SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		3 / 3 TRP A 193
HIS A 171
MET A 197
 None
 0.93A 1l5qB-3b3dA:
undetectable		 1l5qB-3b3dA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 PHE A  79
LEU A 112
VAL A 144
LEU A 155
LEU A  89
 None
 1.32A 2hc4A-3b3dA:
undetectable		 2hc4A-3b3dA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 6 LEU A 202
TRP A 225
MET A 259
LEU A 265
 None
 1.28A 2oz7A-3b3dA:
undetectable		 2oz7A-3b3dA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X08_A_ASCA1253_0
(CYTOCHROME C
PEROXIDASE,
MITOCHONDRIAL)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 9 ALA A 264
ASP A 263
ILE A 262
PRO A 172
HIS A 229
 None
 1.17A 2x08A-3b3dA:
0.0		 2x08A-3b3dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 11 ILE A 139
ALA A 129
ILE A 115
VAL A  84
GLY A 143
 None
 0.85A 3kw4A-3b3dA:
undetectable		 3kw4A-3b3dA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 THR A  50
LEU A 107
LEU A 105
GLY A  61
VAL A  24
 None
 1.09A 3lxiA-3b3dA:
undetectable		 3lxiA-3b3dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 11 THR A  50
LEU A 107
LEU A 105
GLY A  61
VAL A  24
 None
 1.13A 3lxiB-3b3dA:
undetectable		 3lxiB-3b3dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 9 THR A  50
LEU A 107
LEU A 105
GLY A  61
VAL A  24
 None
 1.10A 4c9kB-3b3dA:
undetectable		 4c9kB-3b3dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 8 THR A  50
LEU A 107
LEU A 105
GLY A  61
 None
 0.87A 4c9nA-3b3dA:
undetectable		 4c9nA-3b3dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 THR A  50
LEU A 107
LEU A 105
GLY A  61
VAL A  24
 None
 1.10A 4c9nB-3b3dA:
undetectable		 4c9nB-3b3dA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 9 THR A  50
LEU A 107
LEU A 105
GLY A  61
VAL A  24
 None
 1.11A 4c9pA-3b3dA:
undetectable		 4c9pA-3b3dA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 10 THR A  50
LEU A 107
LEU A 105
GLY A  61
VAL A  24
 None
 1.13A 4c9pB-3b3dA:
undetectable		 4c9pB-3b3dA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 9 ALA A  71
GLY A  72
ILE A  68
GLY A  67
ILE A  41
 None
 1.14A 4eatB-3b3dA:
undetectable		 4eatB-3b3dA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A 105
GLY A  61
ARG A  65
PHE A  79
LEU A 110
 None
 1.34A 5czyA-3b3dA:
undetectable		 5czyA-3b3dA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A 152
LEU A 174
MET A 190
LEU A 179
CYH A 183
 None
 1.12A 5emlA-3b3dA:
4.0		 5emlA-3b3dA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		4 / 7 LEU A 207
LYS A 177
ILE A 180
THR A 175
 None
 1.38A 5ljcA-3b3dA:
undetectable		 5ljcA-3b3dA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 THR A  50
ALA A  51
ILE A 234
GLY A  23
LEU A 114
 None
 0.80A 5nfjA-3b3dA:
2.3		 5nfjA-3b3dA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		6 / 12 LEU A 110
GLY A 106
ILE A  48
VAL A  37
GLY A  59
ILE A  80
 None
 1.24A 5t8hB-3b3dA:
undetectable		 5t8hB-3b3dA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A 196
ASP A  49
GLY A  21
PHE A  20
ILE A 165
 CA  A 281 (-4.2A)
None
None
None
None
 1.12A 6dwnA-3b3dA:
undetectable		 6dwnA-3b3dA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3b3d PUTATIVE MORPHINE
DEHYDROGENASE
(Bacillus
subtilis) 		5 / 12 LEU A 196
ASP A  49
GLY A  21
PHE A  20
ILE A 165
 CA  A 281 (-4.2A)
None
None
None
None
 1.11A 6dwnC-3b3dA:
undetectable		 6dwnC-3b3dA:
12.14