SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ALA A 245
VAL A 261
TRP A 225
 None
 0.95A 1grmA-3b0hA:
undetectable		 1grmA-3b0hA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ALA A 245
VAL A 261
TRP A 225
 None
 0.95A 1grmB-3b0hA:
undetectable		 1grmB-3b0hA:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 7 GLY A 231
THR A 201
THR A 197
ILE A 230
 None
 0.98A 1gtnF-3b0hA:
undetectable
1gtnG-3b0hA:
undetectable		 1gtnF-3b0hA:
9.53
1gtnG-3b0hA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 7 GLY A 231
THR A 201
THR A 197
ILE A 230
 None
 0.95A 1gtnJ-3b0hA:
undetectable
1gtnK-3b0hA:
undetectable		 1gtnJ-3b0hA:
9.53
1gtnK-3b0hA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ALA A 245
VAL A 227
TRP A 225
 None
 0.88A 1kqeA-3b0hA:
undetectable
1kqeE-3b0hA:
undetectable		 1kqeA-3b0hA:
2.93
1kqeE-3b0hA:
2.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 12 LEU A 171
LEU A 163
ALA A 138
MET A 108
LEU A  95
 None
 1.35A 1kt5A-3b0hA:
undetectable		 1kt5A-3b0hA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 LEU A 171
LEU A 163
ALA A 138
MET A 108
LEU A  95
 None
 1.36A 1kt6A-3b0hA:
undetectable		 1kt6A-3b0hA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 LEU A 171
LEU A 163
ALA A 138
MET A 108
LEU A  95
 None
 1.38A 1kt7A-3b0hA:
undetectable		 1kt7A-3b0hA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ARG A 351
ASP A 196
ASN A 202
 None
 0.94A 1nbhA-3b0hA:
undetectable		 1nbhA-3b0hA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ARG A 351
ASP A 196
ASN A 202
 None
 0.92A 1nbhD-3b0hA:
undetectable		 1nbhD-3b0hA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 8 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.95A 1os6A-3b0hA:
undetectable		 1os6A-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 10 ALA A 278
LEU A 335
GLU A 320
LEU A 260
VAL A 261
 None
 1.10A 2bxeA-3b0hA:
undetectable		 2bxeA-3b0hA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ALA A 487
GLY A 443
SER A 458
 None
SF4  A 602 ( 4.3A)
None
 0.60A 2ivuA-3b0hA:
undetectable		 2ivuA-3b0hA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 12 LEU A 418
LEU A 423
ILE A 414
LEU A 398
VAL A 140
 None
 1.09A 2pnjA-3b0hA:
undetectable		 2pnjA-3b0hA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 5 VAL A 229
TYR A 200
VAL A 195
ASP A 196
 None
 1.23A 2x45A-3b0hA:
undetectable		 2x45A-3b0hA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 5 VAL A 229
TYR A 200
VAL A 195
ASP A 196
 None
 1.32A 2x45C-3b0hA:
undetectable		 2x45C-3b0hA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 HIS A 238
ILE A 519
ASN A 437
HIS A 478
PRO A 474
 None
 1.38A 2zweA-3b0hA:
undetectable
2zweB-3b0hA:
undetectable		 2zweA-3b0hA:
19.66
2zweB-3b0hA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 HIS A 238
ILE A 519
ASN A 437
HIS A 478
PRO A 474
 None
 1.44A 2zwgA-3b0hA:
undetectable
2zwgB-3b0hA:
undetectable		 2zwgA-3b0hA:
19.66
2zwgB-3b0hA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 PRO A 222
PHE A 264
LYS A 224
 None
None
SRM  A 601 (-2.6A)
 1.07A 3bjwG-3b0hA:
undetectable		 3bjwG-3b0hA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 6 THR A 122
ILE A 404
LEU A 396
THR A 117
 None
 0.90A 3deuB-3b0hA:
undetectable		 3deuB-3b0hA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 6 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.91A 3sj1X-3b0hA:
undetectable		 3sj1X-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 12 LEU A 417
GLY A 368
ILE A 406
ILE A 404
ASP A 430
 None
 1.04A 3uj6A-3b0hA:
undetectable		 3uj6A-3b0hA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 6 GLU A 338
LEU A 260
MET A 247
ASP A 342
 None
 1.42A 4cevA-3b0hA:
undetectable
4cevB-3b0hA:
undetectable		 4cevA-3b0hA:
22.88
4cevB-3b0hA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 6 MET A 247
ASP A 342
GLU A 338
LEU A 260
 None
 1.43A 4cevA-3b0hA:
undetectable
4cevC-3b0hA:
undetectable		 4cevA-3b0hA:
22.88
4cevC-3b0hA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 6 GLU A 338
LEU A 260
MET A 247
ASP A 342
 None
 1.43A 4cevD-3b0hA:
undetectable
4cevE-3b0hA:
undetectable		 4cevD-3b0hA:
22.88
4cevE-3b0hA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 6 GLU A 338
LEU A 260
MET A 247
ASP A 342
 None
 1.40A 4cevE-3b0hA:
undetectable
4cevF-3b0hA:
undetectable		 4cevE-3b0hA:
22.88
4cevF-3b0hA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 7 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.85A 4hajA-3b0hA:
undetectable		 4hajA-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 7 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.90A 4hbfA-3b0hA:
undetectable		 4hbfA-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 7 ILE A  65
LEU A  90
PHE A 106
GLY A 104
 None
 0.93A 4hc3A-3b0hA:
undetectable		 4hc3A-3b0hA:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		3 / 3 ARG A 375
GLU A 453
ARG A 149
 None
None
SRM  A 601 (-2.9A)
 0.98A 4mwvA-3b0hA:
undetectable		 4mwvA-3b0hA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 VAL A 227
LEU A 244
LEU A 221
CYH A 289
LEU A 293
 None
 1.01A 4p65B-3b0hA:
undetectable
4p65D-3b0hA:
undetectable
4p65G-3b0hA:
undetectable
4p65H-3b0hA:
undetectable		 4p65B-3b0hA:
4.94
4p65D-3b0hA:
4.94
4p65G-3b0hA:
3.98
4p65H-3b0hA:
4.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 12 LEU A 369
SER A 428
GLY A 355
ILE A 371
GLY A 368
 None
 1.08A 4yvgA-3b0hA:
undetectable		 4yvgA-3b0hA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 5 ARG A 329
ARG A 323
GLY A 321
GLU A 320
 None
 1.22A 4z3oA-3b0hA:
4.1
4z3oB-3b0hA:
undetectable		 4z3oA-3b0hA:
21.03
4z3oB-3b0hA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 7 ARG A 329
ARG A 323
GLY A 321
GLU A 320
 None
 1.03A 5btfA-3b0hA:
0.8
5btfC-3b0hA:
0.8
5btfD-3b0hA:
undetectable		 5btfA-3b0hA:
23.73
5btfC-3b0hA:
23.73
5btfD-3b0hA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 5 ARG A 323
GLY A 321
GLU A 320
ARG A 329
 None
 1.09A 5cdqA-3b0hA:
3.5
5cdqB-3b0hA:
undetectable
5cdqC-3b0hA:
2.4		 5cdqA-3b0hA:
23.10
5cdqB-3b0hA:
15.67
5cdqC-3b0hA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 HIS A 238
ILE A 519
ASN A 437
HIS A 478
PRO A 474
 None
 1.45A 5z0hA-3b0hA:
undetectable
5z0hB-3b0hA:
undetectable		 5z0hA-3b0hA:
9.50
5z0hB-3b0hA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 HIS A 238
ILE A 519
ASN A 437
HIS A 478
PRO A 474
 None
 1.41A 5z0iA-3b0hA:
undetectable
5z0iB-3b0hA:
undetectable		 5z0iA-3b0hA:
9.50
5z0iB-3b0hA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		5 / 11 HIS A 238
ILE A 519
ASN A 437
HIS A 478
PRO A 474
 None
 1.42A 5z0jA-3b0hA:
undetectable
5z0jB-3b0hA:
undetectable		 5z0jA-3b0hA:
9.50
5z0jB-3b0hA:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3b0h NITRITE REDUCTASE
(Nicotiana
tabacum) 		4 / 7 LEU A 276
TYR A 246
VAL A 261
TRP A 225
 None
 1.28A 6g2pA-3b0hA:
undetectable		 6g2pA-3b0hA:
20.37