SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3b6n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
vivax) 		5 / 12 VAL A  52
ILE A 140
ILE A  68
VAL A  54
LEU A  47
 None
 0.99A 1qhsA-3b6nA:
undetectable		 1qhsA-3b6nA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
vivax) 		4 / 7 ILE A  68
ILE A 133
SER A 145
VAL A 155
 None
 0.81A 3ua5B-3b6nA:
undetectable		 3ua5B-3b6nA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
vivax) 		3 / 3 LYS A   4
TYR A 117
ARG A 184
 None
 1.19A 4gc9A-3b6nA:
undetectable		 4gc9A-3b6nA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
vivax) 		5 / 10 ILE A 140
ASP A  66
LEU A  76
ILE A 144
THR A  48
 None
 1.31A 4km0A-3b6nA:
undetectable		 4km0A-3b6nA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
vivax) 		4 / 8 ALA A  71
LEU A 105
ILE A 119
VAL A 155
 None
 0.84A 5nujA-3b6nA:
undetectable		 5nujA-3b6nA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE
(Plasmodium
vivax) 		4 / 8 ALA A  75
LEU A 105
ILE A 150
VAL A 155
 None
 0.51A 5nujA-3b6nA:
undetectable		 5nujA-3b6nA:
21.25