SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b46'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.89A 1v55N-3b46A:
undetectable
1v55W-3b46A:
undetectable		 1v55N-3b46A:
22.55
1v55W-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		3 / 3 ARG A  94
SER A 106
TYR A 105
 None
 0.58A 1x70A-3b46A:
undetectable		 1x70A-3b46A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.91A 2einA-3b46A:
undetectable
2einJ-3b46A:
undetectable		 2einA-3b46A:
22.55
2einJ-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 11 SER A 130
ALA A 297
ALA A 124
GLY A 123
THR A 122
 None
None
LLP  A 271 ( 3.4A)
LLP  A 271 ( 3.6A)
None
 1.04A 2f16H-3b46A:
undetectable
2f16I-3b46A:
undetectable		 2f16H-3b46A:
18.57
2f16I-3b46A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 11 SER A 130
ALA A 297
ALA A 124
GLY A 123
THR A 122
 None
None
LLP  A 271 ( 3.4A)
LLP  A 271 ( 3.6A)
None
 1.05A 2f16V-3b46A:
undetectable
2f16W-3b46A:
undetectable		 2f16V-3b46A:
18.57
2f16W-3b46A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 5 VAL A  34
THR A  38
VAL A 399
GLY A  60
 None
 1.10A 2p2fA-3b46A:
undetectable		 2p2fA-3b46A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 4 VAL A  34
THR A  38
VAL A 399
GLY A  60
 None
 1.11A 2p2fB-3b46A:
undetectable		 2p2fB-3b46A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.84A 2q63A-3b46A:
undetectable		 2q63A-3b46A:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.83A 2q64B-3b46A:
undetectable		 2q64B-3b46A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 351
VAL A 362
ILE A 343
ASP A 345
 None
 1.01A 2x45B-3b46A:
undetectable		 2x45B-3b46A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 351
VAL A 362
ILE A 343
ASP A 345
 None
 0.99A 2x45C-3b46A:
undetectable		 2x45C-3b46A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.84A 3abkA-3b46A:
undetectable
3abkJ-3b46A:
undetectable		 3abkA-3b46A:
22.55
3abkJ-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.83A 3ablN-3b46A:
undetectable
3ablW-3b46A:
undetectable		 3ablN-3b46A:
22.55
3ablW-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.84A 3abmN-3b46A:
undetectable
3abmW-3b46A:
undetectable		 3abmN-3b46A:
22.55
3abmW-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.84A 3asoN-3b46A:
undetectable
3asoW-3b46A:
undetectable		 3asoN-3b46A:
22.55
3asoW-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 6 THR A 119
VAL A 120
GLU A 126
SER A 305
 None
 1.17A 3b6rB-3b46A:
undetectable		 3b6rB-3b46A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 351
VAL A 362
ILE A 343
ASP A 345
 None
 1.07A 3bu1A-3b46A:
undetectable		 3bu1A-3b46A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 202
LEU A 129
ILE A 186
ILE A 143
 None
 0.77A 3gcsA-3b46A:
undetectable		 3gcsA-3b46A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.86A 3k4vB-3b46A:
undetectable		 3k4vB-3b46A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 104
TRP A 282
GLY A 267
 None
 0.72A 3l35A-3b46A:
undetectable
3l35H-3b46A:
undetectable		 3l35A-3b46A:
8.59
3l35H-3b46A:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 104
TRP A 282
GLY A 267
 None
 0.73A 3l35B-3b46A:
undetectable
3l35K-3b46A:
undetectable		 3l35B-3b46A:
8.59
3l35K-3b46A:
2.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 11 SER A 130
ALA A 297
ALA A 124
GLY A 123
THR A 122
 None
None
LLP  A 271 ( 3.4A)
LLP  A 271 ( 3.6A)
None
 1.03A 3mg0V-3b46A:
undetectable
3mg0W-3b46A:
undetectable		 3mg0V-3b46A:
18.57
3mg0W-3b46A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.85A 3ndtA-3b46A:
undetectable		 3ndtA-3b46A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.83A 3ndtB-3b46A:
undetectable		 3ndtB-3b46A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.83A 3ndtC-3b46A:
undetectable		 3ndtC-3b46A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 127
ILE A 156
VAL A 233
ILE A 235
 None
 1.01A 3nu3A-3b46A:
undetectable		 3nu3A-3b46A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.83A 3oxcB-3b46A:
undetectable		 3oxcB-3b46A:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 345
PHE A 340
VAL A 360
TYR A 351
 None
 0.98A 3pglA-3b46A:
undetectable		 3pglA-3b46A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 127
ILE A 156
VAL A 233
ILE A 235
 None
 1.00A 3pwrA-3b46A:
undetectable		 3pwrA-3b46A:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 297
ILE A 235
LEU A 264
CYH A 302
VAL A 283
 None
 0.84A 3rukA-3b46A:
undetectable		 3rukA-3b46A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.86A 3tl9A-3b46A:
undetectable		 3tl9A-3b46A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 264
GLY A 260
ALA A 253
ILE A 108
VAL A 283
 None
 0.85A 3tl9B-3b46A:
undetectable		 3tl9B-3b46A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 440
VAL A 362
TRP A 391
LEU A 396
 None
 1.11A 3v81A-3b46A:
undetectable		 3v81A-3b46A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 205
LEU A 361
PHE A 148
TYR A 407
 LLP  A 271 ( 3.2A)
None
None
None
 1.20A 4u14A-3b46A:
0.0		 4u14A-3b46A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 142
ILE A 143
LEU A 220
LEU A 223
 None
 0.96A 4xo7A-3b46A:
undetectable		 4xo7A-3b46A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  97
SER A 100
ILE A 317
SER A 316
HIS A 242
 None
 1.34A 5h1eA-3b46A:
undetectable		 5h1eA-3b46A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 9 SER A 305
GLY A  93
ALA A 295
GLU A 126
ILE A  98
 None
 1.49A 5i3cA-3b46A:
undetectable		 5i3cA-3b46A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 209
ILE A 334
TYR A 333
PHE A 326
 LLP  A 271 ( 4.1A)
None
None
None
 1.50A 5igvA-3b46A:
undetectable		 5igvA-3b46A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 290
GLY A 134
GLY A 127
ILE A 128
SER A 285
 None
 0.67A 5t2zA-3b46A:
undetectable		 5t2zA-3b46A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		3 / 3 TYR A 240
ALA A 422
TYR A 358
 LLP  A 271 ( 4.2A)
None
None
 0.83A 5uunB-3b46A:
undetectable		 5uunB-3b46A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 148
HIS A 208
PRO A 210
ILE A 211
 None
 1.01A 5vkqA-3b46A:
undetectable
5vkqD-3b46A:
undetectable		 5vkqA-3b46A:
14.39
5vkqD-3b46A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 148
HIS A 208
PRO A 210
ILE A 211
 None
 1.03A 5vkqA-3b46A:
undetectable
5vkqB-3b46A:
undetectable		 5vkqA-3b46A:
14.39
5vkqB-3b46A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 PHE A 148
HIS A 208
PRO A 210
ILE A 211
 None
 0.99A 5vkqB-3b46A:
undetectable
5vkqC-3b46A:
undetectable		 5vkqB-3b46A:
14.39
5vkqC-3b46A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 148
HIS A 208
PRO A 210
ILE A 211
 None
 1.00A 5vkqC-3b46A:
undetectable
5vkqD-3b46A:
undetectable		 5vkqC-3b46A:
14.39
5vkqD-3b46A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 400
VAL A 423
CYH A 424
PHE A 337
THR A 341
 None
 1.36A 5vlmD-3b46A:
undetectable		 5vlmD-3b46A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.81A 5xdxN-3b46A:
undetectable
5xdxW-3b46A:
undetectable		 5xdxN-3b46A:
22.55
5xdxW-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 343
LEU A 347
PHE A 344
LEU A 396
 None
 0.86A 5zcpN-3b46A:
undetectable
5zcpW-3b46A:
undetectable		 5zcpN-3b46A:
22.55
5zcpW-3b46A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 101
LEU A 104
GLY A 270
LYS A 272
 None
None
LLP  A 271 ( 2.4A)
LLP  A 271 ( 3.1A)
 0.89A 6ce2A-3b46A:
undetectable		 6ce2A-3b46A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 3b46 AMINOTRANSFERASE
BNA3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 128
TYR A 165
PHE A 148
LEU A 129
LEU A 136
 None
 1.37A 6chgC-3b46A:
undetectable		 6chgC-3b46A:
16.67