SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A  65
GLY A 102
ALA A 103
ILE A  33
ILE A   5
 None
 0.76A 2rkfB-3b48A:
undetectable		 2rkfB-3b48A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A  65
GLY A 102
ALA A 103
ILE A  33
ILE A   5
 None
 0.77A 2rkgA-3b48A:
undetectable		 2rkgA-3b48A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 9 LEU A  65
GLY A 102
ALA A 103
ILE A  33
ILE A   5
 None
 0.77A 3nu4B-3b48A:
undetectable		 3nu4B-3b48A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 9 LEU A  65
GLY A 102
ILE A  33
ILE A 108
ILE A   5
 None
 0.87A 3nu4B-3b48A:
undetectable		 3nu4B-3b48A:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A  65
GLY A 102
ALA A 103
ILE A  33
ILE A   5
 None
 0.74A 5e5jB-3b48A:
undetectable		 5e5jB-3b48A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A  65
GLY A 102
ALA A 103
ILE A  33
ILE A   5
 None
 0.75A 5e5kA-3b48A:
undetectable		 5e5kA-3b48A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A  65
GLY A 102
ILE A  33
ILE A 108
ILE A   5
 None
 0.84A 5e5kA-3b48A:
undetectable		 5e5kA-3b48A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3b48 UNCHARACTERIZED
PROTEIN
(Enterococcus
faecalis) 		5 / 12 LEU A  65
GLY A 102
ALA A 103
ILE A  33
ILE A   5
 None
 0.72A 5t8hB-3b48A:
undetectable		 5t8hB-3b48A:
23.02