SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b5m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JFF_B_TA1B601_1 (TUBULIN BETA CHAIN)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.22A	1jffB-3b5mA: undetectable	1jffB-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HXF_B_TA1B601_1 (TUBULIN BETA CHAIN)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.22A	2hxfB-3b5mA: undetectable	2hxfB-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HXH_B_TA1B601_1 (TUBULIN BETA CHAIN)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.22A	2hxhB-3b5mA: undetectable	2hxhB-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P4N_B_TA1B601_1 (TUBULIN BETA CHAIN)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.22A	2p4nB-3b5mA: undetectable	2p4nB-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W3V_A_TOPA1169_1 (DIHYDROFOLATE REDUCTASE)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 104 LEU A 26 PHE A 37 ILE A 59 THR A 107	None	1.11A	2w3vA-3b5mA: undetectable	2w3vA-3b5mA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WBE_B_TA1B1439_1 (TUBULIN BETA-2B CHAIN)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.22A	2wbeB-3b5mA: undetectable	2wbeB-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DCO_B_TA1B601_1 (BOVINE BETA TUBULIN)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.22A	3dcoB-3b5mA: undetectable	3dcoB-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EDL_B_TA1B601_1 (BETA TUBULIN)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.22A	3edlB-3b5mA: undetectable	3edlB-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_A_CHDA3_0 (FERROCHELATASE, MITOCHONDRIAL)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	4 / 4	LEU A 39 PRO A 41 LEU A 118 ARG A 105	None	1.22A	3hcoA-3b5mA: undetectable	3hcoA-3b5mA: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCO_B_CHDB1_0 (FERROCHELATASE, MITOCHONDRIAL)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	4 / 4	LEU A 39 PRO A 41 LEU A 118 ARG A 105	None	1.01A	3hcoB-3b5mA: undetectable	3hcoB-3b5mA: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IZ0_B_TA1B820_1 (BETA TUBULIN, CHAIN B FROM PDB 1JFF)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	VAL A 7 LEU A 26 LEU A 38 ARG A 121 GLY A 55	None	1.21A	3iz0B-3b5mA: undetectable	3iz0B-3b5mA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F4D_A_CHDA506_0 (FERROCHELATASE, MITOCHONDRIAL)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	4 / 4	PRO A 27 LEU A 26 ILE A 24 ARG A 40	None	1.22A	4f4dA-3b5mA: undetectable	4f4dA-3b5mA: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_A_RITA602_1 (CYTOCHROME P450 3A5)	3b5m	UNCHARACTERIZED PROTEIN (Rhodopirellula baltica)	5 / 12	ARG A 187 ILE A 159 ALA A 147 ALA A 69 GLY A 74	None	0.83A	5veuA-3b5mA: undetectable	5veuA-3b5mA: 17.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1JFF_B_TA1B601_1","TUBULIN BETA CHAIN","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.22A","1jffB-3b5mA:undetectable","1jffB-3b5mA:18.61"],["2HXF_B_TA1B601_1","TUBULIN BETA CHAIN","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.22A","2hxfB-3b5mA:undetectable","2hxfB-3b5mA:18.61"],["2HXH_B_TA1B601_1","TUBULIN BETA CHAIN","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.22A","2hxhB-3b5mA:undetectable","2hxhB-3b5mA:18.61"],["2P4N_B_TA1B601_1","TUBULIN BETA CHAIN","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.22A","2p4nB-3b5mA:undetectable","2p4nB-3b5mA:18.61"],["2W3V_A_TOPA1169_1","DIHYDROFOLATE REDUCTASE","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A 104;LEU A  26;PHE A  37;ILE A  59;THR A 107","None","1.11A","2w3vA-3b5mA:undetectable","2w3vA-3b5mA:25.00"],["2WBE_B_TA1B1439_1","TUBULIN BETA-2B CHAIN","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.22A","2wbeB-3b5mA:undetectable","2wbeB-3b5mA:18.61"],["3DCO_B_TA1B601_1","BOVINE BETA TUBULIN","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.22A","3dcoB-3b5mA:undetectable","3dcoB-3b5mA:18.61"],["3EDL_B_TA1B601_1","BETA TUBULIN","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.22A","3edlB-3b5mA:undetectable","3edlB-3b5mA:18.61"],["3HCO_A_CHDA3_0","FERROCHELATASE, MITOCHONDRIAL","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",4,"LEU A  39;PRO A  41;LEU A 118;ARG A 105","None","1.22A","3hcoA-3b5mA:undetectable","3hcoA-3b5mA:21.92"],["3HCO_B_CHDB1_0","FERROCHELATASE, MITOCHONDRIAL","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",4,"LEU A  39;PRO A  41;LEU A 118;ARG A 105","None","1.01A","3hcoB-3b5mA:undetectable","3hcoB-3b5mA:21.92"],["3IZ0_B_TA1B820_1","BETA TUBULIN, CHAIN B FROM PDB 1JFF","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"VAL A   7;LEU A  26;LEU A  38;ARG A 121;GLY A  55","None","1.21A","3iz0B-3b5mA:undetectable","3iz0B-3b5mA:18.61"],["4F4D_A_CHDA506_0","FERROCHELATASE, MITOCHONDRIAL","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",4,"PRO A  27;LEU A  26;ILE A  24;ARG A  40","None","1.22A","4f4dA-3b5mA:undetectable","4f4dA-3b5mA:21.92"],["5VEU_A_RITA602_1","CYTOCHROME P450 3A5","3b5m","UNCHARACTERIZED PROTEIN","Rhodopirellula baltica",5,"ARG A 187;ILE A 159;ALA A 147;ALA A  69;GLY A  74","None","0.83A","5veuA-3b5mA:undetectable","5veuA-3b5mA:17.11"]]