SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3axy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 11 PHE C 178
ILE C 159
ALA C 160
LEU C 174
ALA C 175
 None
 1.31A 1jb0B-3axyC:
undetectable		 1jb0B-3axyC:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		5 / 11 LEU A 130
ALA A 101
TYR A  67
LEU A 155
GLN A 128
 None
 1.45A 1kt6A-3axyA:
undetectable		 1kt6A-3axyA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		5 / 10 THR A 146
LEU A  69
VAL A  70
VAL A  16
VAL A  20
 None
 1.36A 1o76A-3axyA:
undetectable		 1o76A-3axyA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		3 / 3 ARG C  58
ARG C  62
ILE C  90
 None
 0.82A 1uobA-3axyC:
undetectable		 1uobA-3axyC:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		4 / 5 LEU A  11
ASN A  41
VAL A 123
ALA A 161
 None
 0.95A 2cizA-3axyA:
undetectable		 2cizA-3axyA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		4 / 7 ASP A  73
ALA A  76
GLY A 118
ILE A 119
 None
 0.85A 2fxdB-3axyA:
undetectable		 2fxdB-3axyA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH8_A_VIBA1_1
(MAJOR PRION PROTEIN)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		4 / 6 MET C 125
HIS C 130
ASP C  99
TYR C 132
 None
 1.47A 2lh8A-3axyC:
undetectable		 2lh8A-3axyC:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 11 PHE C 178
ILE C 159
ALA C 160
LEU C 174
ALA C 175
 None
 1.30A 3pcqB-3axyC:
2.4		 3pcqB-3axyC:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 12 VAL C  48
ASN C  44
ILE C  97
TYR C 129
TYR C 122
 None
 1.46A 3q5pA-3axyC:
undetectable		 3q5pA-3axyC:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		4 / 5 TYR A  67
THR A  68
PHE A 127
LEU A 130
 None
 1.23A 3qelC-3axyA:
undetectable		 3qelC-3axyA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 11 ARG C  58
LEU C  94
LEU C 102
GLY C 127
ASP C 128
 None
 1.45A 3sfuC-3axyC:
undetectable		 3sfuC-3axyC:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		3 / 3 LYS A  46
PRO A  47
SER A  48
 None
 0.40A 4k50I-3axyA:
undetectable		 4k50I-3axyA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		4 / 6 ASP C 190
ASN C 194
ALA C 192
TYR C 183
 None
 1.21A 4mdaA-3axyC:
undetectable		 4mdaA-3axyC:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 12 ILE C  54
ILE C 185
ALA C 134
LEU C 133
LEU C  94
 None
 0.96A 4o1zA-3axyC:
undetectable		 4o1zA-3axyC:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		3 / 3 LYS A   5
ARG A  15
VAL A  16
 None
 1.05A 4x3uA-3axyA:
undetectable
4x3uB-3axyA:
undetectable		 4x3uA-3axyA:
15.79
4x3uB-3axyA:
15.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		4 / 5 PHE C 200
ILE C 204
MET C 222
GLN C 223
 None
 0.49A 5jm4A-3axyC:
32.2		 5jm4A-3axyC:
65.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M35_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		4 / 5 PHE C 200
THR C 219
MET C 222
GLN C 223
 None
 0.54A 5m35A-3axyC:
32.8		 5m35A-3axyC:
63.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3axy PROTEIN HEADING DATE
3A
(Oryza
sativa) 		3 / 3 ARG A  26
PHE A 124
LEU A  11
 None
 0.87A 5x1bC-3axyA:
undetectable		 5x1bC-3axyA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 12 ALA C 146
ALA C 145
ILE C  54
CYH C  98
LEU C 102
 None
 0.99A 6a5yD-3axyC:
undetectable		 6a5yD-3axyC:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 12 ALA C 146
ALA C 145
ILE C  54
CYH C  98
LEU C 102
 None
 0.97A 6a5zL-3axyC:
undetectable		 6a5zL-3axyC:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		5 / 12 GLY C 173
SER C 113
LEU C 109
VAL C 110
ASP C 128
 None
 1.22A 6bxmA-3axyC:
undetectable		 6bxmA-3axyC:
21.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)		 3axy 14-3-3-LIKE PROTEIN
GF14-C
(Oryza
sativa) 		4 / 5 SER C  47
VAL C  48
LYS C  51
ASN C  52
 None
 1.01A 6fi4A-3axyC:
30.6
6fi4B-3axyC:
undetectable		 6fi4A-3axyC:
61.34
6fi4B-3axyC:
7.14