SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b2y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 8 ALA A 262
LEU A 195
LEU A 166
ALA A 242
 None
 0.79A 1e7cA-3b2yA:
undetectable		 1e7cA-3b2yA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		5 / 9 PHE A 232
PHE A  74
VAL A 108
LEU A 105
PHE A 130
 None
 1.44A 1wrkA-3b2yA:
undetectable
1wrkB-3b2yA:
undetectable		 1wrkA-3b2yA:
16.93
1wrkB-3b2yA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		5 / 11 LEU A  69
ILE A  53
PRO A 110
ASN A 109
LEU A  40
 None
 0.99A 2ft9A-3b2yA:
undetectable		 2ft9A-3b2yA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 8 ASP A 171
TYR A 180
TYR A 178
HIS A 224
 None
 1.29A 2ha2A-3b2yA:
undetectable		 2ha2A-3b2yA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 8 ASP A 171
TYR A 180
TYR A 178
HIS A 224
 None
 1.26A 2ha2B-3b2yA:
undetectable		 2ha2B-3b2yA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_A_REAA1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		5 / 12 THR A 246
ALA A 262
LEU A 195
ALA A 242
GLY A  73
 None
 1.08A 2ve3A-3b2yA:
undetectable		 2ve3A-3b2yA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 6 HIS A 153
GLN A  57
LEU A  45
LEU A  55
 None
 1.05A 3bgdA-3b2yA:
undetectable		 3bgdA-3b2yA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 5 GLN A 186
THR A 187
HIS A 269
LEU A 240
 None
 1.38A 4lvcA-3b2yA:
undetectable		 4lvcA-3b2yA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 5 GLN A 186
THR A 187
HIS A 269
LEU A 240
 None
 1.36A 4lvcC-3b2yA:
undetectable		 4lvcC-3b2yA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 5 GLY A 112
THR A 111
HIS A 117
GLY A 123
 None
 0.93A 4v20A-3b2yA:
undetectable		 4v20A-3b2yA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 8 GLY A 264
GLN A 265
TYR A 202
SER A 260
 None
 0.92A 4wryA-3b2yA:
2.7		 4wryA-3b2yA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRZ_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 8 GLY A 264
GLN A 265
TYR A 202
SER A 260
 None
 0.92A 4wrzA-3b2yA:
2.4		 4wrzA-3b2yA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 7 GLY A 264
GLN A 265
TYR A 202
SER A 260
 None
 0.90A 4ws0A-3b2yA:
undetectable		 4ws0A-3b2yA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 8 GLY A 264
GLN A 265
TYR A 202
SER A 260
 None
 0.90A 4ws1A-3b2yA:
2.1		 4ws1A-3b2yA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 8 LEU A  69
THR A 167
LEU A 150
LEU A 157
 None
 0.75A 4z90F-3b2yA:
undetectable
4z90G-3b2yA:
undetectable
4z90H-3b2yA:
undetectable
4z90I-3b2yA:
undetectable
4z90J-3b2yA:
undetectable		 4z90F-3b2yA:
20.18
4z90G-3b2yA:
20.18
4z90H-3b2yA:
20.18
4z90I-3b2yA:
20.18
4z90J-3b2yA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 4 GLN A 186
THR A 187
HIS A 269
LEU A 240
 None
 1.37A 6f3nB-3b2yA:
undetectable		 6f3nB-3b2yA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 5 GLN A 186
THR A 187
HIS A 269
LEU A 240
 None
 1.38A 6gbnA-3b2yA:
2.8		 6gbnA-3b2yA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3b2y METALLOPEPTIDASE
CONTAINING
CO-CATALYTIC
METALLOACTIVE SITE
(Shewanella
denitrificans) 		4 / 7 HIS A 169
THR A 167
HIS A 117
GLU A  78
 NI  A 275 (-3.3A)
None
None
NI  A 275 (-1.8A)
 1.25A 6mn4E-3b2yA:
undetectable		 6mn4E-3b2yA:
24.13