SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 5 LEU A  86
VAL A  89
LEU A  93
GLN A  96
 None
 0.68A 1fbmE-3b02A:
undetectable		 1fbmE-3b02A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 8 TYR A  63
ARG A  13
TYR A  11
GLU A  32
 None
 1.25A 1nx9A-3b02A:
undetectable		 1nx9A-3b02A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 8 TYR A  63
ARG A  13
TYR A  11
GLU A  32
 None
 1.24A 1nx9B-3b02A:
undetectable		 1nx9B-3b02A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 8 TYR A  63
ARG A  13
TYR A  11
GLU A  32
 None
 1.24A 1nx9C-3b02A:
undetectable		 1nx9C-3b02A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 8 TYR A  63
ARG A  13
TYR A  11
GLU A  32
 None
 1.25A 1nx9D-3b02A:
undetectable		 1nx9D-3b02A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		3 / 3 GLU A  70
THR A  69
LEU A  23
 None
 0.67A 1v8bC-3b02A:
undetectable		 1v8bC-3b02A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 6 ARG A 165
ILE A 169
LEU A 120
GLU A 187
 None
 1.08A 2ya7A-3b02A:
undetectable		 2ya7A-3b02A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 6 ARG A 165
ILE A 169
LEU A 120
GLU A 187
 None
 1.03A 2ya7B-3b02A:
undetectable		 2ya7B-3b02A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 6 ARG A 165
ILE A 169
LEU A 120
GLU A 187
 None
 1.06A 2ya7D-3b02A:
undetectable		 2ya7D-3b02A:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_1
(PHOSPHOLIPASE A2)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 7 VAL A  72
GLY A  26
PRO A  47
LYS A   1
 None
 0.90A 3bjwC-3b02A:
undetectable		 3bjwC-3b02A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 8 VAL A  72
GLY A  26
PRO A  47
LYS A   1
 None
 0.92A 3bjwA-3b02A:
undetectable		 3bjwA-3b02A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		5 / 10 ILE A 145
ARG A 115
ALA A 150
VAL A 176
ILE A 169
 None
 1.09A 3falA-3b02A:
undetectable		 3falA-3b02A:
26.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 5 GLU A  15
GLY A  14
TYR A  11
GLU A  54
 None
 1.18A 3w9tA-3b02A:
undetectable		 3w9tA-3b02A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 5 GLU A  15
GLY A  14
TYR A  11
GLU A  54
 None
 1.18A 3w9tC-3b02A:
undetectable		 3w9tC-3b02A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 5 GLU A  15
GLY A  14
TYR A  11
GLU A  54
 None
 1.18A 3w9tD-3b02A:
undetectable		 3w9tD-3b02A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 5 GLU A  15
GLY A  14
TYR A  11
GLU A  54
 None
 1.18A 3w9tG-3b02A:
undetectable		 3w9tG-3b02A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 6 ARG A   3
ILE A  10
VAL A  28
LEU A  23
 None
 1.05A 4em2A-3b02A:
5.8		 4em2A-3b02A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1N_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		5 / 11 ALA A 148
LEU A 123
PHE A 122
LEU A  46
THR A 149
 None
 1.36A 4i1nA-3b02A:
undetectable		 4i1nA-3b02A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 7 HIS A 142
ILE A 116
ILE A 145
ALA A 146
 None
 0.80A 4lv9A-3b02A:
undetectable		 4lv9A-3b02A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		5 / 8 LEU A  12
GLY A  14
GLU A  53
GLU A  54
ALA A  55
 None
 1.32A 4rjdA-3b02A:
1.2
4rjdB-3b02A:
1.2		 4rjdA-3b02A:
16.49
4rjdB-3b02A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		5 / 11 LEU A 181
GLY A 135
ALA A 124
ASP A 125
SER A 129
 None
 1.36A 4wnuC-3b02A:
undetectable		 4wnuC-3b02A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		3 / 3 GLU A 144
HIS A 142
VAL A 140
 None
 0.87A 5trqB-3b02A:
undetectable		 5trqB-3b02A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY
(Thermus
thermophilus) 		4 / 8 ASP A  36
GLU A 143
VAL A 156
ARG A   6
 None
 1.19A 6fbvD-3b02A:
0.0		 6fbvD-3b02A:
10.05