SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b5o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		4 / 7 HIS A 178
HIS A  94
THR A  89
THR A  88
 None
 1.07A 1am6A-3b5oA:
undetectable		 1am6A-3b5oA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 LEU A 106
LEU A 102
GLY A 101
VAL A 156
ALA A 166
 None
 1.13A 2oz7A-3b5oA:
undetectable		 2oz7A-3b5oA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		4 / 7 GLY A 139
ILE A 144
THR A  58
LEU A 138
 None
 0.89A 2xrhA-3b5oA:
undetectable		 2xrhA-3b5oA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 12 ALA A  61
GLY A  56
LEU A 123
ARG A 124
VAL A 126
 None
 1.08A 3o7wA-3b5oA:
undetectable		 3o7wA-3b5oA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ACTA908_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		4 / 4 MET A  44
SER A  48
LEU A 102
VAL A 110
 None
 1.31A 3vlnA-3b5oA:
0.1		 3vlnA-3b5oA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		5 / 11 LEU A 179
LYS A 157
VAL A 156
TYR A  47
PHE A 174
 None
 1.16A 5gpgA-3b5oA:
undetectable		 5gpgA-3b5oA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		4 / 8 LEU A 171
LEU A 152
TYR A  95
GLN A  46
 None
 1.07A 5hbsA-3b5oA:
undetectable		 5hbsA-3b5oA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3b5o CADD-LIKE PROTEIN OF
UNKNOWN FUNCTION
(Nostoc
punctiforme) 		4 / 8 LEU A 171
LEU A 152
ILE A  49
GLN A  46
 None
 1.05A 5ljbA-3b5oA:
undetectable		 5ljbA-3b5oA:
20.00