SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b6e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3b6e INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU A 481
PRO A 482
ARG A 459
 None
 0.55A 4klrB-3b6eA:
2.6		 4klrB-3b6eA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 3b6e INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 10 ILE A 441
ILE A 442
ILE A 326
ILE A 327
ILE A 325
 None
 1.04A 5murE-3b6eA:
undetectable		 5murE-3b6eA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_B_PFLB510_1
(PROTON-GATED ION
CHANNEL)		 3b6e INTERFERON-INDUCED
HELICASE C
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 6 ILE A 457
ALA A 414
LEU A 417
ILE A 360
 None
 0.86A 5mvmB-3b6eA:
undetectable
5mvmC-3b6eA:
undetectable		 5mvmB-3b6eA:
22.94
5mvmC-3b6eA:
22.94