SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ay8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 3ay8 GLUTATHIONE
S-TRANSFERASE
(Bombyx
mori) 		5 / 9 TYR A  74
TYR A  79
ILE A  27
ILE A  25
ILE A 158
 None
 1.38A 3p4wA-3ay8A:
undetectable		 3p4wA-3ay8A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 3ay8 GLUTATHIONE
S-TRANSFERASE
(Bombyx
mori) 		4 / 8 LEU A   6
ILE A  29
GLY A  26
ILE A  25
 None
None
GOL  A 217 ( 3.8A)
None
 0.84A 3wxoA-3ay8A:
undetectable		 3wxoA-3ay8A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 3ay8 GLUTATHIONE
S-TRANSFERASE
(Bombyx
mori) 		5 / 12 SER A 169
ILE A 114
ASP A 132
GLN A 128
ILE A 126
 None
 1.30A 4uroB-3ay8A:
undetectable		 4uroB-3ay8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 3ay8 GLUTATHIONE
S-TRANSFERASE
(Bombyx
mori) 		4 / 6 LEU A   6
ILE A  71
ALA A  72
ALA A  24
 None
 0.49A 4zf8A-3ay8A:
undetectable		 4zf8A-3ay8A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 3ay8 GLUTATHIONE
S-TRANSFERASE
(Bombyx
mori) 		5 / 10 TYR A  74
TYR A  79
ILE A  27
ILE A  25
ILE A 158
 None
 1.23A 5mvnD-3ay8A:
undetectable		 5mvnD-3ay8A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3ay8 GLUTATHIONE
S-TRANSFERASE
(Bombyx
mori) 		5 / 10 SER A  12
GLY A  13
ILE A  71
ALA A  18
LEU A  19
 None
 1.09A 5zjiA-3ay8A:
undetectable
5zjiJ-3ay8A:
undetectable		 5zjiA-3ay8A:
18.42
5zjiJ-3ay8A:
12.14