SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b2z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 11 SER A 325
THR A 326
THR A 358
ILE A 347
VAL A 348
 None
 1.04A 1pkvA-3b2zA:
undetectable
1pkvB-3b2zA:
undetectable		 1pkvA-3b2zA:
16.22
1pkvB-3b2zA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 11 ILE A 347
VAL A 348
SER A 325
THR A 326
THR A 358
 None
 1.02A 1pkvA-3b2zA:
undetectable
1pkvB-3b2zA:
undetectable		 1pkvA-3b2zA:
16.22
1pkvB-3b2zA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.75A 2eimA-3b2zA:
undetectable		 2eimA-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.72A 2einN-3b2zA:
undetectable		 2einN-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 ARG A 318
GLY A 454
PRO A 455
 None
 0.75A 2hreD-3b2zA:
2.3		 2hreD-3b2zA:
19.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_A_097A1001_1
(ADAMTS-1)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 9 LEU A 330
THR A 358
HIS A 361
HIS A 365
HIS A 371
 None
None
ZN  A   1 (-3.0A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.2A)
 0.48A 2jihA-3b2zA:
41.1		 2jihA-3b2zA:
59.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JIH_B_097B1001_1
(ADAMTS-1)		 3b2z ADAMTS-4
(Homo
sapiens) 		4 / 8 THR A 358
HIS A 361
HIS A 365
HIS A 371
 None
ZN  A   1 (-3.0A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.2A)
 0.25A 2jihB-3b2zA:
41.2		 2jihB-3b2zA:
59.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 12 SER A 408
ASN A 381
THR A 337
ALA A 360
VAL A 398
 None
 1.29A 2nniA-3b2zA:
undetectable		 2nniA-3b2zA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 361
HIS A 365
HIS A 371
 ZN  A   1 (-3.0A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.2A)
 0.24A 2ozrF-3b2zA:
9.7		 2ozrF-3b2zA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 12 GLY A 504
LEU A 470
ALA A 490
ASP A 491
ALA A 445
 None
 1.01A 2yqzA-3b2zA:
undetectable		 2yqzA-3b2zA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.75A 3bvdA-3b2zA:
undetectable		 3bvdA-3b2zA:
19.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 9 LEU A 330
THR A 358
HIS A 361
HIS A 365
HIS A 371
 None
None
ZN  A   1 (-3.0A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.2A)
 0.46A 3hy7A-3b2zA:
33.6		 3hy7A-3b2zA:
36.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 9 LEU A 330
THR A 358
HIS A 361
HIS A 365
HIS A 371
 None
None
ZN  A   1 (-3.0A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.2A)
 0.54A 3hy7B-3b2zA:
32.7		 3hy7B-3b2zA:
36.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.79A 3s33A-3b2zA:
undetectable		 3s33A-3b2zA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.74A 3s38A-3b2zA:
undetectable		 3s38A-3b2zA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.79A 3s3aA-3b2zA:
undetectable		 3s3aA-3b2zA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.81A 3s3bA-3b2zA:
undetectable		 3s3bA-3b2zA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3b2z ADAMTS-4
(Homo
sapiens) 		4 / 7 ASN A 373
ASP A 328
HIS A 365
HIS A 361
 None
ZN  A   1 (-1.9A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.93A 3t01A-3b2zA:
undetectable		 3t01A-3b2zA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.76A 3wg7N-3b2zA:
undetectable		 3wg7N-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.73A 3x2qN-3b2zA:
undetectable		 3x2qN-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 12 PHE A 367
GLY A 336
VAL A 335
SER A 408
TRP A 404
 None
 1.23A 4bvaA-3b2zA:
undetectable		 4bvaA-3b2zA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 11 VAL A 338
VAL A 366
ILE A 258
ILE A 412
LEU A 424
 None
 1.10A 5e4dB-3b2zA:
undetectable		 5e4dB-3b2zA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.54A 5qgjA-3b2zA:
undetectable		 5qgjA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.66A 5qglA-3b2zA:
undetectable		 5qglA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.49A 5qgmA-3b2zA:
undetectable		 5qgmA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.58A 5qgnA-3b2zA:
undetectable		 5qgnA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.60A 5qguA-3b2zA:
undetectable		 5qguA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.60A 5qgvA-3b2zA:
undetectable		 5qgvA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.60A 5qgwA-3b2zA:
undetectable		 5qgwA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.60A 5qgxA-3b2zA:
undetectable		 5qgxA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.60A 5qgyA-3b2zA:
undetectable		 5qgyA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.59A 5qgzA-3b2zA:
undetectable		 5qgzA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.60A 5qh0A-3b2zA:
undetectable		 5qh0A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.61A 5qh1A-3b2zA:
undetectable		 5qh1A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.62A 5qh2A-3b2zA:
undetectable		 5qh2A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.59A 5qh3A-3b2zA:
undetectable		 5qh3A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.58A 5qh4A-3b2zA:
undetectable		 5qh4A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.56A 5qh5A-3b2zA:
undetectable		 5qh5A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.56A 5qh6A-3b2zA:
undetectable		 5qh6A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.58A 5qh7A-3b2zA:
undetectable		 5qh7A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.54A 5qh9A-3b2zA:
undetectable		 5qh9A-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.60A 5qhaA-3b2zA:
undetectable		 5qhaA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.58A 5qhcA-3b2zA:
undetectable		 5qhcA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.59A 5qheA-3b2zA:
undetectable		 5qheA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.57A 5qhfA-3b2zA:
undetectable		 5qhfA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.56A 5qhgA-3b2zA:
undetectable		 5qhgA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 VAL A 270
VAL A 225
GLN A 296
 None
 0.57A 5qhhA-3b2zA:
undetectable		 5qhhA-3b2zA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 12 MET A 246
ALA A 252
PHE A 253
VAL A 266
VAL A 366
 None
 1.28A 5tudD-3b2zA:
undetectable		 5tudD-3b2zA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.74A 5w97a-3b2zA:
undetectable		 5w97a-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.69A 5x1bN-3b2zA:
undetectable		 5x1bN-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.67A 5x1fN-3b2zA:
undetectable		 5x1fN-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.77A 5z85N-3b2zA:
undetectable		 5z85N-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b2z ADAMTS-4
(Homo
sapiens) 		3 / 3 HIS A 371
HIS A 365
HIS A 361
 ZN  A   1 (-3.2A)
ZN  A   1 (-3.3A)
ZN  A   1 (-3.0A)
 0.74A 5zcoN-3b2zA:
undetectable		 5zcoN-3b2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3b2z ADAMTS-4
(Homo
sapiens) 		5 / 9 PHE A 316
ASP A 351
VAL A 324
SER A 325
ASP A 320
 None
 1.34A 6c2mD-3b2zA:
undetectable		 6c2mD-3b2zA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3b2z ADAMTS-4
(Homo
sapiens) 		4 / 4 ALA A 249
ALA A 252
ALA A 360
ALA A 359
 None
 0.82A 6gtqA-3b2zA:
undetectable
6gtqB-3b2zA:
undetectable		 6gtqA-3b2zA:
20.90
6gtqB-3b2zA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA205_0
(N-ACETYLTRANSFERASE)		 3b2z ADAMTS-4
(Homo
sapiens) 		4 / 4 ALA A 360
ALA A 359
ALA A 249
ALA A 252
 None
 0.81A 6gtqA-3b2zA:
undetectable
6gtqB-3b2zA:
undetectable		 6gtqA-3b2zA:
20.90
6gtqB-3b2zA:
20.90