SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 ASP A  75
LEU A  63
LEU A  60
LEU A  62
 None
 1.38A 1u18A-3b33A:
undetectable		 1u18A-3b33A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 6 LEU A  60
LEU A  58
PRO A  66
VAL A  93
 None
 1.17A 2dqyC-3b33A:
undetectable		 2dqyC-3b33A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 ALA A  16
LEU A  89
VAL A  91
ILE A  53
THR A  15
 None
 1.07A 2w9hA-3b33A:
undetectable		 2w9hA-3b33A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 ALA A  16
LEU A  89
VAL A  91
ILE A  53
THR A  15
 None
 1.03A 3frbX-3b33A:
undetectable		 3frbX-3b33A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 9 ALA A  16
LEU A  89
VAL A  91
ILE A  53
THR A  15
 None
 1.02A 3freX-3b33A:
undetectable		 3freX-3b33A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 LEU A  49
LEU A  52
GLN A  54
PHE A  37
LEU A  89
 None
 1.34A 3gwuA-3b33A:
undetectable		 3gwuA-3b33A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 LEU A  35
GLU A  34
SER A  38
 None
 0.66A 4ccqA-3b33A:
undetectable		 4ccqA-3b33A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 LEU A  36
ILE A  53
LEU A  52
LEU A  89
PHE A  37
 None
 1.06A 4odoA-3b33A:
undetectable		 4odoA-3b33A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 LEU A  36
ILE A  53
LEU A  52
LEU A  89
PHE A  37
 None
 0.99A 4odoB-3b33A:
2.2		 4odoB-3b33A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 LEU A  36
ILE A  53
LEU A  52
LEU A  89
PHE A  37
 None
 1.00A 4odoC-3b33A:
undetectable		 4odoC-3b33A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 PHE A  37
ILE A  53
LEU A  20
VAL A 106
PHE A  80
 None
 1.10A 5im2A-3b33A:
undetectable		 5im2A-3b33A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3b33 SENSOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 MET A 108
ALA A  32
LEU A  35
TYR A  28
THR A  17
 None
 1.04A 5k9dA-3b33A:
undetectable		 5k9dA-3b33A:
16.71