SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b4u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 8 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.84A 1v55N-3b4uA:
undetectable
1v55W-3b4uA:
undetectable		 1v55N-3b4uA:
20.99
1v55W-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 7 ILE A 141
ALA A 105
GLY A  45
THR A  46
 None
 0.62A 2xrzB-3b4uA:
undetectable		 2xrzB-3b4uA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 8 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.85A 3abkA-3b4uA:
undetectable
3abkJ-3b4uA:
undetectable		 3abkA-3b4uA:
20.99
3abkJ-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 8 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.84A 3abmN-3b4uA:
undetectable
3abmW-3b4uA:
undetectable		 3abmN-3b4uA:
20.99
3abmW-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 7 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.90A 3ag3A-3b4uA:
undetectable
3ag3J-3b4uA:
undetectable		 3ag3A-3b4uA:
20.99
3ag3J-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 8 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.85A 3asoN-3b4uA:
undetectable
3asoW-3b4uA:
undetectable		 3asoN-3b4uA:
20.99
3asoW-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_1
(PHOSPHOLIPASE A2)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 10 VAL A 151
GLU A 184
GLY A 155
ARG A 180
LYS A 183
 None
 1.49A 3bjwD-3b4uA:
undetectable		 3bjwD-3b4uA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 6 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.78A 3wg7N-3b4uA:
undetectable
3wg7W-3b4uA:
undetectable		 3wg7N-3b4uA:
20.99
3wg7W-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_A_198A601_1
(SERUM ALBUMIN)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 10 PRO A  14
MET A  26
ALA A  28
PHE A  65
LEU A  43
 None
 1.40A 4la0A-3b4uA:
undetectable		 4la0A-3b4uA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 9 PRO A  14
MET A  26
ALA A  28
PHE A  65
LEU A  43
 None
 1.26A 4la0B-3b4uA:
undetectable		 4la0B-3b4uA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 4 ILE A 273
VAL A 250
VAL A 252
ARG A 278
 None
 1.09A 4m6tA-3b4uA:
undetectable		 4m6tA-3b4uA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 LEU A  43
PHE A  44
LEU A  11
VAL A 254
VAL A  21
 None
 1.38A 4mk4B-3b4uA:
0.6		 4mk4B-3b4uA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 12 GLY A 208
ALA A 225
VAL A 221
GLU A 195
SER A 171
 None
 1.10A 4pd5A-3b4uA:
undetectable		 4pd5A-3b4uA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.33A 4qvpV-3b4uA:
undetectable
4qvpb-3b4uA:
undetectable		 4qvpV-3b4uA:
24.35
4qvpb-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.33A 4qvpH-3b4uA:
undetectable
4qvpN-3b4uA:
undetectable		 4qvpH-3b4uA:
24.35
4qvpN-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.32A 4qw1V-3b4uA:
undetectable
4qw1b-3b4uA:
undetectable		 4qw1V-3b4uA:
24.35
4qw1b-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.33A 4qw1H-3b4uA:
undetectable
4qw1N-3b4uA:
undetectable		 4qw1H-3b4uA:
24.35
4qw1N-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.30A 4qwuV-3b4uA:
undetectable
4qwub-3b4uA:
undetectable		 4qwuV-3b4uA:
24.35
4qwub-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.31A 4qwuH-3b4uA:
undetectable
4qwuN-3b4uA:
undetectable		 4qwuH-3b4uA:
24.35
4qwuN-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 7 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.81A 5b1bN-3b4uA:
undetectable
5b1bW-3b4uA:
undetectable		 5b1bN-3b4uA:
20.99
5b1bW-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 7 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.83A 5b3sN-3b4uA:
0.2
5b3sW-3b4uA:
undetectable		 5b3sN-3b4uA:
20.99
5b3sW-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 5 PHE A 244
GLY A 283
ASP A 277
ILE A 273
 None
 0.96A 5ik1A-3b4uA:
undetectable		 5ik1A-3b4uA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 7 PHE A 244
GLY A 283
ASP A 277
ILE A 273
VAL A 252
 None
 1.50A 5ik1A-3b4uA:
undetectable		 5ik1A-3b4uA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.34A 5l66V-3b4uA:
undetectable
5l66b-3b4uA:
undetectable		 5l66V-3b4uA:
24.35
5l66b-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		5 / 11 SER A 211
THR A 247
GLY A  45
ALA A  10
THR A  42
 None
 1.34A 5l66H-3b4uA:
undetectable
5l66N-3b4uA:
undetectable		 5l66H-3b4uA:
24.35
5l66N-3b4uA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 7 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.89A 5xdqN-3b4uA:
undetectable
5xdqW-3b4uA:
undetectable		 5xdqN-3b4uA:
20.99
5xdqW-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 6 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.83A 5z86N-3b4uA:
undetectable
5z86W-3b4uA:
undetectable		 5z86N-3b4uA:
20.99
5z86W-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 6 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.85A 5zcoN-3b4uA:
undetectable
5zcoW-3b4uA:
undetectable		 5zcoN-3b4uA:
20.99
5zcoW-3b4uA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b4u DIHYDRODIPICOLINATE
SYNTHASE
(Agrobacterium
fabrum) 		4 / 8 ILE A  66
ARG A 100
THR A  42
LEU A  43
 None
 0.84A 5zcpN-3b4uA:
undetectable
5zcpW-3b4uA:
undetectable		 5zcpN-3b4uA:
20.99
5zcpW-3b4uA:
13.36