SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus;
Aquifex
aeolicus) 		4 / 6 PRO A 255
GLU B 300
LYS B 294
VAL B 296
 None
 0.90A 1l2iB-3b1sA:
undetectable		 1l2iB-3b1sA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 12 VAL B 322
GLY B 287
ILE B 267
VAL B 320
VAL B 283
 None
 0.93A 2ieoB-3b1sB:
undetectable		 2ieoB-3b1sB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 9 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 1.02A 2o4pB-3b1sB:
undetectable		 2o4pB-3b1sB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 11 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 1.05A 2qhcA-3b1sB:
undetectable		 2qhcA-3b1sB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 12 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 1.01A 2qhcB-3b1sB:
undetectable		 2qhcB-3b1sB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 12 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 0.99A 2z54A-3b1sB:
undetectable		 2z54A-3b1sB:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 12 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 1.00A 3ndwA-3b1sB:
undetectable		 3ndwA-3b1sB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		4 / 5 VAL B 334
LEU B 312
ILE A 261
VAL B 320
 None
 0.89A 4a9kB-3b1sB:
undetectable		 4a9kB-3b1sB:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 10 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 0.94A 4dqbB-3b1sB:
undetectable		 4dqbB-3b1sB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 10 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 0.97A 4dqeB-3b1sB:
undetectable		 4dqeB-3b1sB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 10 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 0.96A 4dqhB-3b1sB:
undetectable		 4dqhB-3b1sB:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3b1s FLAGELLAR
BIOSYNTHETIC PROTEIN
FLHB
(Aquifex
aeolicus) 		5 / 12 ALA B 270
VAL B 322
GLY B 287
ILE B 267
VAL B 320
 None
 0.92A 6dgxA-3b1sB:
undetectable		 6dgxA-3b1sB:
21.88