SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3azq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_1
(ADENOSINE DEAMINASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 ALA A 315
GLY A 314
GLU A 285
HIS A 311
ASP A 330
None
SO4  A1006 ( 3.8A)
None
None
None
1.42A 1a4lD-3azqA:
undetectable
1a4lD-3azqA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.15A 1jffB-3azqA:
undetectable
1jffB-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 ALA A 308
VAL A 310
TRP A 338
None
0.92A 1jnoA-3azqA:
undetectable
1jnoA-3azqA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 ALA A 308
VAL A 310
TRP A 338
None
0.92A 1jnoB-3azqA:
undetectable
1jnoB-3azqA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 ALA A 308
VAL A 310
TRP A 338
None
0.91A 1magA-3azqA:
undetectable
1magA-3azqA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 ALA A 308
VAL A 310
TRP A 338
None
0.91A 1magB-3azqA:
undetectable
1magB-3azqA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.32A 1v8bA-3azqA:
3.2
1v8bA-3azqA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 GLU A 631
GLU A 638
LEU A 588
None
0.55A 1v8bA-3azqA:
3.2
1v8bA-3azqA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.31A 1v8bB-3azqA:
3.1
1v8bB-3azqA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.32A 1v8bC-3azqA:
undetectable
1v8bC-3azqA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.34A 1v8bD-3azqA:
2.6
1v8bD-3azqA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 VAL A 317
VAL A 309
TRP A 338
None
0.84A 1w5uA-3azqA:
undetectable
1w5uB-3azqA:
undetectable
1w5uA-3azqA:
2.05
1w5uB-3azqA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 10 ALA A 639
LEU A 658
LEU A 586
ALA A 616
LEU A 533
None
0.93A 2bxeA-3azqA:
undetectable
2bxeA-3azqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 11 ALA A 636
ALA A 639
LEU A 586
ALA A 616
LEU A 533
None
0.89A 2bxeB-3azqA:
undetectable
2bxeB-3azqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 11 ARG A 635
ALA A 636
ALA A 639
LEU A 586
ALA A 616
None
0.73A 2bxeB-3azqA:
undetectable
2bxeB-3azqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
6 / 10 ALA A 636
ALA A 639
LEU A 658
LEU A 586
ALA A 616
LEU A 533
None
1.01A 2bxgB-3azqA:
undetectable
2bxgB-3azqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 10 ARG A 635
ALA A 636
ALA A 639
LEU A 586
ALA A 616
None
0.80A 2bxgB-3azqA:
undetectable
2bxgB-3azqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 8 SER A 519
LEU A 537
PRO A 535
ASP A 483
None
0.95A 2ddwA-3azqA:
undetectable
2ddwA-3azqA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 8 GLY A 432
GLY A 433
ALA A 511
ALA A 512
HIS A 625
None
0.76A 2ha4A-3azqA:
7.3
2ha4A-3azqA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 8 GLY A 433
ALA A 511
ALA A 512
HIS A 625
None
0.48A 2ha4A-3azqA:
7.3
2ha4A-3azqA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 7 GLY A 432
GLY A 433
ALA A 511
ALA A 512
HIS A 625
None
0.76A 2ha4B-3azqA:
16.5
2ha4B-3azqA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.15A 2hxfB-3azqA:
undetectable
2hxfB-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.15A 2hxhB-3azqA:
undetectable
2hxhB-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 VAL A 309
TRP A 338
VAL A 317
None
0.85A 2izqC-3azqA:
undetectable
2izqD-3azqA:
undetectable
2izqC-3azqA:
2.05
2izqD-3azqA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.15A 2p4nB-3azqA:
2.1
2p4nB-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 GLY A  33
ASP A  34
SER A 345
None
0.69A 2qhfA-3azqA:
undetectable
2qhfA-3azqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.15A 2wbeB-3azqA:
undetectable
2wbeB-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 6 TYR A 569
TRP A 479
ARG A 572
THR A 576
None
1.42A 2x2iB-3azqA:
0.0
2x2iB-3azqA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 GLY A 463
TYR A 471
SER A 464
None
0.63A 2xatA-3azqA:
undetectable
2xatA-3azqA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 7 PRO A 251
SER A 254
ILE A 256
GLY A 305
None
0.95A 2y7kA-3azqA:
undetectable
2y7kA-3azqA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.38A 2zj0B-3azqA:
4.9
2zj0B-3azqA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.35A 3ce6A-3azqA:
2.1
3ce6A-3azqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.35A 3ce6B-3azqA:
3.6
3ce6B-3azqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 3ce6C-3azqA:
undetectable
3ce6C-3azqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.34A 3ce6D-3azqA:
undetectable
3ce6D-3azqA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.15A 3dcoB-3azqA:
2.1
3dcoB-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.13A 3edlB-3azqA:
2.1
3edlB-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 3g1uC-3azqA:
2.4
3g1uC-3azqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.30A 3g1uD-3azqA:
3.9
3g1uD-3azqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 3glqA-3azqA:
3.2
3glqA-3azqA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 484
LEU A 555
SER A 523
LEU A 539
GLY A 514
None
1.13A 3iz0B-3azqA:
2.1
3iz0B-3azqA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.30A 3n58A-3azqA:
4.5
3n58A-3azqA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.35A 3ondA-3azqA:
4.4
3ondA-3azqA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.35A 3ondB-3azqA:
3.0
3ondB-3azqA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 8 LEU A 558
TYR A 554
PHE A 557
TYR A 461
None
1.30A 3po7A-3azqA:
undetectable
3po7A-3azqA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 6 LEU A 306
PRO A 301
LEU A 267
LEU A 280
None
1.07A 3q1eA-3azqA:
undetectable
3q1eC-3azqA:
undetectable
3q1eA-3azqA:
11.18
3q1eC-3azqA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 8 LEU A 444
ALA A 447
SER A 451
SER A  12
TYR A 388
None
1.35A 3rodA-3azqA:
undetectable
3rodA-3azqA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_B_NCAB302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 9 LEU A 444
ALA A 447
SER A 451
SER A  12
TYR A 388
None
1.44A 3rodB-3azqA:
1.5
3rodB-3azqA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 6 ASP A 486
VAL A 482
ASP A 483
THR A 516
None
1.21A 3vqrA-3azqA:
undetectable
3vqrA-3azqA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 5 ASP A 486
VAL A 482
ASP A 483
THR A 516
None
1.21A 3vqrB-3azqA:
undetectable
3vqrB-3azqA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 10 LEU A 255
VAL A 257
LEU A 236
THR A 235
VAL A 270
None
0.99A 4e3hA-3azqA:
undetectable
4e3hA-3azqA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.31A 4lvcC-3azqA:
3.0
4lvcC-3azqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 ILE A 256
GLY A 319
LEU A 321
LEU A 267
LEU A 280
None
0.96A 4o1zA-3azqA:
undetectable
4o1zA-3azqA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 ALA A 511
GLY A 513
GLY A 514
ASP A 483
GLY A 626
None
0.96A 4obwB-3azqA:
2.1
4obwB-3azqA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB602_1
(SERUM ALBUMIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 9 ALA A 578
ALA A 607
LEU A 605
LEU A 575
SER A 519
None
1.12A 4or0B-3azqA:
undetectable
4or0B-3azqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 4pfjA-3azqA:
3.6
4pfjA-3azqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.29A 4pfjB-3azqA:
3.3
4pfjB-3azqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 GLN A 279
HIS A 268
ARG A 261
None
None
SO4  A1003 (-3.8A)
1.04A 4qyqA-3azqA:
undetectable
4qyqA-3azqA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 GLN A 279
HIS A 268
ARG A 261
None
None
SO4  A1003 (-3.8A)
1.04A 4qyqB-3azqA:
undetectable
4qyqB-3azqA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 8 HIS A 548
GLU A  76
ASP A 549
ARG A 188
None
None
None
SO4  A1001 (-3.9A)
1.01A 4uhxA-3azqA:
undetectable
4uhxA-3azqA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 8 HIS A 548
GLU A  76
ASP A 549
ARG A 188
None
None
None
SO4  A1001 (-3.9A)
1.01A 4uhxA-3azqA:
undetectable
4uhxA-3azqA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 5 LEU A 219
GLU A 248
LEU A 163
HIS A 187
None
1.29A 4xi3B-3azqA:
undetectable
4xi3B-3azqA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 6 TYR A 471
HIS A 405
GLY A 314
ARG A 437
None
None
SO4  A1006 ( 3.8A)
SO4  A1006 (-3.7A)
1.31A 4zbqA-3azqA:
undetectable
4zbqA-3azqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.31A 5axaA-3azqA:
5.0
5axaA-3azqA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 5axaC-3azqA:
3.2
5axaC-3azqA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
4 / 6 SER A  78
ARG A  48
GLY A  47
GLU A  45
None
1.10A 5btcA-3azqA:
undetectable
5btcC-3azqA:
undetectable
5btcD-3azqA:
2.7
5btcA-3azqA:
22.34
5btcC-3azqA:
22.34
5btcD-3azqA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8A-3azqA:
undetectable
5hm8A-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8B-3azqA:
undetectable
5hm8B-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8C-3azqA:
undetectable
5hm8C-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8D-3azqA:
3.0
5hm8D-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8E-3azqA:
undetectable
5hm8E-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8F-3azqA:
3.2
5hm8F-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8G-3azqA:
undetectable
5hm8G-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.36A 5hm8H-3azqA:
4.1
5hm8H-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A 144
ALA A  83
VAL A  95
GLY A  30
THR A 343
None
1.43A 5igpA-3azqA:
0.5
5igpA-3azqA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 435
ALA A 245
ALA A 258
LEU A 267
GLY A 289
None
1.49A 5jglA-3azqA:
undetectable
5jglA-3azqA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 GLU A 248
LEU A 195
ASP A 134
GLY A 192
ALA A 222
None
1.21A 5kc4E-3azqA:
undetectable
5kc4E-3azqA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.31A 5m5kA-3azqA:
4.3
5m5kA-3azqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.30A 5m5kC-3azqA:
2.7
5m5kC-3azqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.30A 5m66A-3azqA:
3.3
5m66A-3azqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.28A 5m66B-3azqA:
3.2
5m66B-3azqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.32A 5m66C-3azqA:
undetectable
5m66C-3azqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.30A 5m66D-3azqA:
2.6
5m66D-3azqA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 5utuF-3azqA:
undetectable
5utuF-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_1
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.32A 5utuH-3azqA:
undetectable
5utuH-3azqA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.28A 5v96A-3azqA:
undetectable
5v96A-3azqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.28A 5v96B-3azqA:
4.3
5v96B-3azqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.28A 5v96C-3azqA:
undetectable
5v96C-3azqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.27A 5v96D-3azqA:
undetectable
5v96D-3azqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
3 / 3 SER A 436
HIS A 431
TYR A 461
None
1.05A 5y2tA-3azqA:
undetectable
5y2tA-3azqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA502_0
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.27A 6exiA-3azqA:
2.7
6exiA-3azqA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.29A 6exiD-3azqA:
2.6
6exiD-3azqA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_1
(-)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.32A 6f3mD-3azqA:
undetectable
6f3mD-3azqA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_1
(-)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 6f3nA-3azqA:
4.4
6f3nA-3azqA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_1
(-)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.33A 6f3nB-3azqA:
4.5
6f3nB-3azqA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.32A 6f3nC-3azqA:
4.1
6f3nC-3azqA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_1
(-)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.32A 6f3nD-3azqA:
4.5
6f3nD-3azqA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 VAL A  95
LEU A  93
ALA A  83
GLY A  84
LEU A 168
None
0.81A 6f6iA-3azqA:
undetectable
6f6iB-3azqA:
undetectable
6f6iA-3azqA:
8.71
6f6iB-3azqA:
11.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_1
(-)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.34A 6gbnA-3azqA:
4.1
6gbnA-3azqA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_1
(-)
3azq AMINOPEPTIDASE
(Streptomyces
morookaense)
5 / 12 THR A 531
ASP A 445
LEU A 533
GLY A 509
PHE A 449
None
1.34A 6gbnD-3azqA:
3.9
6gbnD-3azqA:
22.54