SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3azc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		5 / 12 TYR A  69
ILE A  99
ILE A  84
ALA A  54
THR A 156
 None
 1.23A 1jtxA-3azcA:
undetectable		 1jtxA-3azcA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		5 / 12 THR A 173
VAL A 140
PHE A 171
LEU A 104
TRP A 179
 None
 1.11A 1wsvA-3azcA:
undetectable		 1wsvA-3azcA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		5 / 12 THR A 173
VAL A 140
PHE A 171
LEU A 104
TRP A 179
 None
 1.15A 1wsvB-3azcA:
undetectable		 1wsvB-3azcA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		3 / 3 ARG A 172
VAL A 151
TRP A 179
 None
 1.26A 1zviA-3azcA:
undetectable		 1zviA-3azcA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		5 / 11 ASP A 134
GLU A  95
ILE A  92
TYR A 102
PHE A 124
 None
 1.36A 2dg3A-3azcA:
undetectable		 2dg3A-3azcA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		4 / 6 TYR A 133
TRP A 178
TRP A 179
THR A  89
 None
 1.45A 2x2iB-3azcA:
undetectable		 2x2iB-3azcA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		5 / 12 THR A  89
PHE A 163
ILE A  99
TYR A  69
THR A  94
 None
 1.41A 3elzC-3azcA:
undetectable		 3elzC-3azcA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA500_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		4 / 4 ALA A 144
HIS A 110
HIS A 129
PRO A 143
 None
FES  A 201 (-3.1A)
FES  A 201 (-3.1A)
FES  A 201 ( 4.7A)
 1.29A 3mbgA-3azcA:
undetectable		 3mbgA-3azcA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC900_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		4 / 4 ALA A 144
HIS A 110
HIS A 129
PRO A 143
 None
FES  A 201 (-3.1A)
FES  A 201 (-3.1A)
FES  A 201 ( 4.7A)
 1.28A 3mbgC-3azcA:
undetectable		 3mbgC-3azcA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		4 / 6 LYS A  65
ASP A  63
ASP A  58
LYS A  57
 None
 1.44A 3pocB-3azcA:
undetectable		 3pocB-3azcA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		5 / 10 ASP A 134
GLU A  95
ILE A  92
TYR A 102
PHE A 124
 None
 1.35A 4qt2A-3azcA:
undetectable		 4qt2A-3azcA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		5 / 10 ASP A 134
GLU A  95
ILE A  92
TYR A 102
PHE A 124
 None
 1.35A 4qt3A-3azcA:
undetectable		 4qt3A-3azcA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 3azc CYTOCHROME B6-F
COMPLEX IRON-SULFUR
SUBUNIT
(Thermosynechococ
cus
elongatus) 		3 / 3 ASP A  96
VAL A  93
LEU A  70
 None
 0.53A 5e5jB-3azcA:
undetectable		 5e5jB-3azcA:
22.39