SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AM6_A_HAEA555_1 (CARBONIC ANHYDRASE)	3b47	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Geobacter sulfurreducens)	4 / 7	HIS A 119 LEU A 82 THR A 156 THR A 157	None	1.01A	1am6A-3b47A: undetectable	1am6A-3b47A: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FBX_A_ACTA608_0 (PUTATIVE PHOSPHOLIPASE B-LIKE 2)	3b47	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Geobacter sulfurreducens)	3 / 3	GLU A 136 VAL A 137 CYH A 139	None None HEM A 199 (-1.8A)	0.73A	3fbxA-3b47A: undetectable	3fbxA-3b47A: 15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	3b47	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Geobacter sulfurreducens)	5 / 12	GLY A 77 GLY A 162 ASP A 74 VAL A 75 ALA A 80	None	1.16A	5kpcB-3b47A: undetectable	5kpcB-3b47A: 16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3b47	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Geobacter sulfurreducens)	3 / 3	ARG A 85 LEU A 154 PHE A 129	None	0.65A	6nknP-3b47A: undetectable	6nknP-3b47A: 19.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AM6_A_HAEA555_1","CARBONIC ANHYDRASE","3b47","METHYL-ACCEPTING CHEMOTAXIS PROTEIN","Geobacter sulfurreducens",4,"HIS A 119;LEU A  82;THR A 156;THR A 157","None","1.01A","1am6A-3b47A:undetectable","1am6A-3b47A:19.68"],["3FBX_A_ACTA608_0","PUTATIVE PHOSPHOLIPASE B-LIKE 2","3b47","METHYL-ACCEPTING CHEMOTAXIS PROTEIN","Geobacter sulfurreducens",3,"GLU A 136;VAL A 137;CYH A 139","None;None;HEM A 199 (-1.8A)","0.73A","3fbxA-3b47A:undetectable","3fbxA-3b47A:15.84"],["5KPC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","3b47","METHYL-ACCEPTING CHEMOTAXIS PROTEIN","Geobacter sulfurreducens",5,"GLY A  77;GLY A 162;ASP A  74;VAL A  75;ALA A  80","None","1.16A","5kpcB-3b47A:undetectable","5kpcB-3b47A:16.79"],["6NKN_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3b47","METHYL-ACCEPTING CHEMOTAXIS PROTEIN","Geobacter sulfurreducens",3,"ARG A  85;LEU A 154;PHE A 129","None","0.65A","6nknP-3b47A:undetectable","6nknP-3b47A:19.92"]]