SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		3 / 3 ASP A 123
ARG A 124
ILE A 168
 MG  A 210 (-3.2A)
None
None
 0.88A 1a4gB-3b57A:
undetectable		 1a4gB-3b57A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A  30
PHE A  18
THR A  73
LEU A  76
 None
 0.91A 1v55N-3b57A:
undetectable
1v55W-3b57A:
undetectable		 1v55N-3b57A:
16.01
1v55W-3b57A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A  30
PHE A  18
THR A  73
LEU A  76
 None
 0.89A 2einA-3b57A:
undetectable
2einJ-3b57A:
undetectable		 2einA-3b57A:
16.01
2einJ-3b57A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 8 GLY A  46
ILE A 180
VAL A  33
THR A 174
 None
 0.86A 2yoeB-3b57A:
3.8
2yoeC-3b57A:
3.7		 2yoeB-3b57A:
19.29
2yoeC-3b57A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A  30
PHE A  18
THR A  73
LEU A  76
 None
 0.87A 3abmN-3b57A:
undetectable
3abmW-3b57A:
undetectable		 3abmN-3b57A:
16.01
3abmW-3b57A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A  30
PHE A  18
THR A  73
LEU A  76
 None
 0.92A 3asoN-3b57A:
undetectable
3asoW-3b57A:
undetectable		 3asoN-3b57A:
16.01
3asoW-3b57A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 8 TRP A  34
PHE A  57
GLU A  52
ILE A   6
 None
 1.01A 3e7gC-3b57A:
undetectable
3e7gD-3b57A:
undetectable		 3e7gC-3b57A:
19.44
3e7gD-3b57A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		3 / 3 PHE A 191
GLN A 185
PHE A 137
 None
 0.79A 3rv5A-3b57A:
undetectable		 3rv5A-3b57A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 137
PHE A 161
ILE A 133
GLY A 132
 None
 0.98A 4ejjC-3b57A:
undetectable		 4ejjC-3b57A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 6 GLY A  46
GLY A  45
GLU A 115
ILE A 118
 None
 0.93A 4fglD-3b57A:
undetectable		 4fglD-3b57A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 7 ILE A  30
PHE A  18
THR A  73
LEU A  76
 None
 0.90A 5b1bN-3b57A:
undetectable
5b1bW-3b57A:
undetectable		 5b1bN-3b57A:
16.01
5b1bW-3b57A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		4 / 8 ILE A 118
LYS A  38
VAL A 119
GLU A  52
 None
 1.00A 5dqyA-3b57A:
undetectable		 5dqyA-3b57A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3b57 LIN1889 PROTEIN
(Listeria
innocua) 		5 / 12 ILE A  85
THR A 113
GLU A 115
PHE A  57
ALA A  10
 None
 1.37A 5iwuA-3b57A:
undetectable		 5iwuA-3b57A:
23.08