SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b5e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 3b5e MLL8374 PROTEIN
(Mesorhizobium
japonicum) 		4 / 6 ASN A 122
HIS A 198
GLY A 116
TYR A 117
 EDO  A 229 (-3.2A)
None
None
EDO  A 232 (-4.6A)
 1.12A 1c8lA-3b5eA:
undetectable		 1c8lA-3b5eA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1200_1
(SERUM ALBUMIN)		 3b5e MLL8374 PROTEIN
(Mesorhizobium
japonicum) 		4 / 4 LEU A  48
ILE A 163
ILE A 207
ALA A 206
 None
 0.69A 2i30A-3b5eA:
undetectable		 2i30A-3b5eA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 3b5e MLL8374 PROTEIN
(Mesorhizobium
japonicum) 		4 / 7 LEU A  35
LEU A 155
VAL A 135
LEU A 140
 None
 0.95A 3g8iA-3b5eA:
undetectable		 3g8iA-3b5eA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3b5e MLL8374 PROTEIN
(Mesorhizobium
japonicum) 		4 / 7 ILE A 162
VAL A 179
LEU A 182
SER A 183
 None
 0.67A 3r9vA-3b5eA:
undetectable
3r9vB-3b5eA:
undetectable		 3r9vA-3b5eA:
21.41
3r9vB-3b5eA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3b5e MLL8374 PROTEIN
(Mesorhizobium
japonicum) 		4 / 5 PHE A 114
PHE A  94
ALA A  95
LEU A 109
 None
 1.23A 3t3zC-3b5eA:
undetectable		 3t3zC-3b5eA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_2
(PUTATIVE ADENOSINE
KINASE)		 3b5e MLL8374 PROTEIN
(Mesorhizobium
japonicum) 		4 / 5 LEU A  21
ALA A 101
THR A  57
PHE A  33
 None
 1.38A 3vasB-3b5eA:
4.6		 3vasB-3b5eA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3b5e MLL8374 PROTEIN
(Mesorhizobium
japonicum) 		5 / 10 LEU A 181
THR A 160
VAL A 189
ALA A 187
LEU A 129
 None
 1.01A 6czmA-3b5eA:
undetectable
6czmC-3b5eA:
undetectable		 6czmA-3b5eA:
22.49
6czmC-3b5eA:
22.49