SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		3 / 3 TRP A1481
HIS A1231
MET A1201
 None
 1.13A 1l5qB-3b13A:
undetectable		 1l5qB-3b13A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 8 LEU A1530
LEU A1580
GLY A1581
MET A1512
 None
 0.92A 1n13A-3b13A:
undetectable
1n13F-3b13A:
undetectable		 1n13A-3b13A:
8.06
1n13F-3b13A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 7 LEU A1530
LEU A1580
GLY A1581
MET A1512
 None
 0.93A 1n13G-3b13A:
undetectable
1n13J-3b13A:
undetectable		 1n13G-3b13A:
8.06
1n13J-3b13A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 7 GLN A1440
ALA A1472
PHE A1442
ARG A1364
 None
 1.13A 1t9wA-3b13A:
undetectable		 1t9wA-3b13A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 5 ALA A1549
PHE A1550
ASN A1457
ASP A1454
 None
 1.17A 1yc2D-3b13A:
undetectable		 1yc2D-3b13A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 12 LEU A1244
LEU A1479
LEU A1208
LEU A1227
ILE A1221
 None
 0.92A 2ouzA-3b13A:
undetectable		 2ouzA-3b13A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 8 MET A1512
LEU A1530
LEU A1580
GLY A1581
 None
 0.88A 2qqdB-3b13A:
undetectable
2qqdC-3b13A:
undetectable		 2qqdB-3b13A:
14.49
2qqdC-3b13A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 12 VAL A1591
GLY A1583
TYR A1516
ILE A1509
GLN A1576
 None
 1.46A 3bwyA-3b13A:
undetectable		 3bwyA-3b13A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 5 ASP A1341
ARG A1480
VAL A1345
THR A1471
 None
 1.24A 3eigA-3b13A:
undetectable		 3eigA-3b13A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 5 ASP A1314
GLU A1316
TYR A1308
GLU A1278
 None
 1.33A 3w9tA-3b13A:
undetectable		 3w9tA-3b13A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_ACTA1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 9 PRO A1394
GLN A1407
GLY A1346
VAL A1360
ASN A1358
 None
 1.03A 4a3uA-3b13A:
undetectable		 4a3uA-3b13A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_ACTB1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 7 PRO A1394
GLN A1407
GLY A1346
VAL A1360
 None
 0.81A 4a3uB-3b13A:
undetectable		 4a3uB-3b13A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 7 SER A1436
VAL A1439
TYR A1342
ARG A1364
 None
 1.12A 4ijiH-3b13A:
3.9		 4ijiH-3b13A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 10 ILE A1534
PHE A1579
VAL A1535
TRP A1575
ILE A1577
 None
 1.17A 5lg3H-3b13A:
1.0		 5lg3H-3b13A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 12 ILE A1534
PHE A1579
VAL A1535
TRP A1575
ILE A1577
 None
 1.15A 5lg3J-3b13A:
undetectable		 5lg3J-3b13A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		3 / 3 LYS A1252
TRP A1253
SER A1254
 None
 1.40A 5nwwA-3b13A:
undetectable		 5nwwA-3b13A:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 7 SER A1202
LEU A1479
ILE A1362
LEU A1475
 None
 1.04A 5te8A-3b13A:
undetectable		 5te8A-3b13A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		4 / 5 MET A1388
TYR A1348
GLY A1349
GLY A1351
 None
 1.20A 5x7pA-3b13A:
undetectable		 5x7pA-3b13A:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2
(Homo
sapiens) 		5 / 10 TYR A1438
TYR A1242
THR A1238
GLY A1291
GLU A1367
 None
 1.27A 6mb9D-3b13A:
undetectable		 6mb9D-3b13A:
10.07