SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ay2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 GLY A 143
ASP A  67
MET A 175
ILE A 142
LEU A  89
 None
None
ZN  A1001 (-3.5A)
None
None
 1.33A 1lhuA-3ay2A:
undetectable		 1lhuA-3ay2A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.39A 1oe1A-3ay2A:
4.4		 1oe1A-3ay2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 5 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.39A 1oe2A-3ay2A:
8.4		 1oe2A-3ay2A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.43A 1oe3A-3ay2A:
4.4		 1oe3A-3ay2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 8 LEU A 150
VAL A  63
VAL A  78
VAL A 136
 None
 1.02A 2bdmA-3ay2A:
undetectable		 2bdmA-3ay2A:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.46A 2fqdA-3ay2A:
3.2		 2fqdA-3ay2A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.44A 2fqeA-3ay2A:
3.4		 2fqeA-3ay2A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.44A 2fqfA-3ay2A:
3.3		 2fqfA-3ay2A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.49A 2fqgA-3ay2A:
3.3		 2fqgA-3ay2A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		3 / 3 HIS A 171
MET A 175
MET A 100
 ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
None
 1.42A 2vj1A-3ay2A:
undetectable		 2vj1A-3ay2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.39A 2xxgA-3ay2A:
3.3		 2xxgA-3ay2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 5 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.42A 2xxgC-3ay2A:
3.2		 2xxgC-3ay2A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		3 / 3 HIS A 171
HIS A 102
MET A 100
 ZN  A1001 (-3.2A)
ZN  A1001 (-3.0A)
None
 1.04A 3mihA-3ay2A:
undetectable		 3mihA-3ay2A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 HIS A 102
CYH A 166
HIS A 171
MET A 175
 ZN  A1001 (-3.0A)
ZN  A1001 (-2.3A)
ZN  A1001 (-3.2A)
ZN  A1001 (-3.5A)
 0.48A 4ef3A-3ay2A:
3.3		 4ef3A-3ay2A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 7 GLU A 110
ASP A 111
ALA A 109
TYR A 162
 None
 1.14A 4zz8A-3ay2A:
undetectable		 4zz8A-3ay2A:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 8 SER A  65
HIS A  91
GLN A  95
MET A 175
 None
None
None
ZN  A1001 (-3.5A)
 1.40A 5u6nA-3ay2A:
undetectable		 5u6nA-3ay2A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3ay2 LIPID MODIFIED
AZURIN PROTEIN
(Neisseria
gonorrhoeae) 		4 / 6 SER A  65
HIS A  91
GLN A  95
MET A 175
 None
None
None
ZN  A1001 (-3.5A)
 1.37A 5u6nB-3ay2A:
undetectable		 5u6nB-3ay2A:
15.99