SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b0b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 10 ALA C  47
THR B  24
HIS B  21
THR B  43
ALA C  48
 None
 1.42A 1gtnO-3b0bC:
undetectable
1gtnP-3b0bC:
undetectable		 1gtnO-3b0bC:
21.33
1gtnP-3b0bC:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus) 		5 / 12 PHE C  43
LEU C  75
ALA C  47
VAL B  20
THR B  24
 None
 1.19A 3cwkA-3b0bC:
undetectable		 3cwkA-3b0bC:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 10 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.21A 3fhjA-3b0bC:
undetectable		 3fhjA-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 10 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.21A 3fhjB-3b0bC:
undetectable		 3fhjB-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 10 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.18A 3fhjC-3b0bC:
undetectable		 3fhjC-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 10 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.18A 3fhjE-3b0bC:
undetectable		 3fhjE-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 9 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.24A 3fi0A-3b0bC:
undetectable		 3fi0A-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 9 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.24A 3fi0C-3b0bC:
undetectable		 3fi0C-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 9 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.21A 3fi0H-3b0bC:
undetectable		 3fi0H-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 9 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.23A 3fi0K-3b0bC:
undetectable		 3fi0K-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 9 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.24A 3fi0L-3b0bC:
undetectable		 3fi0L-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 9 GLN C  56
VAL B  37
ILE B  47
VAL C  68
VAL C  71
 None
 1.24A 3fi0N-3b0bC:
undetectable		 3fi0N-3b0bC:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 12 LEU B  12
LEU C  16
ARG C  15
THR B  51
SER B  48
 None
 1.27A 3okxA-3b0bB:
undetectable		 3okxA-3b0bB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus;
Gallus
gallus) 		5 / 12 LEU B  12
LEU C  16
ARG C  15
THR B  51
SER B  48
 None
 1.25A 3okxB-3b0bB:
undetectable		 3okxB-3b0bB:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3b0b CENTROMERE PROTEIN S
(Gallus
gallus) 		4 / 5 LEU B  82
LEU B  81
LEU B  90
SER B  86
 None
 0.84A 3vhuA-3b0bB:
undetectable		 3vhuA-3b0bB:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3b0b CENTROMERE PROTEIN S
(Gallus
gallus) 		3 / 3 LEU B 100
GLU B  99
SER B 103
 None
 0.77A 4ccqA-3b0bB:
undetectable		 4ccqA-3b0bB:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3b0b CENTROMERE PROTEIN S
CENTROMERE PROTEIN X
(Gallus
gallus) 		5 / 10 LEU B  12
HIS C  20
ALA B  59
THR C  12
LEU C  40
 None
 1.11A 5mm4B-3b0bB:
undetectable		 5mm4B-3b0bB:
18.69