SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3b32 CALMODULIN
(Rattus
norvegicus) 		5 / 11 ILE A  27
LEU A  32
MET A  51
VAL A  55
MET A  71
 None
 0.97A 1dtlA-3b32A:
11.6		 1dtlA-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3b32 CALMODULIN
(Rattus
norvegicus) 		7 / 11 PHE A  19
ILE A  27
LEU A  32
MET A  36
LEU A  39
MET A  51
VAL A  55
 None
 0.63A 1dtlA-3b32A:
11.6		 1dtlA-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 3b32 CALMODULIN
(Rattus
norvegicus) 		4 / 8 MET A  36
GLN A  41
PRO A  43
GLU A  47
 None
 0.42A 1dtlA-3b32A:
11.6		 1dtlA-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		6 / 12 PHE A  19
ILE A  27
LEU A  32
MET A  36
ILE A  52
GLU A  54
 None
 0.85A 1lxfC-3b32A:
10.0		 1lxfC-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		6 / 12 PHE A  19
ILE A  27
LEU A  32
MET A  36
MET A  51
ILE A  52
 None
 0.88A 1lxfC-3b32A:
10.0		 1lxfC-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		5 / 10 MET A  36
GLN A  41
GLU A  47
MET A  51
MET A  71
 None
 1.39A 1wrkA-3b32A:
11.3
1wrkB-3b32A:
11.3		 1wrkA-3b32A:
59.30
1wrkB-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_A_TFPA202_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		5 / 10 MET A  36
LEU A  39
GLN A  41
GLU A  47
MET A  51
 None
 0.53A 1wrkA-3b32A:
11.3
1wrkB-3b32A:
11.3		 1wrkA-3b32A:
59.30
1wrkB-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		5 / 6 PHE A  19
VAL A  35
LEU A  39
PHE A  68
MET A  72
 None
 1.47A 1wrlB-3b32A:
11.4		 1wrlB-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC206_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		5 / 9 MET A  36
LEU A  39
GLN A  41
GLU A  47
MET A  51
 None
 0.63A 1wrlC-3b32A:
11.2
1wrlD-3b32A:
11.1		 1wrlC-3b32A:
59.30
1wrlD-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC206_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		5 / 9 MET A  36
LEU A  39
GLN A  41
GLU A  47
MET A  71
 None
 1.33A 1wrlC-3b32A:
11.2
1wrlD-3b32A:
11.1		 1wrlC-3b32A:
59.30
1wrlD-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		4 / 5 PHE A  19
LEU A  39
PHE A  68
MET A  72
 None
 1.04A 1wrlC-3b32A:
11.2		 1wrlC-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b32 CALMODULIN
(Rattus
norvegicus) 		4 / 7 PHE A  19
LEU A  39
PHE A  68
MET A  72
 None
 1.15A 1wrlE-3b32A:
11.2		 1wrlE-3b32A:
59.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3b32 CALMODULIN
(Rattus
norvegicus) 		4 / 8 PHE A  19
ILE A  27
LEU A  32
MET A  51
 None
 0.43A 4rjdA-3b32A:
12.9		 4rjdA-3b32A:
46.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 3b32 CALMODULIN
(Rattus
norvegicus) 		5 / 10 LEU A  32
MET A  51
GLU A  54
VAL A  55
ILE A  63
 None
 0.69A 5v02B-3b32A:
undetectable
5v02R-3b32A:
12.6		 5v02B-3b32A:
20.00
5v02R-3b32A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3b32 CALMODULIN
(Rattus
norvegicus) 		3 / 3 ALA A  73
PHE A  12
GLN A   8
 None
 0.82A 6eceA-3b32A:
undetectable		 6eceA-3b32A:
14.44