SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 SER A  61
THR A  85
PHE A  81
GLU A  40
 None
 1.09A 1icuA-3b2dA:
undetectable
1icuB-3b2dA:
undetectable		 1icuA-3b2dA:
17.54
1icuB-3b2dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 PHE A  81
GLU A  40
SER A  61
THR A  85
 None
 1.04A 1icuA-3b2dA:
undetectable
1icuB-3b2dA:
undetectable		 1icuA-3b2dA:
17.54
1icuB-3b2dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 SER A  61
THR A  85
PHE A  81
GLU A  40
 None
 1.08A 1icuC-3b2dA:
undetectable
1icuD-3b2dA:
undetectable		 1icuC-3b2dA:
17.54
1icuD-3b2dA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 SER A  61
THR A  85
PHE A  81
GLU A  40
 None
 1.09A 1kqbA-3b2dA:
undetectable
1kqbB-3b2dA:
undetectable		 1kqbA-3b2dA:
16.10
1kqbB-3b2dA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 SER A  61
THR A  85
PHE A  81
GLU A  40
 None
 1.05A 1kqbC-3b2dA:
undetectable
1kqbD-3b2dA:
undetectable		 1kqbC-3b2dA:
16.10
1kqbD-3b2dA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 SER A 120
PHE A 142
ASN A 159
LEU A 121
 None
 1.05A 1lhvA-3b2dA:
undetectable		 1lhvA-3b2dA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 527
VAL A 525
VAL A 495
LEU A 498
LEU A 465
 None
 1.19A 1mx1E-3b2dA:
undetectable		 1mx1E-3b2dA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 ILE A 238
PHE A 239
SER A 264
ILE A 263
LEU A 281
 None
 1.31A 1rh3A-3b2dA:
undetectable		 1rh3A-3b2dA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.78A 1v55A-3b2dA:
undetectable
1v55J-3b2dA:
undetectable		 1v55A-3b2dA:
20.65
1v55J-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.77A 1v55N-3b2dA:
undetectable
1v55W-3b2dA:
undetectable		 1v55N-3b2dA:
20.65
1v55W-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 10 LEU A 154
LEU A 130
GLU A  94
GLU A 118
LEU A 121
 None
 1.24A 1wopA-3b2dA:
undetectable		 1wopA-3b2dA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 5 PHE A 180
LEU A 140
PHE A 206
SER A 189
 None
 1.07A 1wrkB-3b2dA:
undetectable		 1wrkB-3b2dA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 LEU A  51
LEU A  84
LEU A  44
ILE A  68
 None
 0.99A 1z95A-3b2dA:
undetectable		 1z95A-3b2dA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 PHE A 166
LEU A 156
LEU A 151
LEU A 148
 None
 0.89A 2bfpB-3b2dA:
undetectable		 2bfpB-3b2dA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.79A 2einA-3b2dA:
undetectable
2einJ-3b2dA:
undetectable		 2einA-3b2dA:
20.65
2einJ-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 10 ALA A 384
LEU A 401
LEU A 377
LEU A 361
LEU A 403
 None
 1.09A 2riwA-3b2dA:
undetectable
2riwB-3b2dA:
undetectable		 2riwA-3b2dA:
20.55
2riwB-3b2dA:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A 305
LEU A 281
PHE A 286
LEU A 313
 None
 0.97A 2vq5B-3b2dA:
undetectable		 2vq5B-3b2dA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 11 LEU A 474
LEU A 492
SER A 460
ASN A 479
LEU A 503
 None
 0.95A 2xn5A-3b2dA:
undetectable		 2xn5A-3b2dA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 ILE A 161
ILE A 164
MET A 193
PHE A 166
ILE A 133
 None
 1.00A 2ygoA-3b2dA:
undetectable		 2ygoA-3b2dA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.85A 3abkA-3b2dA:
undetectable
3abkJ-3b2dA:
undetectable		 3abkA-3b2dA:
20.65
3abkJ-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.81A 3abmN-3b2dA:
undetectable
3abmW-3b2dA:
undetectable		 3abmN-3b2dA:
20.65
3abmW-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.84A 3ag3A-3b2dA:
undetectable
3ag3J-3b2dA:
undetectable		 3ag3A-3b2dA:
20.65
3ag3J-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 GLN A 282
THR A 254
PHE A 297
ASN A 331
LEU A 328
 None
 1.36A 3aodC-3b2dA:
undetectable		 3aodC-3b2dA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.81A 3asoN-3b2dA:
undetectable
3asoW-3b2dA:
undetectable		 3asoN-3b2dA:
20.65
3asoW-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 GLY A 507
CYH A 506
SER A 504
ILE A 502
LEU A 501
 None
 1.01A 3cs8A-3b2dA:
undetectable		 3cs8A-3b2dA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 596
LEU A 566
LEU A 548
SER A 602
GLY A 601
 None
 1.07A 3g2oA-3b2dA:
undetectable		 3g2oA-3b2dA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 LEU A 281
LEU A 313
ILE A 263
PHE A 286
 None
 0.95A 3ln1A-3b2dA:
undetectable		 3ln1A-3b2dA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 LEU A 540
SER A 541
LEU A 574
ILE A 546
 None
 0.75A 3ln1A-3b2dA:
undetectable		 3ln1A-3b2dA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 LEU A 574
SER A 575
LEU A 589
ILE A 555
 None
 0.94A 3ln1A-3b2dA:
undetectable		 3ln1A-3b2dA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A 281
LEU A 313
ILE A 263
PHE A 286
 None
 0.93A 3ln1B-3b2dA:
undetectable		 3ln1B-3b2dA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A 540
SER A 541
LEU A 574
ILE A 546
 None
 0.76A 3ln1B-3b2dA:
undetectable		 3ln1B-3b2dA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A 574
SER A 575
LEU A 589
ILE A 555
 None
 0.95A 3ln1B-3b2dA:
undetectable		 3ln1B-3b2dA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QT0_A_486A4_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 SER A 528
ALA A 551
TYR A 547
LEU A 548
ILE A 511
 None
 1.36A 3qt0A-3b2dA:
undetectable		 3qt0A-3b2dA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_B_CVIB301_0
(PUTATIVE REGULATORY
PROTEIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 140
ILE A 185
ALA A 172
LEU A 196
LEU A 227
 None
 1.20A 3vw1B-3b2dA:
undetectable		 3vw1B-3b2dA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 5 HIS A  69
LEU A 106
LEU A  79
ASP A  83
 None
 1.33A 4aqlA-3b2dA:
undetectable		 4aqlA-3b2dA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3b2d LYMPHOCYTE ANTIGEN
86
(Homo
sapiens) 		3 / 3 LEU C  38
GLU C  39
SER C  36
 None
 0.83A 4ccqA-3b2dC:
undetectable		 4ccqA-3b2dC:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		3 / 3 TYR A 351
THR A 374
GLU A 302
 None
 0.68A 4df3A-3b2dA:
undetectable		 4df3A-3b2dA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		3 / 3 TYR A 351
THR A 374
GLU A 302
 None
 0.67A 4df3B-3b2dA:
undetectable		 4df3B-3b2dA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3b2d CD180 ANTIGEN
LYMPHOCYTE ANTIGEN
86
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ASP A 260
LEU A 235
GLY A 231
SER C 110
ILE A 258
 None
 1.44A 4djeA-3b2dA:
undetectable		 4djeA-3b2dA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_B_0LAB602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 LEU A 106
LEU A 130
ILE A 143
MET A 116
 None
 0.97A 4do3B-3b2dA:
undetectable		 4do3B-3b2dA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3b2d LYMPHOCYTE ANTIGEN
86
(Homo
sapiens) 		5 / 12 VAL C  40
ALA C 157
LEU C 142
PHE C 131
LEU C  62
 None
 1.16A 4eckB-3b2dC:
undetectable		 4eckB-3b2dC:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 599
LEU A 574
ASN A 573
LEU A 550
ALA A 551
 None
 1.23A 4fn9B-3b2dA:
undetectable		 4fn9B-3b2dA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_B_SAMB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3b2d LYMPHOCYTE ANTIGEN
86
(Homo
sapiens) 		5 / 12 GLY C  71
GLY C  52
ILE C  73
ILE C 120
ARG C  69
 None
 1.16A 4iv0B-3b2dC:
undetectable		 4iv0B-3b2dC:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 9 THR A 308
LEU A 305
GLN A 295
PHE A 294
LEU A 281
 None
 1.28A 4ltwA-3b2dA:
undetectable		 4ltwA-3b2dA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 ALA A 415
LEU A 425
THR A 430
LEU A 427
 None
 0.78A 4o0uA-3b2dA:
undetectable		 4o0uA-3b2dA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 LEU A  84
ASN A 111
HIS A  93
ILE A 114
 None
 1.02A 4ok1A-3b2dA:
undetectable		 4ok1A-3b2dA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 PHE A 441
ILE A 434
LEU A 457
LEU A 471
LEU A 465
 None
 1.30A 4qynB-3b2dA:
undetectable		 4qynB-3b2dA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 377
LEU A 395
LEU A 350
ALA A 341
ILE A 339
 None
 1.03A 4x1iD-3b2dA:
undetectable		 4x1iD-3b2dA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 377
LEU A 395
LEU A 350
ALA A 341
ILE A 339
 None
 1.02A 4x1yD-3b2dA:
undetectable		 4x1yD-3b2dA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 11 LEU A 377
LEU A 395
LEU A 350
ALA A 341
ILE A 339
 None
 1.02A 4x20D-3b2dA:
undetectable		 4x20D-3b2dA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 3b2d CD180 ANTIGEN
LYMPHOCYTE ANTIGEN
86
(Homo
sapiens) 		4 / 4 PHE A  62
ASP A  83
GLY C 117
SER A  61
 None
 1.36A 4xp9C-3b2dA:
undetectable		 4xp9C-3b2dA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 10 LEU A 474
LEU A 492
SER A 460
ASN A 479
LEU A 503
 None
 1.02A 4yiaA-3b2dA:
undetectable		 4yiaA-3b2dA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		6 / 10 LEU A 452
THR A 459
LEU A 457
LEU A 464
LEU A 465
LEU A 474
 None
 1.47A 4z91A-3b2dA:
undetectable
4z91B-3b2dA:
undetectable
4z91C-3b2dA:
undetectable
4z91D-3b2dA:
undetectable
4z91E-3b2dA:
undetectable		 4z91A-3b2dA:
19.67
4z91B-3b2dA:
19.67
4z91C-3b2dA:
19.67
4z91D-3b2dA:
19.67
4z91E-3b2dA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		6 / 10 THR A 459
LEU A 457
LEU A 464
LEU A 465
LEU A 474
LEU A 452
 None
 1.50A 4z91A-3b2dA:
undetectable
4z91B-3b2dA:
undetectable
4z91C-3b2dA:
undetectable
4z91D-3b2dA:
undetectable
4z91E-3b2dA:
undetectable		 4z91A-3b2dA:
19.67
4z91B-3b2dA:
19.67
4z91C-3b2dA:
19.67
4z91D-3b2dA:
19.67
4z91E-3b2dA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A 503
ARG A 472
MET A 522
LEU A 519
 None
 0.90A 5b1aA-3b2dA:
undetectable
5b1aJ-3b2dA:
undetectable		 5b1aA-3b2dA:
20.65
5b1aJ-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A 503
ARG A 472
MET A 522
LEU A 519
 None
 0.90A 5b3sA-3b2dA:
undetectable
5b3sJ-3b2dA:
undetectable		 5b3sA-3b2dA:
20.65
5b3sJ-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 5 LEU A 508
HIS A 480
THR A 459
CYH A 506
 None
 1.49A 5eu8A-3b2dA:
0.0		 5eu8A-3b2dA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 5 LEU A 411
LEU A 464
PHE A 416
LEU A 450
 None
 1.05A 5gtrA-3b2dA:
undetectable		 5gtrA-3b2dA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3b2d CD180 ANTIGEN
LYMPHOCYTE ANTIGEN
86
(Homo
sapiens) 		4 / 8 GLN A 134
ILE C  73
GLY A 110
THR A  85
 None
 0.81A 5hwaA-3b2dA:
undetectable		 5hwaA-3b2dA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 PHE A 229
VAL A 211
MET A 193
ILE A 164
 None
 1.05A 5iwuA-3b2dA:
undetectable		 5iwuA-3b2dA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		3 / 3 LYS A 165
ASP A 192
ARG A 194
 None
 0.88A 5jwaA-3b2dA:
undetectable
5jwaH-3b2dA:
undetectable		 5jwaA-3b2dA:
23.24
5jwaH-3b2dA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 PHE A 166
PRO A 167
MET A 116
ILE A 137
LEU A 148
 None
 1.39A 5ljbA-3b2dA:
undetectable		 5ljbA-3b2dA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 THR A 571
ILE A 546
GLY A 545
LEU A 574
LEU A 566
 None
 1.02A 5nfjA-3b2dA:
undetectable		 5nfjA-3b2dA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 9 LEU A 121
VAL A 145
LEU A 148
ILE A 137
PRO A 167
 None
 1.01A 5og9A-3b2dA:
undetectable		 5og9A-3b2dA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_B_TESB502_1
(-)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 121
VAL A 145
LEU A 148
ILE A 137
PRO A 167
 None
 1.02A 5og9B-3b2dA:
undetectable		 5og9B-3b2dA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A  51
LEU A  79
ILE A  68
LEU A  84
HIS A  69
 None
 1.05A 5toaB-3b2dA:
undetectable		 5toaB-3b2dA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A  84
THR A  55
THR A  67
ARG A  75
 None
 1.04A 5vc0A-3b2dA:
undetectable		 5vc0A-3b2dA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b2d LYMPHOCYTE ANTIGEN
86
(Homo
sapiens) 		5 / 9 LEU C  87
VAL C 140
ILE C 133
PHE C  53
ILE C  68
 None
 0.94A 5vkqC-3b2dC:
undetectable
5vkqD-3b2dC:
undetectable		 5vkqC-3b2dC:
5.92
5vkqD-3b2dC:
5.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 8 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.88A 5zcpN-3b2dA:
undetectable
5zcpW-3b2dA:
undetectable		 5zcpN-3b2dA:
20.65
5zcpW-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 LEU A 503
ARG A 472
MET A 522
LEU A 519
 None
 0.94A 5zcqA-3b2dA:
undetectable
5zcqJ-3b2dA:
undetectable		 5zcqA-3b2dA:
20.65
5zcqJ-3b2dA:
7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 ASN A 490
PHE A 481
LEU A 501
SER A 539
 None
 1.44A 6a7pB-3b2dA:
undetectable		 6a7pB-3b2dA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 PHE A 224
LEU A 204
ILE A 143
ALA A 199
 None
 0.73A 6b5vA-3b2dA:
undetectable
6b5vC-3b2dA:
undetectable		 6b5vA-3b2dA:
9.33
6b5vC-3b2dA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 ALA A 199
PHE A 224
LEU A 204
ILE A 143
 None
 0.75A 6b5vA-3b2dA:
undetectable
6b5vB-3b2dA:
undetectable		 6b5vA-3b2dA:
9.33
6b5vB-3b2dA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 PHE A 224
LEU A 204
ILE A 143
ALA A 199
 None
 0.73A 6b5vC-3b2dA:
undetectable
6b5vD-3b2dA:
undetectable		 6b5vC-3b2dA:
9.33
6b5vD-3b2dA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 7 ALA A 199
PHE A 224
LEU A 204
ILE A 143
 None
 0.74A 6b5vB-3b2dA:
undetectable
6b5vD-3b2dA:
undetectable		 6b5vB-3b2dA:
9.33
6b5vD-3b2dA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 6 GLN A 282
GLU A 256
HIS A 309
ALA A 307
 None
 1.16A 6f6jC-3b2dA:
undetectable
6f6jD-3b2dA:
undetectable		 6f6jC-3b2dA:
19.24
6f6jD-3b2dA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b2d CD180 ANTIGEN
(Homo
sapiens) 		4 / 5 ILE A 352
LEU A 377
THR A 348
LEU A 372
 None
 0.73A 6nmpN-3b2dA:
undetectable
6nmpW-3b2dA:
undetectable		 6nmpN-3b2dA:
20.65
6nmpW-3b2dA:
7.13