SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 7 ASN A 318
TYR A 322
ASN A 158
TYR A 316
 NAD  A 340 (-4.2A)
NAD  A 340 ( 3.6A)
None
None
 0.96A 1dssG-3b20A:
49.0		 1dssG-3b20A:
45.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		7 / 7 SER A 154
THR A 156
ASN A 158
CYH A 159
TYR A 316
ASN A 318
TYR A 322
 SO4  A1339 (-2.7A)
SO4  A1339 (-3.7A)
None
None
None
NAD  A 340 (-4.2A)
NAD  A 340 ( 3.6A)
 0.27A 1dssG-3b20A:
49.0		 1dssG-3b20A:
45.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 8 ASN A 318
TYR A 322
ASN A 158
TYR A 316
 NAD  A 340 (-4.2A)
NAD  A 340 ( 3.6A)
None
None
 0.95A 1dssR-3b20A:
48.8		 1dssR-3b20A:
45.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		8 / 8 SER A 154
THR A 156
ASN A 158
CYH A 159
HIS A 182
TYR A 316
ASN A 318
TYR A 322
 SO4  A1339 (-2.7A)
SO4  A1339 (-3.7A)
None
None
None
None
NAD  A 340 (-4.2A)
NAD  A 340 ( 3.6A)
 0.39A 1dssR-3b20A:
48.8		 1dssR-3b20A:
45.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 4 THR A 156
LEU A 160
VAL A 163
LEU A 167
 SO4  A1339 (-3.7A)
None
None
None
 0.75A 1fbmD-3b20A:
undetectable		 1fbmD-3b20A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 5 THR A 156
LEU A 160
VAL A 163
LEU A 167
 SO4  A1339 (-3.7A)
None
None
None
 0.59A 1fbmE-3b20A:
undetectable		 1fbmE-3b20A:
9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 7 THR A 185
GLU A 319
SER A 243
VAL A 245
 SO4  A1340 (-3.0A)
None
None
None
 1.08A 1tv8B-3b20A:
undetectable		 1tv8B-3b20A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		5 / 11 ASN A 138
VAL A 134
ILE A 121
TYR A 322
ASP A 146
 None
None
None
NAD  A 340 ( 3.6A)
None
 1.44A 2iyfA-3b20A:
6.7		 2iyfA-3b20A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 5 LEU A 247
LEU A 264
CYH A 159
THR A 156
 None
None
None
SO4  A1339 (-3.7A)
 1.35A 2oaxD-3b20A:
undetectable		 2oaxD-3b20A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		3 / 3 GLY A 136
ASP A 139
SER A 140
 None
 0.47A 3brfA-3b20A:
undetectable		 3brfA-3b20A:
21.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 8 ASN A 318
TYR A 322
ASN A 158
TYR A 316
 NAD  A 340 (-4.2A)
NAD  A 340 ( 3.6A)
None
None
 0.98A 3dmtC-3b20A:
48.9		 3dmtC-3b20A:
47.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		8 / 8 SER A 154
THR A 156
ASN A 158
CYH A 159
HIS A 182
TYR A 316
ASN A 318
TYR A 322
 SO4  A1339 (-2.7A)
SO4  A1339 (-3.7A)
None
None
None
None
NAD  A 340 (-4.2A)
NAD  A 340 ( 3.6A)
 0.29A 3dmtC-3b20A:
48.9		 3dmtC-3b20A:
47.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		5 / 11 ILE A 121
ALA A 108
GLY A 107
GLU A 106
GLY A 115
 None
 1.28A 4jdsA-3b20A:
undetectable		 4jdsA-3b20A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		5 / 11 SER A 154
LEU A 160
PRO A 162
VAL A 134
THR A 132
 SO4  A1339 (-2.7A)
None
None
None
None
 1.20A 4uuuB-3b20A:
undetectable		 4uuuB-3b20A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 5 VAL A 101
TYR A 316
ILE A 296
THR A 239
 None
 1.32A 4ze1A-3b20A:
undetectable		 4ze1A-3b20A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		4 / 4 VAL A 310
ILE A 173
ASN A 170
VAL A 163
 None
 1.33A 5ajqA-3b20A:
undetectable		 5ajqA-3b20A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERS_A_ACTA803_0
(GEPHYRIN)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		3 / 3 THR A 157
ALA A 153
ASN A 158
 None
 0.56A 5ersA-3b20A:
undetectable		 5ersA-3b20A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		5 / 12 ILE A 223
ASN A 138
ALA A 153
ILE A 276
MET A 272
 None
 1.21A 5igyA-3b20A:
undetectable		 5igyA-3b20A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		5 / 12 ILE A 223
ASN A 138
ALA A 153
ILE A 276
MET A 272
 None
 1.24A 5ih0A-3b20A:
undetectable		 5ih0A-3b20A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		3 / 3 THR A 212
THR A 211
ARG A 200
 None
None
SO4  A1340 (-3.8A)
 0.97A 5wm2A-3b20A:
2.1		 5wm2A-3b20A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_2
(CYTOCHROME P450 2C9)		 3b20 GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE
(NADP+)
(Synechococcus
elongatus) 		3 / 3 LEU A  29
VAL A 327
ASP A 328
 None
 0.65A 5x23A-3b20A:
undetectable		 5x23A-3b20A:
19.09