SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1870_0
(FPRA)		 3b4v FOLLISTATIN-LIKE 3
(Homo
sapiens) 		4 / 4 HIS C  50
PRO C  51
LYS C  54
ILE C  55
 None
 1.40A 1lqtA-3b4vC:
0.0		 1lqtA-3b4vC:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1427_0
(FPRA)		 3b4v FOLLISTATIN-LIKE 3
(Homo
sapiens) 		4 / 4 HIS C  50
PRO C  51
LYS C  54
ILE C  55
 None
 1.38A 1lquA-3b4vC:
0.0		 1lquA-3b4vC:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3b4v FOLLISTATIN-LIKE 3
(Homo
sapiens) 		5 / 9 SER C 134
GLY C 110
GLU C 119
SER C 111
ASP C 112
 None
 1.50A 1pk9B-3b4vC:
undetectable		 1pk9B-3b4vC:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 3b4v FOLLISTATIN-LIKE 3
(Homo
sapiens) 		4 / 7 MET C 136
ASP C 112
TYR C 137
HIS C 165
 None
 1.46A 2bytA-3b4vC:
undetectable		 2bytA-3b4vC:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 3b4v FOLLISTATIN-LIKE 3
(Homo
sapiens) 		4 / 7 MET C 136
ASP C 112
TYR C 137
HIS C 165
 None
 1.46A 2bytD-3b4vC:
undetectable		 2bytD-3b4vC:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3b4v FOLLISTATIN-LIKE 3
(Homo
sapiens) 		4 / 8 MET C 136
ASP C 112
TYR C 137
HIS C 165
 None
 1.36A 2v0gA-3b4vC:
undetectable		 2v0gA-3b4vC:
13.37