   7;ILE A  65;ILE A  68","None","0.77A","2q9rA-3axsA:undetectable","2q9rA-3axsA:17.09"],["2WM3_A_NFLA1301_1","NMRA-LIKE FAMILY DOMAIN CONTAINING PROTEIN 1","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"LEU A 146;ARG A 229;LEU A 201;ASP A 206","None","1.06A","2wm3A-3axsA:2.1","2wm3A-3axsA:20.50"],["3AXT_A_SAMA397_0","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",12,"ARG A  36;LEU A  60;ALA A  62;ILE A  65;ARG A  66;ASP A  84;ILE A  85;SER A  86;GLU A 113;ALA A 114;ASP A 132;PHE A 134","SFG A 501 (-4.2A);SFG A 501 (-3.7A);SFG A 501 (-3.4A);None;SFG A 501 (-4.3A);SFG A 501 (-2.8A);SFG A 501 (-3.7A);SFG A 501 ( 4.7A);SFG A 501 (-4.0A);SFG A 501 (-3.6A);SFG A 501 (-3.7A);SFG A 501 (-3.3A)","0.20A","3axtA-3axsA:66.8","3axtA-3axsA:100.00"],["3AXT_A_SAMA397_0","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",5,"ILE A  68;ASP A  84;ILE A  85;GLU A 113;ALA A 114","None;SFG A 501 (-2.8A);SFG A 501 (-3.7A);SFG A 501 (-4.0A);SFG A 501 (-3.6A)","1.04A","3axtA-3axsA:66.8","3axtA-3axsA:100.00"],["3K4V_B_ROCB201_2","HIV-1 PROTEASE;HIV-1 PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ARG A 192;VAL A 358;THR A 355","None","0.82A","3k4vA-3axsA:undetectable","3k4vA-3axsA:14.40"],["3K4V_D_ROCD201_4","HIV-1 PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ARG A 192;VAL A 358;THR A 355","None","0.84A","3k4vD-3axsA:undetectable","3k4vD-3axsA:14.93"],["3MBG_C_ACTC800_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ASP A 130;ARG A  36;ALA A  39","None;SFG A 501 (-4.2A);None","0.67A","3mbgC-3axsA:undetectable","3mbgC-3axsA:12.81"],["3NDU_D_ROCD100_3","PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ARG A 192;VAL A 358;THR A 355","None","0.84A","3nduD-3axsA:undetectable","3nduD-3axsA:14.40"],["3PWR_A_ROCA401_2","PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ARG A 192;VAL A 358;THR A 355","None","0.73A","3pwrA-3axsA:undetectable","3pwrA-3axsA:15.21"],["3SMT_A_ACTA1001_0","HISTONE-LYSINE N-METHYLTRANSFERASE SETD3","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"LEU A  41;GLY A  42;PHE A 292;ARG A 300","None","0.67A","3smtA-3axsA:undetectable","3smtA-3axsA:22.20"],["3TL9_A_ROCA401_2","PROTEASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"ARG A 192;VAL A 358;THR A 355","None","0.78A","3tl9A-3axsA:undetectable","3tl9A-3axsA:14.40"],["4FOX_E_D16E301_1","THYMIDYLATE SYNTHASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",5,"HIS A 187;SER A 216;ILE A 191;TRP A 280;PHE A 221","None","1.40A","4foxE-3axsA:undetectable","4foxE-3axsA:20.40"],["4O8Z_A_BBIA402_1","NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-3, MITOCHONDRIAL","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"PHE A 213;PHE A 224;LEU A 194;PRO A 137","None","1.18A","4o8zA-3axsA:undetectable","4o8zA-3axsA:20.59"],["4XI3_C_29SC601_2","ESTROGEN RECEPTOR","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"LEU A  38;ASP A 130;HIS A 217;PRO A 133","None","0.97A","4xi3C-3axsA:undetectable","4xi3C-3axsA:22.40"],["5HM8_A_ADNA501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.14A","5hm8A-3axsA:2.8","5hm8A-3axsA:20.82"],["5HM8_B_ADNB501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.14A","5hm8B-3axsA:2.8","5hm8B-3axsA:20.82"],["5HM8_C_ADNC501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.14A","5hm8C-3axsA:2.5","5hm8C-3axsA:20.82"],["5HM8_D_ADND501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.14A","5hm8D-3axsA:2.8","5hm8D-3axsA:20.82"],["5HM8_E_ADNE501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.14A","5hm8E-3axsA:4.5","5hm8E-3axsA:20.82"],["5HM8_F_ADNF501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.14A","5hm8F-3axsA:5.0","5hm8F-3axsA:20.82"],["5HM8_G_ADNG501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.21A","5hm8G-3axsA:4.4","5hm8G-3axsA:20.82"],["5HM8_H_ADNH501_2","ADENOSYLHOMOCYSTEINASE","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",4,"GLU A  73;THR A  74;GLU A 296;LEU A  38","None","1.14A","5hm8H-3axsA:4.9","5hm8H-3axsA:20.82"],["5N4T_B_BEZB306_0","BETA-LACTAMASE VIM-2","3axs","PROBABLE N(2),N(2)-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRM1","Aquifex aeolicus",3,"HIS A 110;ASN A  83;ALA A  57","SO4 A 506 (-3.8A);SFG A 501 ( 4.7A);None","0.78A","5n4tB-3axsA:2.0","5n4tB-3axsA:21.05"]]